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The map label for this gene is caiE

Identifier: 157159504

GI number: 157159504

Start: 38039

End: 38629

Strand: Reverse

Name: caiE

Synonym: EcHS_A0039

Alternate gene names: 157159504

Gene position: 38629-38039 (Counterclockwise)

Preceding gene: 229220676

Following gene: 157159502

Centisome position: 0.83

GC content: 55.16

Gene sequence:

>591_bases
GTGAGCTATTACGCCTTTGAGGGGTTAATTCCGGTGGTTCACCCGACGGCGTTTGTCCATCCCAGTGCCGTCTTGATTGG
CGATGTGATTGTGGGAGCCGGTGTCTACATCGGCCCACTCGCCTCACTGCGTGGTGACTACGGGCGGTTGATCGTGCAAG
CGGGAGCCAATATTCAGGATGGCTGCATTATGCATGGCTACTGCGACACTGACACCATCGTTGGGGAAAACGGCCATATC
GGGCACGGAGCGATCCTGCATGGTTGTGTGATTGGTCGCGATGCATTGGTCGGGATGAACAGCGTGATTATGGATGGCGC
GGTCATTGGCGAAGAGAGCATTGTTGCCGCCATGAGCTTTGTCAAAGCAGGCTTTCACGGCGAGAAACGCCAGTTGTTGA
TGGGTACGCCAGCCCGCGCTGTACGCAGTGTTAGTGACGACGAGTTACACTGGAAACGGTTGAATACCAAAGAGTATCAG
GATCTTGTCGGGCGCTGTCATGCATCGTTACATGAAACACAGCCACTGAGGCAAATGGAGGAAAATCGCCCCCGTTTGCA
GGGGACGACGGATGTGACGCCTAAACGGTGA

Upstream 100 bases:

>100_bases
TGAAACACTATCCGTCGGTTCTGCATTCGGAGGATGCCATTGAAGGGCCGCTGGCGTTTGCCGAGAAGCGCGATCCGGTG
TGGAAAGGACGTTAACAACC

Downstream 100 bases:

>100_bases
TCTTGCCGGATGCGACCTGGTTGCTGGATAAGATGCTACAACATCGCATCTGGCAAGCAGGACGCCCGGTATCAACGAGA
TAAAATTAACGACGCATACT

Product: carnitine operon protein CaiE

Products: cofactor [C]

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHI
GHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR

Sequences:

>Translated_196_residues
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHI
GHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>Mature_195_residues
SYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIG
HGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQD
LVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR

Specific function: Overproduction of CaiE stimulates the activity of CaiB and CaiD

COG id: COG0663

COG function: function code R; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI87081681, Length=196, Percent_Identity=97.9591836734694, Blast_Score=396, Evalue=1e-112,
Organism=Escherichia coli, GI1787667, Length=196, Percent_Identity=58.6734693877551, Blast_Score=246, Evalue=8e-67,
Organism=Escherichia coli, GI87082240, Length=177, Percent_Identity=31.638418079096, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CAIE_ECO24 (A7ZHC6)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461205.1
- ProteinModelPortal:   A7ZHC6
- SMR:   A7ZHC6
- STRING:   A7ZHC6
- EnsemblBacteria:   EBESCT00000019516
- GeneID:   5587319
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0037
- eggNOG:   COG0663
- GeneTree:   EBGT00050000010015
- HOGENOM:   HBG621238
- OMA:   HIGHGAV
- ProtClustDB:   PRK13627
- BioCyc:   ECOL331111:ECE24377A_0037-MONOMER
- HAMAP:   MF_01525
- InterPro:   IPR011004

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: NA

Molecular weight: Translated: 21157; Mature: 21025

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQD
CCCCCCCCCCHHHCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHEEEEECCCCCCC
GCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSF
CEEEECCCCCCCEECCCCCCCCHHHHHHHHHCCHHHHCCHHHHHCCCCCCHHHHHHHHHH
VKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQME
HHHCCCCCCCEEEECCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHH
ENRPRLQGTTDVTPKR
HCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQD
CCCCCCCCCHHHCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHEEEEECCCCCCC
GCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSF
CEEEECCCCCCCEECCCCCCCCHHHHHHHHHCCHHHHCCHHHHHCCCCCCHHHHHHHHHH
VKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQME
HHHCCCCCCCEEEECCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHH
ENRPRLQGTTDVTPKR
HCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pre-cofactor [C]

Specific reaction: pre-cofactor = cofactor [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA