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The map label for this gene is araH

Identifier: 157161371

GI number: 157161371

Start: 2002181

End: 2003167

Strand: Reverse

Name: araH

Synonym: EcHS_A1995

Alternate gene names: 157161371

Gene position: 2003167-2002181 (Counterclockwise)

Preceding gene: 157161372

Following gene: 157161370

Centisome position: 43.14

GC content: 51.17

Gene sequence:

>987_bases
ATGTCTTCTGTTTCTACATCGGGGTCTGGCGCACCTAAGTCGTCATTCAGCTTCGGGCGTATCTGGGATCAGTACGGCAT
GCTGGTGGTGTTTGCGGTGCTCTTTATCGCCTGTGCCATTTTTGTCCCAAATTTTGCCACCTTCATTAATATGAAAGGGT
TGGGCCTGGCAATTTCCATGTCGGGGATGGTGGCTTGTGGCATGTTGTTCTGCCTCGCTTCCGGTGACTTTGACCTTTCT
GTCGCCTCCGTAATTGCCTGTGCGGGTGTCACCACGGCGGTGGTTATTAACCTGACTGAAAGCCTGTGGATTGGCGTGGC
AGCGGGGTTGTTGCTGGGCGTTCTCTGTGGCCTGGTCAATGGCTTTGTTATCGCCAAACTGAAAATAAATGCTCTGATCA
CGACATTGGCAACGATGCAGATTGTTCGAGGTCTGGCGTACATCATTTCAGACGGTAAAGCGGTCGGTATCGAAGATGAA
AGCTTCTTTGCCCTTGGTTACGCCAACTGGTTCGGTCTGCCTGCGCCAATCTGGCTCACCGTCGCGTGTCTGATTATCTT
TGGTTTGCTGCTGAATAAAACCACCTTTGGTCGTAACACCCTGGCGATTGGCGGGAACGAAGAGGCCGCGCGTCTGGCGG
GTGTACCGGTTGTTCGCACCAAAATTATTATCTTTGTTCTCTCAGGCCTGGTATCAGCGATAGCCGGAATTATTCTGGCT
TCACGTATGACCAGTGGGCAGCCAATGACGTCGATTGGTTATGAGCTGATTGTTATCTCCGCCTGCGTTTTAGGTGGCGT
TTCTCTGAAAGGTGGCATCGGAAAAATCTCATATGTGGTGGCGGGTATCTTAATTTTAGGCACCGTGGAAAACGCCATGA
ACCTGCTTAATATTTCTCCTTTCGCGCAGTACGTGGTTCGCGGCTTAATCCTGCTGGCAGCGGTGATCTTCGACCGTTAC
AAGCAAAAAGCGAAACGCACTGTCTGA

Upstream 100 bases:

>100_bases
TCGCCGGTGAATTGTTACACGAGCAGGCAGATGAGCGTCAGGCACTGAGCCTTGCGATGCCTAAAGTCAGCCAGGCTGTT
GCCTGAGTAAGGAGAGTATG

Downstream 100 bases:

>100_bases
TGCTTTTTTCTGCAACAATTTAGCGTTTTTTCCCACCATAGCCAACCGCCATAACGGTTGGCTGTTCTTCGTTGCAAATG
GCGACCCCCGTCACACTGTC

Product: L-arabinose transporter permease protein

Products: ADP; phosphate; arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLS
VASVIACAGVTTAVVINLTESLWIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIILA
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRY
KQKAKRTV

Sequences:

>Translated_328_residues
MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLS
VASVIACAGVTTAVVINLTESLWIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIILA
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRY
KQKAKRTV
>Mature_327_residues
SSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSV
ASVIACAGVTTAVVINLTESLWIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDES
FFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIILAS
RMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYK
QKAKRTV

Specific function: Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI145693152, Length=328, Percent_Identity=100, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=310, Percent_Identity=35.8064516129032, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1790524, Length=318, Percent_Identity=30.188679245283, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1788896, Length=311, Percent_Identity=31.8327974276527, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789992, Length=132, Percent_Identity=46.2121212121212, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082395, Length=272, Percent_Identity=31.9852941176471, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787793, Length=256, Percent_Identity=35.15625, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788471, Length=321, Percent_Identity=30.8411214953271, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693214, Length=242, Percent_Identity=38.0165289256198, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787794, Length=274, Percent_Identity=28.8321167883212, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARAH_ECOLI (P0AE26)

Other databases:

- EMBL:   X06091
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X69160
- PIR:   S01075
- RefSeq:   AP_002517.1
- RefSeq:   YP_026162.2
- ProteinModelPortal:   P0AE26
- STRING:   P0AE26
- EnsemblBacteria:   EBESCT00000001367
- EnsemblBacteria:   EBESCT00000015248
- GeneID:   948923
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1887
- KEGG:   eco:b4460
- EchoBASE:   EB0057
- EcoGene:   EG10059
- eggNOG:   COG1172
- GeneTree:   EBGT00050000010180
- HOGENOM:   HBG663180
- OMA:   LTIISAC
- ProtClustDB:   PRK11285
- BioCyc:   EcoCyc:ARAH-MONOMER
- Genevestigator:   P0AE26
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 34211; Mature: 34080

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfcce6f0)-; HASH(0x156fb05c)-; HASH(0x152de100)-; HASH(0x14fbc75c)-; HASH(0x13a6f6c4)-; HASH(0x1521d908)-; HASH(0x153c3f34)-; HASH(0x1508340c)-; HASH(0x15607258)-; HASH(0x1560cfdc)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEH
SGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESLWIGVAAGLLLGVLCGLVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDESFFALGYANWFGLPAPIWLT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEHHHCCCCHHHHHH
VACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIILA
HHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISP
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FAQYVVRGLILLAAVIFDRYKQKAKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEH
SGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESLWIGVAAGLLLGVLCGLVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDESFFALGYANWFGLPAPIWLT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEHHHCCCCHHHHHH
VACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIILA
HHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISP
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FAQYVVRGLILLAAVIFDRYKQKAKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arabinose [Periplasm]; H2O [C]

Specific reaction: ATP + arabinose [Periplasm] + H2O = ADP + phosphate + arabinose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2445996; 9097040; 9278503; 8045430