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The map label for this gene is ypdC

Identifier: 157161855

GI number: 157161855

Start: 2532532

End: 2533389

Strand: Direct

Name: ypdC

Synonym: EcHS_A2519

Alternate gene names: 157161855

Gene position: 2532532-2533389 (Clockwise)

Preceding gene: 157161854

Following gene: 157161862

Centisome position: 54.54

GC content: 53.73

Gene sequence:

>858_bases
ATGAAAGCACCAGGCTTGCCCGCCGATCAACAATTTTTCGCCGATCTGTTCAGCGGCCTGGTGCTTAACCCGCAACTACT
GGGGCGCGTCTGGTTTGCCAGCCAGCCTGCCTCGTTGCCGGTGGGCAGTTTATGTATTGATTTTCCCCGTCTGGATATCG
TGCTGCGCGGCGAATACGGCAATCTGCTGGAAGCAAAGCAGCAACGTTTGGTGGAAGGAGAAATGCTGTTTATTCCGGCG
CGCGCGGCTAATTTACCGGTCAACAACAAACCGGTGATGCTGTTAAGCCTGGTGTTCGCGCCGACCTGGCTTGGGTTATC
GTTTTACGATAGCCGCACCACGTCGTTGTTGCATCCTGCTCGCCAGATCCAGCTTCCCAGCCTGCAACGCGGTGAAGGTG
AAGCGATGCTTACCGCCCTCACCCATCTTAGCCGTTCGCCGCTGGAGCAAAATATCATTCAGCCGCTGGTGTTAAGTTTG
CTGCATCTTTGCCGTAGCGTGGTGAATATGCCGCCGGGCAATTCGCAGCCGCGCGGCGATTTTCTCTATCACAGCATTTG
TAACTGGGTTCAGGATAATTATGCCCAGCCGCTCACCCGCGAGAGCGTGGCGCAGTTTTTTAATATCACGCCCAATCATC
TGTCAAAACTGTTTGCTCAGCATGGAACGATGCGTTTTATCGAGTATGTGCGTTGGGTGCGAATGGCGAAGGCGAGGATG
ATTTTGCAGAAATATCATCTGTCAATTCATGAAGTGGCACAGCGTTGCGGTTTTCCGGATAGCGACTATTTTTGTCGCGT
TTTCCGGCGTCAGTTTGGTCTGACGCCGGGAGAGTACAGCGCCCGTTTTCAGGGCTAA

Upstream 100 bases:

>100_bases
CTACATTCTGCGACTGAAAGATCTGGATTTTGAAGTGCCGGTCAGCCGCAGCAAAGTGAAAGAATTTCGCCAGTTAATGC
ATCTTTAATCGGGAACTTTC

Downstream 100 bases:

>100_bases
CGTCAGAAGGTTAATTCTGTTTCCAGCAGCGTCAGGATACTTTGTGCATCTTGCGCGGCAAACAACGACTGGCGGAAGTT
TTTATTCACCAGTTTACGCG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPA
RAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
LHLCRSVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG

Sequences:

>Translated_285_residues
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPA
RAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
LHLCRSVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG
>Mature_285_residues
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPA
RAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
LHLCRSVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788725, Length=285, Percent_Identity=100, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1790391, Length=271, Percent_Identity=35.4243542435424, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI171474011, Length=242, Percent_Identity=24.3801652892562, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790339, Length=88, Percent_Identity=31.8181818181818, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YPDC_ECOLI (P77396)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C65012
- RefSeq:   AP_002982.1
- RefSeq:   NP_416883.1
- ProteinModelPortal:   P77396
- IntAct:   P77396
- STRING:   P77396
- EnsemblBacteria:   EBESCT00000001391
- EnsemblBacteria:   EBESCT00000016141
- GeneID:   946856
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2379
- KEGG:   eco:b2382
- EchoBASE:   EB3902
- EcoGene:   EG14150
- eggNOG:   COG2207
- GeneTree:   EBGT00050000008635
- HOGENOM:   HBG416924
- OMA:   RMAKARI
- ProtClustDB:   CLSK880376
- BioCyc:   EcoCyc:G7245-MONOMER
- Genevestigator:   P77396
- GO:   GO:0005622
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF00165 HTH_AraC; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 32356; Mature: 32356

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCC
NLLEAKQQRLVEGEMLFIPARAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPA
CHHHHHHHHHHCCCEEEEECHHCCCCCCCCCHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
RQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSLLHLCRSVVNMPPGNSQPRGD
HHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCC
NLLEAKQQRLVEGEMLFIPARAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPA
CHHHHHHHHHHCCCEEEEECHHCCCCCCCCCHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
RQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSLLHLCRSVVNMPPGNSQPRGD
HHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
FLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503