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The map label for this gene is dctB [H]

Identifier: 156978284

GI number: 156978284

Start: 2162648

End: 2164561

Strand: Reverse

Name: dctB [H]

Synonym: VIBHAR_07091

Alternate gene names: 156978284

Gene position: 2164561-2162648 (Counterclockwise)

Preceding gene: 156978287

Following gene: 156978283

Centisome position: 98.21

GC content: 46.6

Gene sequence:

>1914_bases
ATGCCTTTTGATAACATGGCGTTAAAAACCAGTGAGCCAATCGTGAACCTACTTAACCCCAAAGCTCTGCGCCATTTTTT
GTTGGTCTTGCTCGCCATCGGTCTGGTCGGGCTGATGTTGACACATAAATACGCAACCCAGCATCAACATGATCAGTGGC
AAAGCAAGTTACAAACTCAAGCTTCACAGGTCGCCCAAGAAATCGATTATGAATTGGCAAAGTTTGAGCAAATCCCCAAC
TTACTCAGCCATGATCCAAGATTGCTTGAAGCCGTTAAAGTAGGTAAGCCATCAGAATCGCTCAACTTATTGCTCGCCGA
TTGGTTAGCGCAAAGCCTCGCTGACACTATCTATGTGCACGACAAAACCGGCTTAGTTATCGCATCTAGTAACTACCAGC
AAGACGACAGCTTTGTGGGCTCGAACTTTGCCTTCCGTCCATACTTTCAACACGCTTTAAATGGGGAGAAAGCTCAGTAC
GTTGCTCTTGGCGTACGTTCCAATAAACGCGGCTATTTCTTCTCGTCCCCTCTTTGGGTTGAGGGCAAAGTCGCAGGCGT
GATTACCGTTAAAGTGAACCTAGAGCAGTTAGAACAAAGATTGGCACAAGACGATGGCGGCTTGCTGGTTACAGGTGTGC
ACGATGTCGTCTTCATGAGTAACTTGCCCGATTGGCGCTATCGCGCGCTTTTCCCGTTATCCGAAGATGCGAAAGAAGAA
CTCAATCAAACTCAACAATATGGCGATACCCTGCCGCAATACAGAGGCGAGTTGACTGGGCAAAGTGGCGCGACGCAGTT
TGAGAACAATCAGCTATTGGTTTCACCCAACTACCTCGCTTACGCAACAAACTTATTCGACAAAGGTTTTCGTGTTGTCG
CTCTGATTAGCCAACAAGAAGTGTTTGCTGCGGTATTGCAAGCGGATGTGATTTACCTTTTGCTGTATTCGCTCGTTGGC
CTAATAGCATTAGCGTGGTTTCAAATGTTGGTCAACAAAGCACGATTAGCAAATATGAATACAAACTTGGAAGAAAAGGT
CACGGAACGCACCATAGTACTGAGCCAAGCCAACCACCAGCTGCAACAAACCGTGCACCAATATGAACAGAGTCAGCAAG
CGCTCAAGCAAACCCAACAAGAGCTCACTCAAGCCGCGAAACTCGCACTACTGGGCGAGCTGTCTGCCAGCATCAATCAT
GAAATCAACCAACCACTTGCTGCACTTCGCACCTATACAGAAAACTCTCAACGTTTGATGGCGATGGAACGCTACCCAAT
GGTGACAGATAATCTCGGCAAAATGCTTTATCTCAATGACACCATTGCCGAAGTCATTGCTCGTTTGAAAGTCTTTACGC
GCAAAACGGACAAGAATTCGCACAATGAGGTGTCCGTGCTACACGACGCGGTACATAACGCGACGCGCATTCTGAGCAGC
AAGCTGATCAAACAAGGGGTGACGCTAAAAGAGCCAAACATTGAATGCAACGTGAAACTCGCCATTCATAGCGTCGAGCT
AGAGCAAGTACTGATAAATCTCTTCCATAATGCAGCCCAAGCGATGGAAGGACACTGTGTCGATCCACAAATTTCGATCG
CGATACAATGCAATGAAAGCAACTGCGATATTCTGATTTCCGACAACGGACCAGGTATGTCAGAACAAGCATTAGCCAAA
GTATTCGATCCATTTTTCACCACTAAACCAGAAGGGCTTGGGCTGGGTTTAACCATTTCAAAACGTATTTTAGAAAGCTA
TCAAGGCTCTCTCAGTGCTTACAATCACAATACTTACAATCATAGTGCTTTCAGTGATATGGATACGCAATCCCAGCACT
CAGGCGGCATGACCTTTATTGTCAGCGTGCCTTTAGTCCCACTTCATCCTGCAGAGGAACACTCTCATGCATAA

Upstream 100 bases:

>100_bases
TGTGCGCCCGATACTAAGGAAATACAAGGACAGCAAGCAAGAACCCTGATTGCAGTTTTGTGCTGTGTCACGTTGTCGCA
GCAGCTCACAACATCATTAA

Downstream 100 bases:

>100_bases
TCCCGTTTTCTTTGTTGATGATGAACCCCATATCCGTGATGCGGTTACTCAAGCGCTATTAATCGAAGGGATTGACGTCA
CTTGCTTTCCAAACGCAGTT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MPFDNMALKTSEPIVNLLNPKALRHFLLVLLAIGLVGLMLTHKYATQHQHDQWQSKLQTQASQVAQEIDYELAKFEQIPN
LLSHDPRLLEAVKVGKPSESLNLLLADWLAQSLADTIYVHDKTGLVIASSNYQQDDSFVGSNFAFRPYFQHALNGEKAQY
VALGVRSNKRGYFFSSPLWVEGKVAGVITVKVNLEQLEQRLAQDDGGLLVTGVHDVVFMSNLPDWRYRALFPLSEDAKEE
LNQTQQYGDTLPQYRGELTGQSGATQFENNQLLVSPNYLAYATNLFDKGFRVVALISQQEVFAAVLQADVIYLLLYSLVG
LIALAWFQMLVNKARLANMNTNLEEKVTERTIVLSQANHQLQQTVHQYEQSQQALKQTQQELTQAAKLALLGELSASINH
EINQPLAALRTYTENSQRLMAMERYPMVTDNLGKMLYLNDTIAEVIARLKVFTRKTDKNSHNEVSVLHDAVHNATRILSS
KLIKQGVTLKEPNIECNVKLAIHSVELEQVLINLFHNAAQAMEGHCVDPQISIAIQCNESNCDILISDNGPGMSEQALAK
VFDPFFTTKPEGLGLGLTISKRILESYQGSLSAYNHNTYNHSAFSDMDTQSQHSGGMTFIVSVPLVPLHPAEEHSHA

Sequences:

>Translated_637_residues
MPFDNMALKTSEPIVNLLNPKALRHFLLVLLAIGLVGLMLTHKYATQHQHDQWQSKLQTQASQVAQEIDYELAKFEQIPN
LLSHDPRLLEAVKVGKPSESLNLLLADWLAQSLADTIYVHDKTGLVIASSNYQQDDSFVGSNFAFRPYFQHALNGEKAQY
VALGVRSNKRGYFFSSPLWVEGKVAGVITVKVNLEQLEQRLAQDDGGLLVTGVHDVVFMSNLPDWRYRALFPLSEDAKEE
LNQTQQYGDTLPQYRGELTGQSGATQFENNQLLVSPNYLAYATNLFDKGFRVVALISQQEVFAAVLQADVIYLLLYSLVG
LIALAWFQMLVNKARLANMNTNLEEKVTERTIVLSQANHQLQQTVHQYEQSQQALKQTQQELTQAAKLALLGELSASINH
EINQPLAALRTYTENSQRLMAMERYPMVTDNLGKMLYLNDTIAEVIARLKVFTRKTDKNSHNEVSVLHDAVHNATRILSS
KLIKQGVTLKEPNIECNVKLAIHSVELEQVLINLFHNAAQAMEGHCVDPQISIAIQCNESNCDILISDNGPGMSEQALAK
VFDPFFTTKPEGLGLGLTISKRILESYQGSLSAYNHNTYNHSAFSDMDTQSQHSGGMTFIVSVPLVPLHPAEEHSHA
>Mature_636_residues
PFDNMALKTSEPIVNLLNPKALRHFLLVLLAIGLVGLMLTHKYATQHQHDQWQSKLQTQASQVAQEIDYELAKFEQIPNL
LSHDPRLLEAVKVGKPSESLNLLLADWLAQSLADTIYVHDKTGLVIASSNYQQDDSFVGSNFAFRPYFQHALNGEKAQYV
ALGVRSNKRGYFFSSPLWVEGKVAGVITVKVNLEQLEQRLAQDDGGLLVTGVHDVVFMSNLPDWRYRALFPLSEDAKEEL
NQTQQYGDTLPQYRGELTGQSGATQFENNQLLVSPNYLAYATNLFDKGFRVVALISQQEVFAAVLQADVIYLLLYSLVGL
IALAWFQMLVNKARLANMNTNLEEKVTERTIVLSQANHQLQQTVHQYEQSQQALKQTQQELTQAAKLALLGELSASINHE
INQPLAALRTYTENSQRLMAMERYPMVTDNLGKMLYLNDTIAEVIARLKVFTRKTDKNSHNEVSVLHDAVHNATRILSSK
LIKQGVTLKEPNIECNVKLAIHSVELEQVLINLFHNAAQAMEGHCVDPQISIAIQCNESNCDILISDNGPGMSEQALAKV
FDPFFTTKPEGLGLGLTISKRILESYQGSLSAYNHNTYNHSAFSDMDTQSQHSGGMTFIVSVPLVPLHPAEEHSHA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=32.8125, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=26.5917602996255, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71178; Mature: 71047

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDNMALKTSEPIVNLLNPKALRHFLLVLLAIGLVGLMLTHKYATQHQHDQWQSKLQTQ
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ASQVAQEIDYELAKFEQIPNLLSHDPRLLEAVKVGKPSESLNLLLADWLAQSLADTIYVH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEE
DKTGLVIASSNYQQDDSFVGSNFAFRPYFQHALNGEKAQYVALGVRSNKRGYFFSSPLWV
CCCCEEEEECCCCCCCCCCCCCCEECHHHHHHCCCCCCEEEEEEEECCCCCEEECCCEEE
EGKVAGVITVKVNLEQLEQRLAQDDGGLLVTGVHDVVFMSNLPDWRYRALFPLSEDAKEE
CCEEEEEEEEEECHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCCCEEEECCCCHHHHHH
LNQTQQYGDTLPQYRGELTGQSGATQFENNQLLVSPNYLAYATNLFDKGFRVVALISQQE
HHHHHHHHCCHHHHHCCCCCCCCCCEECCCEEEECCCHHHHHHHHHHCCCEEEEEECHHH
VFAAVLQADVIYLLLYSLVGLIALAWFQMLVNKARLANMNTNLEEKVTERTIVLSQANHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LQQTVHQYEQSQQALKQTQQELTQAAKLALLGELSASINHEINQPLAALRTYTENSQRLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AMERYPMVTDNLGKMLYLNDTIAEVIARLKVFTRKTDKNSHNEVSVLHDAVHNATRILSS
HHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KLIKQGVTLKEPNIECNVKLAIHSVELEQVLINLFHNAAQAMEGHCVDPQISIAIQCNES
HHHHCCCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
NCDILISDNGPGMSEQALAKVFDPFFTTKPEGLGLGLTISKRILESYQGSLSAYNHNTYN
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHCCCCEECCCCCCC
HSAFSDMDTQSQHSGGMTFIVSVPLVPLHPAEEHSHA
CCCCCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCC
>Mature Secondary Structure 
PFDNMALKTSEPIVNLLNPKALRHFLLVLLAIGLVGLMLTHKYATQHQHDQWQSKLQTQ
CCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ASQVAQEIDYELAKFEQIPNLLSHDPRLLEAVKVGKPSESLNLLLADWLAQSLADTIYVH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEE
DKTGLVIASSNYQQDDSFVGSNFAFRPYFQHALNGEKAQYVALGVRSNKRGYFFSSPLWV
CCCCEEEEECCCCCCCCCCCCCCEECHHHHHHCCCCCCEEEEEEEECCCCCEEECCCEEE
EGKVAGVITVKVNLEQLEQRLAQDDGGLLVTGVHDVVFMSNLPDWRYRALFPLSEDAKEE
CCEEEEEEEEEECHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCCCEEEECCCCHHHHHH
LNQTQQYGDTLPQYRGELTGQSGATQFENNQLLVSPNYLAYATNLFDKGFRVVALISQQE
HHHHHHHHCCHHHHHCCCCCCCCCCEECCCEEEECCCHHHHHHHHHHCCCEEEEEECHHH
VFAAVLQADVIYLLLYSLVGLIALAWFQMLVNKARLANMNTNLEEKVTERTIVLSQANHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LQQTVHQYEQSQQALKQTQQELTQAAKLALLGELSASINHEINQPLAALRTYTENSQRLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AMERYPMVTDNLGKMLYLNDTIAEVIARLKVFTRKTDKNSHNEVSVLHDAVHNATRILSS
HHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KLIKQGVTLKEPNIECNVKLAIHSVELEQVLINLFHNAAQAMEGHCVDPQISIAIQCNES
HHHHCCCCEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
NCDILISDNGPGMSEQALAKVFDPFFTTKPEGLGLGLTISKRILESYQGSLSAYNHNTYN
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHCCCCEECCCCCCC
HSAFSDMDTQSQHSGGMTFIVSVPLVPLHPAEEHSHA
CCCCCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]