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The map label for this gene is ribA [H]

Identifier: 156978235

GI number: 156978235

Start: 2115294

End: 2115851

Strand: Reverse

Name: ribA [H]

Synonym: VIBHAR_07040

Alternate gene names: 156978235

Gene position: 2115851-2115294 (Counterclockwise)

Preceding gene: 156978236

Following gene: 156978233

Centisome position: 96.0

GC content: 44.44

Gene sequence:

>558_bases
ATGTTTATCATGCATGGTTTTATCGAGAACGCGACAGGAAAAGAGCACTTAGCGCTTGTGTATGGTGACCTAGCCAGAAA
TGAAGCCCCGTTGATTCGTTTGCACTCAGAGTGTTTAACCAGCGATGCGCTGCTCAGTACGCGTTGTGATTGTGGATTCC
AGATTAATCGTACGTTGCAAAATATTGTCGAAGAAGGCTGTGGTGTGCTGCTCTATTTGTGCCAAGAGGGTAGGGGAATT
GGCTTCATCAATAAGATTCGTGCGTATCACTTACAAGATGAAGGCGCAGACACTGTCGAAGCCAATGAGCGCCTGGGCTT
TGCTGCTGATATGCGTGATTACGCGTTTTATAAAGGGATATTGGGATATCTTGGAATCAATAAAGTACGTTTGATGACCA
ACAATCTACGCAAGCTTGCAGCGTTGAAGAAGGTAAACATCAATGTGGTTGAGCGGGTACCACTGCAAGAAAGCAATAAC
CTAAATCAACACTACCTTCAAACCAAAGCCAATAGGCTTGGCCACATGTTAGACGCCAAATTTGTCGAACAAGATTAA

Upstream 100 bases:

>100_bases
AGGAGAGATTTTGATGAACGTACGTGCAGAGCTAAAGCATGTAAAGCCATATAACTTGGTGCGTTTTGTCGATAAAGCCA
AACTACCTACCCAATGAGGC

Downstream 100 bases:

>100_bases
GCACTCTAACAAGATTAATCGCAGAGACGATATAAAAATCAAATCGCCAGCTAATCGATGCTGGCGGTTTTTGTTACAGT
TTGGGCGTAAGCGGCTAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MFIMHGFIENATGKEHLALVYGDLARNEAPLIRLHSECLTSDALLSTRCDCGFQINRTLQNIVEEGCGVLLYLCQEGRGI
GFINKIRAYHLQDEGADTVEANERLGFAADMRDYAFYKGILGYLGINKVRLMTNNLRKLAALKKVNINVVERVPLQESNN
LNQHYLQTKANRLGHMLDAKFVEQD

Sequences:

>Translated_185_residues
MFIMHGFIENATGKEHLALVYGDLARNEAPLIRLHSECLTSDALLSTRCDCGFQINRTLQNIVEEGCGVLLYLCQEGRGI
GFINKIRAYHLQDEGADTVEANERLGFAADMRDYAFYKGILGYLGINKVRLMTNNLRKLAALKKVNINVVERVPLQESNN
LNQHYLQTKANRLGHMLDAKFVEQD
>Mature_185_residues
MFIMHGFIENATGKEHLALVYGDLARNEAPLIRLHSECLTSDALLSTRCDCGFQINRTLQNIVEEGCGVLLYLCQEGRGI
GFINKIRAYHLQDEGADTVEANERLGFAADMRDYAFYKGILGYLGINKVRLMTNNLRKLAALKKVNINVVERVPLQESNN
LNQHYLQTKANRLGHMLDAKFVEQD

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=178, Percent_Identity=57.8651685393258, Blast_Score=206, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6319438, Length=169, Percent_Identity=42.603550295858, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 20901; Mature: 20901

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIMHGFIENATGKEHLALVYGDLARNEAPLIRLHSECLTSDALLSTRCDCGFQINRTLQ
CEEEECCCCCCCCCCEEEEEEEHHCCCCCCCEEEHHHHHCHHHHHHHCCCCCCCHHHHHH
NIVEEGCGVLLYLCQEGRGIGFINKIRAYHLQDEGADTVEANERLGFAADMRDYAFYKGI
HHHHHCCCEEEEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGYLGINKVRLMTNNLRKLAALKKVNINVVERVPLQESNNLNQHYLQTKANRLGHMLDAK
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
FVEQD
HCCCC
>Mature Secondary Structure
MFIMHGFIENATGKEHLALVYGDLARNEAPLIRLHSECLTSDALLSTRCDCGFQINRTLQ
CEEEECCCCCCCCCCEEEEEEEHHCCCCCCCEEEHHHHHCHHHHHHHCCCCCCCHHHHHH
NIVEEGCGVLLYLCQEGRGIGFINKIRAYHLQDEGADTVEANERLGFAADMRDYAFYKGI
HHHHHCCCEEEEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LGYLGINKVRLMTNNLRKLAALKKVNINVVERVPLQESNNLNQHYLQTKANRLGHMLDAK
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
FVEQD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA