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The map label for this gene is cas1 [H]

Identifier: 157162204

GI number: 157162204

Start: 2896088

End: 2897005

Strand: Reverse

Name: cas1 [H]

Synonym: EcHS_A2894

Alternate gene names: 157162204

Gene position: 2897005-2896088 (Counterclockwise)

Preceding gene: 157162205

Following gene: 157162202

Centisome position: 62.39

GC content: 50.65

Gene sequence:

>918_bases
ATGGCTTGGCTTCCTCTTAACCCCATTCCACTCAAAGATCGCGTCTCCATGATCTTTCTGCAATATGGGCAGATCGATGT
AATAGATGGCGCGTTTGTACTTATCGACAAGACAGGGATCCGCACTCATATTCCTGTTGGCTCGGTTGCCTGCATCATGC
TGGAACCTGGTACACGGGTTTCGCATGCAGCTGTACGCTTGGCTGCGCAAGTTGGAACATTGTTGGTATGGGTGGGGGAA
GCGGGCGTTCGTGTTTATGCTTCTGGTCAGCCTGGTGGTGCGCGTTCAGATAAGCTGCTCTACCAGGCAAAACTTGCTCT
GGATGAAGATTTGCGTCTGAAGGTAGTACGCAAAATGTTTGAACTTCGGTTTGGTGAACCTGCGCCCGCCCGACGCTCCG
TAGAACAACTCAGAGGTATAGAAGGAAGCCGTGTGCGAGCAACTTATGCACTTCTGGCGAAGCAATACGGGGTGACATGG
AATGGACGTCGTTACGATCCGAAAGACTGGGAAAAGGGCGATACGGTCAACCAATGCATTAGCGCTGCAACTTCCTGTTT
ATACGGCGTAACTGAAGCGGCGATACTTGCAGCTGGTTATGCACCAGCTATTGGGTTTGTGCATACAGGAAAGCCTCTTT
CCTTTGTTTACGATATCGCGGACATCATTAAATTTGACACTGTTGTACCGAAAGCTTTTGAGATAGCGCGTTGTAATCCT
GGTGAGCCGGACCGGGAAGTCCGTTTGGCGTGCAGGGATATTTTTCGCAGTAGTAAAACATTAGCCAAATTGATTCCGCT
TATAGAGGACGTGCTTGCTGCTGGAGAAATACAACCGCCGGCCCCACCTGAAGATGCACAGCCTGTTGCCATTCCGCTTC
CTGTTTCACTGGGAGATGCAGGCCATCGGAGTAGCTGA

Upstream 100 bases:

>100_bases
GCCAGCGTTAATAGATCTTTTACAGCAAGGTATTGGGCCAGCCAAATCGATGGGATGTGGTTTGCTATCTTTGGCTCCAC
TGTGATTGAGGTGTAATAAA

Downstream 100 bases:

>100_bases
AATGAGTATGTTGGTCGTGGTCACTGAAAATGTACCTCCGCGCTTACGAGGCAGATTAGCCATCTGGTTGTTGGAGGTAC
GTGCAGGGGTATATGTAGGT

Product: CRISPR-associated Cas1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE
AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW
NGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARCNP
GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS

Sequences:

>Translated_305_residues
MAWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE
AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW
NGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARCNP
GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>Mature_304_residues
AWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA
GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN
GRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARCNPG
EPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS

Specific function: Unknown

COG id: COG1518

COG function: function code L; Uncharacterized protein predicted to be involved in DNA repair

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789113, Length=305, Percent_Identity=99.016393442623, Blast_Score=612, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002729
- InterPro:   IPR019851 [H]

Pfam domain/function: PF01867 DUF48 [H]

EC number: NA

Molecular weight: Translated: 33098; Mature: 32967

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV
CCCCCCCCCCCHHHHEEEEEECCCEEEECCEEEEEECCCCEEECCCCCEEEEEECCCCCH
SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF
HHHHHHHHHHHCEEEEEECCCCEEEEECCCCCCCCCCHHHEEHHHHCCCHHHHHHHHHHH
ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTVNQCI
HHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARCNP
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHEECCCC
GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEECCCC
GHRSS
CCCCC
>Mature Secondary Structure 
AWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV
CCCCCCCCCCHHHHEEEEEECCCEEEECCEEEEEECCCCEEECCCCCEEEEEECCCCCH
SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF
HHHHHHHHHHHCEEEEEECCCCEEEEECCCCCCCCCCHHHEEHHHHCCCHHHHHHHHHHH
ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTVNQCI
HHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARCNP
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHEECCCC
GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEECCCC
GHRSS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]