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The map label for this gene is ygcN [H]

Identifier: 157162216

GI number: 157162216

Start: 2909889

End: 2911160

Strand: Direct

Name: ygcN [H]

Synonym: EcHS_A2906

Alternate gene names: 157162216

Gene position: 2909889-2911160 (Clockwise)

Preceding gene: 157162215

Following gene: 157162217

Centisome position: 62.67

GC content: 55.58

Gene sequence:

>1272_bases
ATGGAAGACGACTGCGACATTATTATTATTGGTGCCGGTATTGCAGGCACCGCTTGCGCGTTACGCTGCGCGCGAGCGGG
TTTATCCGTTTTGTTACTGGAACGCGCTGAAATCCCCGGCAGCAAAAATCTTTCCGGCGGGCGGTTATATACCCATGCAC
TCGCGGAACTCCTCCCTCAGTTTCATCTGACTGCGCCTCTTGAACGACGCATCACTCACGAAAGCCTTTCCCTGTTAACG
CCCGATGGCGCAACGACGTTTTCCAGCTTACAGCCCGGCGGTGAATCCTGGAGTGTATTACGTGCACGGTTCGATCCGTG
GCTGGTTGCCGAAGCCGAAAAAGAAGGTGTCGAATGCATCCCCGGAGCGACGGTGGATGCACTGTATGAAGAAAACGGCA
GGGTGTGTGGTGTCATTTGTGGTGACGATATTCTCCGTGCCCGTTATGTGGTGCTGGCAGAAGGTGCCAACAGCGTCCTG
GCTGAGCGTCACGGGTTAGTGACTCGTCCTGCTGGCGAAGCGATGGCGTTGGGGATCAAAGAAGTGCTGTCGCTGGAACC
ATCCGCTATTGAAGAACGTTTTCATCTGGAGAATAACGAAGGCGCAGCGTTGCTGTTCAGCGGCAGGATCTGTGATGACT
TACCCGGCGGCGCATTTCTTTATACTAATCAACAAACGCTCTCGTTAGGGATTGTTTGCCCGCTCTCTTCCCTTACGCAA
AGTCGTGTTCCGGCAAGCGAGCTGCTGACTCGCTTTAAAGCGCATCCGGCAGTGCGCCCGCTTATCAAAAACACGGAATC
ACTGGAGTATGGTGCGCATCTGGTGCCAGAAGGTGGCTTGCACAGTATGCCGGTGCAATACGCCGGTAACGGCTGGCTGC
TGGTGGGCGATGCGTTGCGCAGTTGCGTCAATACCGGAATTTCCGTGCGCGGCATGGATATGGCGCTGACTGGCGCGCAG
GCGGCGGCACAAACGCTGATAAGCGCCTGCCAGCACCGCGAGCCGCAAAATCTGTTTGCGCTTTATCATCACAACGTCGA
GCGCAGCCTGCTGTGGGATATTCTACAGCGTTATCAGCATGTTCCGGCGCTTTTGCAACGCCCTGGCTGGTATCGGGCGT
GGCCTGCGTTAATGCAGGATATTTCCCGCGATTTATGGGATCAGGGTGATAAACCTGTTCCACCGCTGCGCCAGTTATTC
TGGCGTCATTTACGTCGTCATGGCCTGTGGCATCTGGCGGGCGATGTTATCAGGAGTGTTCGATGTCTGTAG

Upstream 100 bases:

>100_bases
GGTGTATCTATCGCGGCGAATGATAAGAGTGTGTCGGCGGTCAATTTCCCTTAAGTAACGCTATGTTAGGGTGTTGTGTT
CTGGATATCTGGGGCATGAC

Downstream 100 bases:

>100_bases
CCCATAATCTCTGGCGCGTTGCTGATGCGCCGCACATTGTTCCGGCTGACTCCGTTGAGCGTCAGATGGTACAACGGTTG
ATTAACGCCTGTCCGGCAGG

Product: pyridine nucleotide-disulfide oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLF
WRHLRRHGLWHLAGDVIRSVRCL

Sequences:

>Translated_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLF
WRHLRRHGLWHLAGDVIRSVRCL
>Mature_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLF
WRHLRRHGLWHLAGDVIRSVRCL

Specific function: Probably accepts electrons from ygcQ/ygcR and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=400, Percent_Identity=24.75, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87082155, Length=423, Percent_Identity=98.3451536643026, Blast_Score=847, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=428, Percent_Identity=42.7570093457944, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=41.3551401869159, Blast_Score=333, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI25144720, Length=366, Percent_Identity=27.0491803278689, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324932, Length=367, Percent_Identity=26.9754768392371, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24652256, Length=409, Percent_Identity=26.161369193154, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 46325; Mature: 46325

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHEECCCCCCHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RCL
CCC
>Mature Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHEECCCCCCHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDILQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSV
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RCL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]