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The map label for this gene is uspC [H]

Identifier: 157161368

GI number: 157161368

Start: 1999380

End: 1999808

Strand: Direct

Name: uspC [H]

Synonym: EcHS_A1992

Alternate gene names: 157161368

Gene position: 1999380-1999808 (Clockwise)

Preceding gene: 157161367

Following gene: 157161374

Centisome position: 43.06

GC content: 45.22

Gene sequence:

>429_bases
ATGAGCTATAGCAATATTCTTGTCGCTGTTGCGGTTACACCGGAAAGTCAGCAACTGCTGGCAAAAGCGGTATCTATCGC
CAGGCCAGTAAAGGGACACATCAGTTTAATTACTCTCGCTTCCGACCCGGAAATGTACAATCAATTAGCTGCGCCGATGC
TTGAAGATTTACGCAGCGTGATGCAGGAAGAAACGCAAAGCTTTCTTGATAAGTTAATTCAGGATGCGGGGTATCCCGTT
GACAAGACGTTTATTGCCTACGGTGAGTTAAGCGAACATATTCTGGAAGTATGTCACAAGCATCATTTCGATTTGGTGAT
TTGCGGTAATCACAATCACAGTTTCTTTTCGCGAGCATCCTGCTCGGCGAAAAGAGTTATTGCCTCAAGTGAGGTCGATG
TGCTGTTAGTTCCACTTACGGGAGATTAA

Upstream 100 bases:

>100_bases
GACTAATATTTACCAGTTTGACCGAGTTGGGATTGCGTCGTTTCTCCATTAGGAGTAAAGCTTTAATGTCACCTGAAGTT
CACAGAATAAGGAACAGGTT

Downstream 100 bases:

>100_bases
CCGCTCCTACGCAAGCTTTGGAAAGGTAGCAACTTTATCGCGCTGCTGGCTTTCCGCGCTTCGCGGAACTATCTGCTTTA
GGTCGCTAATGAAGCACTCC

Product: universal stress protein UspC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPV
DKTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD

Sequences:

>Translated_142_residues
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPV
DKTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD
>Mature_141_residues
SYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVD
KTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1788205, Length=142, Percent_Identity=99.2957746478873, Blast_Score=290, Evalue=3e-80,
Organism=Escherichia coli, GI1789909, Length=140, Percent_Identity=38.5714285714286, Blast_Score=101, Evalue=1e-23,
Organism=Escherichia coli, GI1790358, Length=140, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15624; Mature: 15493

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSV
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
MQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRAS
HHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCC
CSAKRVIASSEVDVLLVPLTGD
CCHHHHEECCCCCEEEEEECCC
>Mature Secondary Structure 
SYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSV
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
MQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRAS
HHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCC
CSAKRVIASSEVDVLLVPLTGD
CCHHHHEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]