BacMap

Definition	Escherichia coli HS, complete genome.
Accession	NC_009800
Length	4,643,538

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The map label for this gene is yohF [H]

Identifier: 157161619

GI number: 157161619

Start: 2268907

End: 2269668

Strand: Reverse

Name: yohF [H]

Synonym: EcHS_A2272

Alternate gene names: 157161619

Gene position: 2269668-2268907 (Counterclockwise)

Preceding gene: 157161620

Following gene: 157161617

Centisome position: 48.88

GC content: 55.38

Gene sequence:

>762_bases
ATGGCACAGGTTGCGATTATTACCGCCTCCGATTCGGGGATCGGCAAAGAGTGCGCGTTATTACTGGCGCAGCAGGGGTT
TGATATTGGTATTACCTGGAACTCAGATGAAGAAGGGGCAAAAGATACCGCGCGTGAGGTAGTTAGCCACGGCGTACGTG
CGGAGATCGTGCAGCTGGATCTCGGTAAACTGCCAGAAGGTGCGCAGGCGCTGGAGAAACTCATTCAACGGCTGGGGCGT
ATTGATGTGCTGGTGAATAATGCGGGCGCAATGACCAAAGCGCCGTTTCTTGATATGGCTTTCGATGAGTGGCGCAAGAT
TTTTACCGTTGATGTCGATGGTGCATTTTTATGCTCACAAATTGCGGCCCGCCAGATGGTGAAACAAGGGCAGGGCGGTC
GCATCATCAACATTACGTCGGTACATGAACATACGCCGCTGCCGGATGCCAGCGCCTACACAGCCGCTAAACATGCGCTC
GGTGGGTTAACCAAAGCGATGGCGCTGGAGCTGGTCAGGCATAAGATTTTGGTGAACGCAGTCGCGCCTGGGGCGATCGC
CACGCCAATGAATGGCATGGATGACAGCGACGTGAAGCCCGACGCGGAGCCTTCGATTCCTCTGCGGCGTTTTGGCGCAA
CGCATGAGATTGCCAGCCTGGTAGCGTGGCTGTGCTCAGAGGGCGCAAATTACACCACCGGGCAGTCGTTGATAGTGGAT
GGCGGCTTTATGTTGGCGAATCCGCAGTTCAACCCAGAATAG

Upstream 100 bases:

>100_bases
GCCTCCATTCAACTCACTGGTGCGTTGGGCGGGGGTTACAAACGCTGATGATATGCGCCTTCTATACTTAACGTTTATTC
AGCGTTAAGTGGAGAACTCG

Downstream 100 bases:

>100_bases
CGCAGTGAGGTGCGTGGTTATTTCAATGGGTAAAATTTTGGTAGGCATGATAAGACGCACAAGCGTCGCATCAGGCATGG
TGCACCGGATGTCGGATGCG

Product: acetoin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MAQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGR
IDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
GGFMLANPQFNPE

Sequences:

>Translated_253_residues
MAQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGR
IDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
GGFMLANPQFNPE
>Mature_252_residues
AQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRI
DVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALG
GLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVDG
GFMLANPQFNPE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.8943089430894, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=32, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI7705925, Length=193, Percent_Identity=35.7512953367876, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=29.8387096774194, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=27.9527559055118, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=27.319587628866, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=27.3684210526316, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=27.9166666666667, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4503301, Length=246, Percent_Identity=24.390243902439, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=28, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI59889578, Length=221, Percent_Identity=28.0542986425339, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=26.4248704663212, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=169, Percent_Identity=26.6272189349112, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.8510638297872, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI225579078, Length=204, Percent_Identity=30.8823529411765, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=27.3224043715847, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=98.4189723320158, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=34.2857142857143, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=34.0080971659919, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.9180327868852, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=32.0987654320988, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=32.9218106995885, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=31.7460317460317, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=33.6065573770492, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=27.710843373494, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786812, Length=197, Percent_Identity=31.9796954314721, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.7992277992278, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=31.0077519379845, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.3501945525292, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=33.4600760456274, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=33.75, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=33.7448559670782, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=30.46875, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.4354838709677, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.8300395256917, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.3893129770992, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=29.0983606557377, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.5019157088123, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=31.2977099236641, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=27.8625954198473, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=31.1111111111111, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.4809160305344, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=26.7175572519084, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=29.5019157088123, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=27.9850746268657, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=30.9859154929577, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=27.3684210526316, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=27.3684210526316, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=27.1276595744681, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=29.296875, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.4, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=25.3588516746411, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=25, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=221, Percent_Identity=28.5067873303167, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=24.6268656716418, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=23.7903225806452, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=25, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=29.1845493562232, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=25.2032520325203, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=33.6032388663968, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=32.4, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=29.2682926829268, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=32.1888412017167, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=28.3400809716599, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=32.1243523316062, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644337, Length=223, Percent_Identity=30.0448430493274, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641232, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=25.9842519685039, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=26.2376237623762, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584752, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640492, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007238, Length=226, Percent_Identity=25.2212389380531, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=27.8947368421053, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26929; Mature: 26798

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGAKDTAREVVSHGVRAEIVQLD
CCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEE
LGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQ
CCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHH
IAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNA
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
CCCCCEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GGFMLANPQFNPE
CCEEEECCCCCCC
>Mature Secondary Structure 
AQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGAKDTAREVVSHGVRAEIVQLD
CEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEE
LGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQ
CCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHH
IAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNA
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
CCCCCEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GGFMLANPQFNPE
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]