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The map label for this gene is c2 [C]

Identifier: 157159743

GI number: 157159743

Start: 301440

End: 302090

Strand: Reverse

Name: c2 [C]

Synonym: EcHS_A0289

Alternate gene names: 157159743

Gene position: 302090-301440 (Counterclockwise)

Preceding gene: 157159775

Following gene: 157159742

Centisome position: 6.51

GC content: 45.93

Gene sequence:

>651_bases
ATGAATACACAACTGATGGGTGAGCGTATTCGCGCTCGCAGAAAAGAACTCAAGATTAGGCAGGCTGCCCTTGGCAAGAT
GGTTGGCGTGTCTAATGTTGCTATTTCCCAATGGGAGCGATCTGAAACTGAGCCCAATGGCGAAAACCTATTGGCCTTAG
CCAAGGCTTTGCAGTGCTCCCCTGATTACCTGTTGAAAGGAGAGGATAGTCTTTCAAACATTGCCTATCACAGCAGGCAT
GATCCAAGAGGTTCGTATCCTCTAATTAGTTGGGTAAGCGCAGGATGTTGGATGGAAGCTGTAGAGCCATATCATAGGCG
TGCAATAGATAACTGGTACGACACAACGGTAGATTGTTCTGAAGACTCTTTTTGGCTCGACGTTAAAGGCGATTCAATGA
CTGCCCCGGCAGGACTGAGTATTCCTGAGGGGATGATTATTCTCGTCGACCCAGAAGTCGAACCACGTAATGGAAAGCTG
GTAGTCGCCAAACTTGAAGGAGAAAACGAGGCGACATTCAAAAAGTTAGTTATTGATGCCGGTAGAAAATTCCTGAAACC
ACTCAATCCACAATACCCAATGATTGAAATCAATGGGAACTGTAAAATCATTGGCGTTGTCGTTGATGCCAAGCTAGCAA
ACCTTCCTTAA

Upstream 100 bases:

>100_bases
ATAACATCTTTTTTGTACATAGACTCGCTCCGAAATTAAAGAACACTTAAATTATCCACCAAAGGAATCTTAAGTCAAGT
TTATTTAAGATGTCTTAACT

Downstream 100 bases:

>100_bases
GGGGCTTTCGCCCCTTTTTTATTTCCCGTTAAAAATCAAAGACAAACTAAATTCACGCCCATAAAATTAAGTTTTCTTCA
AAAATGCACTTGACCAATAA

Product: P22 repressor protein c2

Products: NA

Alternate protein names: ORF-96 protein [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNTQLMGERIRARRKELKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALAKALQCSPDYLLKGEDSLSNIAYHSRH
DPRGSYPLISWVSAGCWMEAVEPYHRRAIDNWYDTTVDCSEDSFWLDVKGDSMTAPAGLSIPEGMIILVDPEVEPRNGKL
VVAKLEGENEATFKKLVIDAGRKFLKPLNPQYPMIEINGNCKIIGVVVDAKLANLP

Sequences:

>Translated_216_residues
MNTQLMGERIRARRKELKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALAKALQCSPDYLLKGEDSLSNIAYHSRH
DPRGSYPLISWVSAGCWMEAVEPYHRRAIDNWYDTTVDCSEDSFWLDVKGDSMTAPAGLSIPEGMIILVDPEVEPRNGKL
VVAKLEGENEATFKKLVIDAGRKFLKPLNPQYPMIEINGNCKIIGVVVDAKLANLP
>Mature_216_residues
MNTQLMGERIRARRKELKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALAKALQCSPDYLLKGEDSLSNIAYHSRH
DPRGSYPLISWVSAGCWMEAVEPYHRRAIDNWYDTTVDCSEDSFWLDVKGDSMTAPAGLSIPEGMIILVDPEVEPRNGKL
VVAKLEGENEATFKKLVIDAGRKFLKPLNPQYPMIEINGNCKIIGVVVDAKLANLP

Specific function: May control the expression of the integrase and inhibit excision of the mobile element R391, and regulate the expression of other genes as well [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787391, Length=124, Percent_Identity=41.1290322580645, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787853, Length=64, Percent_Identity=54.6875, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF01381 HTH_3; PF00717 Peptidase_S24 [H]

EC number: NA

Molecular weight: Translated: 24038; Mature: 24038

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQLMGERIRARRKELKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALAKALQCS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
PDYLLKGEDSLSNIAYHSRHDPRGSYPLISWVSAGCWMEAVEPYHRRAIDNWYDTTVDCS
CCEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHCHHHHHHHCCCCCCEEECC
EDSFWLDVKGDSMTAPAGLSIPEGMIILVDPEVEPRNGKLVVAKLEGENEATFKKLVIDA
CCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
GRKFLKPLNPQYPMIEINGNCKIIGVVVDAKLANLP
HHHHHCCCCCCCCEEEECCCEEEEEEEEECEECCCC
>Mature Secondary Structure
MNTQLMGERIRARRKELKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALAKALQCS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
PDYLLKGEDSLSNIAYHSRHDPRGSYPLISWVSAGCWMEAVEPYHRRAIDNWYDTTVDCS
CCEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHCHHHHHHHCCCCCCEEECC
EDSFWLDVKGDSMTAPAGLSIPEGMIILVDPEVEPRNGKLVVAKLEGENEATFKKLVIDA
CCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
GRKFLKPLNPQYPMIEINGNCKIIGVVVDAKLANLP
HHHHHCCCCCCCCEEEECCCEEEEEEEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157923; 12193633 [H]