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The map label for this gene is ydhB [H]

Identifier: 157161125

GI number: 157161125

Start: 1760890

End: 1761822

Strand: Reverse

Name: ydhB [H]

Synonym: EcHS_A1739

Alternate gene names: 157161125

Gene position: 1761822-1760890 (Counterclockwise)

Preceding gene: 157161128

Following gene: 157161123

Centisome position: 37.94

GC content: 53.8

Gene sequence:

>933_bases
ATGTGGTCAGAATATTCACTCGAAGTTGTTGATGCGGTAGCGCGTAATGGTAGTTTTAGCGCTGCGGCACAGGAGCTGCA
TCGCGTTCCTTCTGCGGTCAGCTATACCGTGCGTCAGCTGGAAGAGTGGCTGGCGGTGCCGCTCTTTGAACGACGGCACC
GTGATGTGGAGCTGACCGCTGCTGGAGCGTGGTTTCTCAAAGAAGGGCGCTCTGTTGTCAAAAAAATGCAGATCACCCGC
CAGCAATGTCAGCAGATAGCGAACGGCTGGCGCGGTCAGTTAGCTATCGCAGTGGATAATATTGTCAGGCCAGAACGTAC
ACGGCAGATGATCGTTGATTTTTATCGCCATTTTGATGATGTCGAACTTCTTGTCTTTCAGGAAGTGTTCAACGGTGTCT
GGGATGCGCTTTCCGACGGGCGCGTGGAACTGGCGATTGGCGCAACACGCGCGATTCCGGTAGGCGGTCGTTATGCCTTC
CGGGATATGGGGATGCTAAGCTGGAGTTGCGTTGTTGCCAGCCACCACCCGCTGGCGTTGATGGATGGCCCATTCAGCGA
TGATACGTTGCGCAACTGGCCGTCGTTGGTGCGCGAAGACACCTCGCGAACGCTACCTAAGCGTATTACCTGGTTGCTGG
ATAACCAAAAAAGACTTGTCGTGCCTGACTGGGAATCATCGGCAACCTGTATCTCGGCAGGATTATGCATAGGGATGGTG
CCAACACATTTCGCCAAACCGTGGCTTAATGAGGGGAAGTGGGTAGCATTAGAACTGGAAAACCCCTTTCCGGATTCGGC
ATGTTGTCTGACATGGCAGCAAAATGATATGTCGCCTGCGTTAACCTGGTTGCTTGAGTATCTCGGCGATAGTGAGACGC
TGAATAAGGAGTGGCTGCGGGAGCCGGAAGAGACTCCCGCAACGGGTGATTAA

Upstream 100 bases:

>100_bases
AATCTCTCAATTAAACACCGCCGCAAAGTGTAGGGAGTGAAATTAGTGTTGTGAAACGGTAATATTTGATGACTGGTTTC
AAAAATTTTGTAGGCAGACT

Downstream 100 bases:

>100_bases
CGACGATAGTCGCGGAACGGGCCGTCAGCCACGGAGCGGCGTTCAATCAAGCGCGGATGCACTTCAATGGACTGCGGTTC
TTCACGTTTGTTGACGATAC

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITR
QQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMV
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD

Sequences:

>Translated_310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITR
QQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMV
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>Mature_310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITR
QQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMV
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787949, Length=310, Percent_Identity=99.6774193548387, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1786508, Length=285, Percent_Identity=30.1754385964912, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1786713, Length=275, Percent_Identity=30.9090909090909, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082024, Length=249, Percent_Identity=31.3253012048193, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789492, Length=280, Percent_Identity=30, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=33.5260115606936, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35264; Mature: 35264

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEE
AGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCC
VELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLAL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCHHHHHCCCCEEEEEEECCCCEEE
MDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHCC
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLR
HHHHHCHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHC
EPEETPATGD
CCCCCCCCCC
>Mature Secondary Structure
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTA
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEE
AGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCC
VELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLAL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCHHHHHCCCCEEEEEEECCCCEEE
MDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHCC
PTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLR
HHHHHCHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHC
EPEETPATGD
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]