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The map label for this gene is aprE [H]

Identifier: 156978282

GI number: 156978282

Start: 2159925

End: 2161385

Strand: Reverse

Name: aprE [H]

Synonym: VIBHAR_07089

Alternate gene names: 156978282

Gene position: 2161385-2159925 (Counterclockwise)

Preceding gene: 156978283

Following gene: 156978281

Centisome position: 98.07

GC content: 47.23

Gene sequence:

>1461_bases
ATGCTGACATGCTCGGTTAATAATAATAAGATCAAAAAGATAAACCGTCTTTATAGAACAAGGAATGTGATGAGCCGAGA
CAACTACAACAAACTGAGCAGCGACGAGCTAGACTTTGTTGATGACAAAACCGCTGCTTTGCTCTTAAACACGCCAAATA
GTGCCCGCTTAATGCTGTGGGTGATGGCGCTGTTTTTTGTAGCGGCCATTGGCTGGGCATCTTGGGCTGAGATCGACAAA
GTGACCGTAGGCCAAGGCAAAGTCATTCCATCTTCTCAAATCCAAGTGGTGCAGAACTTAGAAGGTGGCTTGGTCAAAAA
GATATTAGTTAAAGAGGGTCAAAAAGTTCAGAAAGATCAGCAGTTGCTGCTGATTGACGACACCCGCTTCCGCTCTGACT
TTCGTGAACGTGAACAGCAAGTTGCCAACTTAACCGCTTCAGTACTGCATCTCTCAGCCTCAATCAACAGTGTCGAAGTC
AATCGTGATTTTGACGACAGTAACTGGGAAAAGAATGTCGTTATCGACTATGGCAAACTGACGTTCCCACCGATACTTGA
AGAGAACCGCCCTCGCCTGACTCAACGTCAGAAAGCAGAATACCGCGAAGACTTGGATAACCTGCGCAGCCAAATTTCGG
TCATAGACCAACAAGTTAAGCAGAAACAACAGGATTTGGTGGAGATTCAAGCGCGTGTGAGCAACCTTCGTCAAAGCTAT
CGTTATGCAAAGAAAGAACTGGATATCACCAAACCTCTGGCTGATGAAGGCGTCGTACCTAGAATTGAACTCTTAAAGCT
TCAACGTCAGGTGAACGACACCCGTCGAGAAATGACGTCTAGCGAGTTGAAGATCCCTGTCATCAAATCGGGCATCCGTG
AATCGATGCTCAACCGTATCGATGTCGCGTTGAAATTCCGCTCCGAGCAACAAGAAAAACTCAACAGCACACAAGACCAG
CTCTCAGCACTAGTCGAATCAGCGGTAGGCTTGGAAGACCGAGTAAACCGAACTGTGGTGGTTTCTCCAGTAACGGGCAC
CATCAAGACATTGAACGTCAACACCGTCGGTGGCGTTATCCAGCCGGGTATGGACATCGTAGAAATCGTGCCGACCGAAG
ACACCTTATTAGTGGAAGCGAAGATCGCGCCGAAGGACATCGCTTTCTTGCGTCCAGATCTTCATGCGATTGTGAAATTC
ACTGCGTACGACTTCACTAAATACGGCGGCTTAGAAGGAGAGTTGGAACACATTAGTGCCGACACCACACAAGACGAAGA
AGGCAACAGCTTCTACATCGTCCGTATACGCACAGAGAAAACCAGTTTCGGACAAGATGCGGACTTACCTATCATTCCAG
GTATGACGGCATCTGTTGATATCATCACAGGGAAACGAACGGTACTAGAATATCTACTCAAGCCGATTTTGAGCGCCAAA
ACCAACGCACTGAAGGAGTAA

Upstream 100 bases:

>100_bases
TTGTATGACAAACTAAAAAAACATCAGTTGGACAAAACACAGTTCAAGGCATAGTAAACAAAGGGATGCTTACCCTTTCA
CACATTTTTATTAACCGAGC

Downstream 100 bases:

>100_bases
GTGTTTGCAAGGTACAAACAATGTGTTCTTACATGATGACAAGTGGTTAAATAAAAAGCACTTTTCTCACCAATGAACCC
ATTTCAAGGGTACACTTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MLTCSVNNNKIKKINRLYRTRNVMSRDNYNKLSSDELDFVDDKTAALLLNTPNSARLMLWVMALFFVAAIGWASWAEIDK
VTVGQGKVIPSSQIQVVQNLEGGLVKKILVKEGQKVQKDQQLLLIDDTRFRSDFREREQQVANLTASVLHLSASINSVEV
NRDFDDSNWEKNVVIDYGKLTFPPILEENRPRLTQRQKAEYREDLDNLRSQISVIDQQVKQKQQDLVEIQARVSNLRQSY
RYAKKELDITKPLADEGVVPRIELLKLQRQVNDTRREMTSSELKIPVIKSGIRESMLNRIDVALKFRSEQQEKLNSTQDQ
LSALVESAVGLEDRVNRTVVVSPVTGTIKTLNVNTVGGVIQPGMDIVEIVPTEDTLLVEAKIAPKDIAFLRPDLHAIVKF
TAYDFTKYGGLEGELEHISADTTQDEEGNSFYIVRIRTEKTSFGQDADLPIIPGMTASVDIITGKRTVLEYLLKPILSAK
TNALKE

Sequences:

>Translated_486_residues
MLTCSVNNNKIKKINRLYRTRNVMSRDNYNKLSSDELDFVDDKTAALLLNTPNSARLMLWVMALFFVAAIGWASWAEIDK
VTVGQGKVIPSSQIQVVQNLEGGLVKKILVKEGQKVQKDQQLLLIDDTRFRSDFREREQQVANLTASVLHLSASINSVEV
NRDFDDSNWEKNVVIDYGKLTFPPILEENRPRLTQRQKAEYREDLDNLRSQISVIDQQVKQKQQDLVEIQARVSNLRQSY
RYAKKELDITKPLADEGVVPRIELLKLQRQVNDTRREMTSSELKIPVIKSGIRESMLNRIDVALKFRSEQQEKLNSTQDQ
LSALVESAVGLEDRVNRTVVVSPVTGTIKTLNVNTVGGVIQPGMDIVEIVPTEDTLLVEAKIAPKDIAFLRPDLHAIVKF
TAYDFTKYGGLEGELEHISADTTQDEEGNSFYIVRIRTEKTSFGQDADLPIIPGMTASVDIITGKRTVLEYLLKPILSAK
TNALKE
>Mature_486_residues
MLTCSVNNNKIKKINRLYRTRNVMSRDNYNKLSSDELDFVDDKTAALLLNTPNSARLMLWVMALFFVAAIGWASWAEIDK
VTVGQGKVIPSSQIQVVQNLEGGLVKKILVKEGQKVQKDQQLLLIDDTRFRSDFREREQQVANLTASVLHLSASINSVEV
NRDFDDSNWEKNVVIDYGKLTFPPILEENRPRLTQRQKAEYREDLDNLRSQISVIDQQVKQKQQDLVEIQARVSNLRQSY
RYAKKELDITKPLADEGVVPRIELLKLQRQVNDTRREMTSSELKIPVIKSGIRESMLNRIDVALKFRSEQQEKLNSTQDQ
LSALVESAVGLEDRVNRTVVVSPVTGTIKTLNVNTVGGVIQPGMDIVEIVPTEDTLLVEAKIAPKDIAFLRPDLHAIVKF
TAYDFTKYGGLEGELEHISADTTQDEEGNSFYIVRIRTEKTSFGQDADLPIIPGMTASVDIITGKRTVLEYLLKPILSAK
TNALKE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 54941; Mature: 54941

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTCSVNNNKIKKINRLYRTRNVMSRDNYNKLSSDELDFVDDKTAALLLNTPNSARLMLW
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
VMALFFVAAIGWASWAEIDKVTVGQGKVIPSSQIQVVQNLEGGLVKKILVKEGQKVQKDQ
HHHHHHHHHHCCHHHHHHCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
QLLLIDDTRFRSDFREREQQVANLTASVLHLSASINSVEVNRDFDDSNWEKNVVIDYGKL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCC
TFPPILEENRPRLTQRQKAEYREDLDNLRSQISVIDQQVKQKQQDLVEIQARVSNLRQSY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYAKKELDITKPLADEGVVPRIELLKLQRQVNDTRREMTSSELKIPVIKSGIRESMLNRI
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVALKFRSEQQEKLNSTQDQLSALVESAVGLEDRVNRTVVVSPVTGTIKTLNVNTVGGVI
HHHHHHCCHHHHHHCCHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCEEEEEECCCCCHH
QPGMDIVEIVPTEDTLLVEAKIAPKDIAFLRPDLHAIVKFTAYDFTKYGGLEGELEHISA
CCCCCEEEEECCCCEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCCC
DTTQDEEGNSFYIVRIRTEKTSFGQDADLPIIPGMTASVDIITGKRTVLEYLLKPILSAK
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
TNALKE
HHHCCC
>Mature Secondary Structure
MLTCSVNNNKIKKINRLYRTRNVMSRDNYNKLSSDELDFVDDKTAALLLNTPNSARLMLW
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
VMALFFVAAIGWASWAEIDKVTVGQGKVIPSSQIQVVQNLEGGLVKKILVKEGQKVQKDQ
HHHHHHHHHHCCHHHHHHCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
QLLLIDDTRFRSDFREREQQVANLTASVLHLSASINSVEVNRDFDDSNWEKNVVIDYGKL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCC
TFPPILEENRPRLTQRQKAEYREDLDNLRSQISVIDQQVKQKQQDLVEIQARVSNLRQSY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYAKKELDITKPLADEGVVPRIELLKLQRQVNDTRREMTSSELKIPVIKSGIRESMLNRI
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVALKFRSEQQEKLNSTQDQLSALVESAVGLEDRVNRTVVVSPVTGTIKTLNVNTVGGVI
HHHHHHCCHHHHHHCCHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCEEEEEECCCCCHH
QPGMDIVEIVPTEDTLLVEAKIAPKDIAFLRPDLHAIVKFTAYDFTKYGGLEGELEHISA
CCCCCEEEEECCCCEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCCC
DTTQDEEGNSFYIVRIRTEKTSFGQDADLPIIPGMTASVDIITGKRTVLEYLLKPILSAK
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
TNALKE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]