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The map label for this gene is lolE [C]

Identifier: 156978223

GI number: 156978223

Start: 2103980

End: 2105248

Strand: Reverse

Name: lolE [C]

Synonym: VIBHAR_07028

Alternate gene names: 156978223

Gene position: 2105248-2103980 (Counterclockwise)

Preceding gene: 156978224

Following gene: 156978222

Centisome position: 95.52

GC content: 49.01

Gene sequence:

>1269_bases
ATGGGCAAGCTAATTCCCGTTTCTGTTCGCCTTGCTTGGTTGAACCTGCAACGCAATCGCCGCCGCAGTTTGTTGTCGAT
GCTGATCATCGCCATTGCCGTGTTTGCCTTAACCAGTGCGGGTGGTTTTGGTCTGTACACCTACGACAGTTTGAAAGAGT
CAACAGCACGTGACACGGGGCATCTGACGTTAACCACGCCGGGTTACTTCGCCAAAGAAGAAGAGATGCCGCTGAGTAAC
GGTTTAACTCACGCCGACGACATCACCAAGCAATTGATTGGGTTGAATGAAGTGCGAGGCGTGCAGCCACGAGTTGAGTT
CAGCGGCTTGATTTCCAACGGCAACAAATCCTCGATTTTTATCGGCATTGGTGTGAACGAACGCGAATTCGATATGAAAG
GACCGTTTTTGGATGTACGCGAAGGGCAGACGCTGTCCAATATTCATGCATTGCGTTATGACCCAGCAGAACCAGAAGTG
ATGCTCGGTGTTGATTTGGCGAACAACCTAAGCGTGCACGTTGGCGATTGGATTACCTTGCTGGCGACCACAACCGACGG
TGCATTGAACGCGTATGACTTCAAAGTTCGTGGCATCTATTCAACCGGCGTACCTGAGCTTGATAAACGCCAACTGTACG
TGCATATCAACAGCGCGCAATCGCTGCTCGGTTCAGACAAAGTCAGTGCGTTATCTGTCTTCCTGTTCGACACCAGTTTA
ACTAACCAAGTCGAGCAACAAGTGGCTTCGGTTCTGAGTAAGAATAAACAGAACTTTGGTGATCAAGATATTGAGATTAC
GCCTTGGCAAGAACGTGCGTTCTTCTATCTCAAAGTGAAAGGTTTGTACGACCGTATCTTTGGCATCATGGGCGCAGTAA
TGGCGTTAGTGGTCTTTGTTGCGCTGTTCAACACAATGACCATGTCGGTCACCGAGCGTACACGTGAAATCGGCACATTA
TCAGCACTTGGTAGCTACCCTCGTGAAATCATTGCTGGGTTCTTGCGCGAAGCAGGGTTACTTGCGGTGATTGGCAGTTT
AATCGGTGCTTTGTTTACTGGGTTAGTTACCGTCTTACTGATGGTAGTGGATGTGCAAATGCCGCCACCGCCAGGACGTA
CAGAAGGTTATCCATTGACGATTTACTTTTCTTGGGAGCTGGTGGCTGTTGCAGGATTCGCAGTATTGATGATTTGTTTG
GTTGCGGCGTTTTTCTCGGCGCGCAAAGGGGTGAACAAGCCAATTACGGAGGCACTGATTTATGTTTAA

Upstream 100 bases:

>100_bases
TCGCTACACACGACCCTCGAATGGCATCCCGCTGCGATCGAACCATTGAGTTGGTAGATGGCAAGATTACCCAAACGGAC
GCGAGTGTGGAGGAGGTTTC

Downstream 100 bases:

>100_bases
TTTCAAATCACTATTACCAATTGCATTGCTGACGGTAACTGGCGTTGCAAGCATGAATGCCAGTGCTAATGAAACACCGC
TAGATGCACAGCAAGTCGCG

Product: efflux ABC transporter ATP-binding/permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MGKLIPVSVRLAWLNLQRNRRRSLLSMLIIAIAVFALTSAGGFGLYTYDSLKESTARDTGHLTLTTPGYFAKEEEMPLSN
GLTHADDITKQLIGLNEVRGVQPRVEFSGLISNGNKSSIFIGIGVNEREFDMKGPFLDVREGQTLSNIHALRYDPAEPEV
MLGVDLANNLSVHVGDWITLLATTTDGALNAYDFKVRGIYSTGVPELDKRQLYVHINSAQSLLGSDKVSALSVFLFDTSL
TNQVEQQVASVLSKNKQNFGDQDIEITPWQERAFFYLKVKGLYDRIFGIMGAVMALVVFVALFNTMTMSVTERTREIGTL
SALGSYPREIIAGFLREAGLLAVIGSLIGALFTGLVTVLLMVVDVQMPPPPGRTEGYPLTIYFSWELVAVAGFAVLMICL
VAAFFSARKGVNKPITEALIYV

Sequences:

>Translated_422_residues
MGKLIPVSVRLAWLNLQRNRRRSLLSMLIIAIAVFALTSAGGFGLYTYDSLKESTARDTGHLTLTTPGYFAKEEEMPLSN
GLTHADDITKQLIGLNEVRGVQPRVEFSGLISNGNKSSIFIGIGVNEREFDMKGPFLDVREGQTLSNIHALRYDPAEPEV
MLGVDLANNLSVHVGDWITLLATTTDGALNAYDFKVRGIYSTGVPELDKRQLYVHINSAQSLLGSDKVSALSVFLFDTSL
TNQVEQQVASVLSKNKQNFGDQDIEITPWQERAFFYLKVKGLYDRIFGIMGAVMALVVFVALFNTMTMSVTERTREIGTL
SALGSYPREIIAGFLREAGLLAVIGSLIGALFTGLVTVLLMVVDVQMPPPPGRTEGYPLTIYFSWELVAVAGFAVLMICL
VAAFFSARKGVNKPITEALIYV
>Mature_421_residues
GKLIPVSVRLAWLNLQRNRRRSLLSMLIIAIAVFALTSAGGFGLYTYDSLKESTARDTGHLTLTTPGYFAKEEEMPLSNG
LTHADDITKQLIGLNEVRGVQPRVEFSGLISNGNKSSIFIGIGVNEREFDMKGPFLDVREGQTLSNIHALRYDPAEPEVM
LGVDLANNLSVHVGDWITLLATTTDGALNAYDFKVRGIYSTGVPELDKRQLYVHINSAQSLLGSDKVSALSVFLFDTSLT
NQVEQQVASVLSKNKQNFGDQDIEITPWQERAFFYLKVKGLYDRIFGIMGAVMALVVFVALFNTMTMSVTERTREIGTLS
ALGSYPREIIAGFLREAGLLAVIGSLIGALFTGLVTVLLMVVDVQMPPPPGRTEGYPLTIYFSWELVAVAGFAVLMICLV
AAFFSARKGVNKPITEALIYV

Specific function: Part Of An ATP-Dependent Transport System Lolcde Responsible For The Release Of Lipoproteins Targeted To The Outer Membrane From The Inner Membrane. Such A Release Is Dependent Of The Sorting-Signal (Absence Of An Asp At Position 2 Of The Mature Lipoprot

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46248; Mature: 46117

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLIPVSVRLAWLNLQRNRRRSLLSMLIIAIAVFALTSAGGFGLYTYDSLKESTARDTG
CCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCC
HLTLTTPGYFAKEEEMPLSNGLTHADDITKQLIGLNEVRGVQPRVEFSGLISNGNKSSIF
CEEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHCHHHHCCCCCCCHHHHEECCCCCCEEE
IGIGVNEREFDMKGPFLDVREGQTLSNIHALRYDPAEPEVMLGVDLANNLSVHVGDWITL
EEECCCCCCCCCCCCEEECCCCCCHHHEEEEECCCCCCCEEEEEEECCCCEEEECCEEEE
LATTTDGALNAYDFKVRGIYSTGVPELDKRQLYVHINSAQSLLGSDKVSALSVFLFDTSL
EEECCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEECCHHHHHCCCCHHEEEEEEECCHH
TNQVEQQVASVLSKNKQNFGDQDIEITPWQERAFFYLKVKGLYDRIFGIMGAVMALVVFV
HHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
ALFNTMTMSVTERTREIGTLSALGSYPREIIAGFLREAGLLAVIGSLIGALFTGLVTVLL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MVVDVQMPPPPGRTEGYPLTIYFSWELVAVAGFAVLMICLVAAFFSARKGVNKPITEALI
HHHHCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YV
CC
>Mature Secondary Structure 
GKLIPVSVRLAWLNLQRNRRRSLLSMLIIAIAVFALTSAGGFGLYTYDSLKESTARDTG
CCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCC
HLTLTTPGYFAKEEEMPLSNGLTHADDITKQLIGLNEVRGVQPRVEFSGLISNGNKSSIF
CEEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHCHHHHCCCCCCCHHHHEECCCCCCEEE
IGIGVNEREFDMKGPFLDVREGQTLSNIHALRYDPAEPEVMLGVDLANNLSVHVGDWITL
EEECCCCCCCCCCCCEEECCCCCCHHHEEEEECCCCCCCEEEEEEECCCCEEEECCEEEE
LATTTDGALNAYDFKVRGIYSTGVPELDKRQLYVHINSAQSLLGSDKVSALSVFLFDTSL
EEECCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEECCHHHHHCCCCHHEEEEEEECCHH
TNQVEQQVASVLSKNKQNFGDQDIEITPWQERAFFYLKVKGLYDRIFGIMGAVMALVVFV
HHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
ALFNTMTMSVTERTREIGTLSALGSYPREIIAGFLREAGLLAVIGSLIGALFTGLVTVLL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MVVDVQMPPPPGRTEGYPLTIYFSWELVAVAGFAVLMICLVAAFFSARKGVNKPITEALI
HHHHCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]