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The map label for this gene is galR [H]

Identifier: 156978138

GI number: 156978138

Start: 2038130

End: 2039134

Strand: Reverse

Name: galR [H]

Synonym: VIBHAR_06943

Alternate gene names: 156978138

Gene position: 2039134-2038130 (Counterclockwise)

Preceding gene: 156978139

Following gene: 156978137

Centisome position: 92.52

GC content: 47.76

Gene sequence:

>1005_bases
GTGGCGACGATTAAAGATGTGTCTGAATACGCTGGCGTTTCTCAAGCGACCGTTTCTAGAGTCATTAACGGCACTTGCCG
CGTTAGCCATGACAAAAAGCTTAAAGTCGAAAAAGCGATCAAAGAGTTAGGATATCGTCCAAACTCTATTGCACAGGCAT
TAGCCTCAAGCCGCACTGGCAGTATTGGCATTATCGTTCCTGAACTAGGTGGTCCATTTTATTCGGGCATCTTACATAGC
ATTGAAGAGCGCTTACGCCGCATGGGTTACCACGTGATAGTGACGGCGGGATCGAATACGGAACAAAGCCAGCGAGAATC
GGTAGAGTTTCTGCTTGGTCGCCGTGTTGATGCGATGATTCTGCACACACAAAGCCTTTCTGATGATTATCTGATCGACC
TCGATAACAAAGGGATTCCAGTAGTGCTGGTTAACCGATACATCCCTGAAATGGCTCATAGCTGTATCGAGATCGATAAC
GAATTTGGTGGCCGAATGGCGACTGAATACTTGTTGCGAATGGGGCATCGTAACATTGCATGTATTACCGGACCTCTGGA
CAGATCTGACGCACGGGGGCGTCTACAAGGTTACCGCAAGGCTCTTGAAGAAGCGGAAATTGCGTATGACGAAGCGTTAG
TGTCCGAGGCCGGTTTTACAGAAGAATCTGGTATCAGTGCGATGCGCAAATTGCTTAAGCGTGAAAGCGGTTTCACTGCA
GTGTTTGCTTGTAATGATCACATGGCGTTTGGTGCTTATGAAGTCTTGAAAGCAGAAGGTATGCAGGTGCCAGAGCAAAT
CTCTCTCGTAGGATTTGATGACATCTTGTTTGCTCGCTATCTCACGCCAGCCCTTACCACGGTTAACTTCCCGATAGAAC
AGATGAGCGCAGAGGCGGTACAACTTGTCATCCAAGCGCTGAACAAGAACAAACGTGATGTGAACTTCAAACTCACTCCT
ACCCTAGTGCCAAGAAGTTCGGTCAAGGAACTCAATACTCTCTAG

Upstream 100 bases:

>100_bases
ATACTCACGCTAACCATCTACTGGATATTGAATAATGCGTCCATGAAAGCGGTTTCGGAGTGTTTGAAACTTGCGATGTG
GAGTCATTAAAGAGGTTGAT

Downstream 100 bases:

>100_bases
AACAATAATTAAGGACAACAACATGAAACTCAAAACTTTGACGCTTGCCATGACGGCTGCACTTGGTGTTGCTGCAACGG
TAAACGCTGCCGATGAAACT

Product: hypothetical protein

Products: NA

Alternate protein names: Galactose operon repressor [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MATIKDVSEYAGVSQATVSRVINGTCRVSHDKKLKVEKAIKELGYRPNSIAQALASSRTGSIGIIVPELGGPFYSGILHS
IEERLRRMGYHVIVTAGSNTEQSQRESVEFLLGRRVDAMILHTQSLSDDYLIDLDNKGIPVVLVNRYIPEMAHSCIEIDN
EFGGRMATEYLLRMGHRNIACITGPLDRSDARGRLQGYRKALEEAEIAYDEALVSEAGFTEESGISAMRKLLKRESGFTA
VFACNDHMAFGAYEVLKAEGMQVPEQISLVGFDDILFARYLTPALTTVNFPIEQMSAEAVQLVIQALNKNKRDVNFKLTP
TLVPRSSVKELNTL

Sequences:

>Translated_334_residues
MATIKDVSEYAGVSQATVSRVINGTCRVSHDKKLKVEKAIKELGYRPNSIAQALASSRTGSIGIIVPELGGPFYSGILHS
IEERLRRMGYHVIVTAGSNTEQSQRESVEFLLGRRVDAMILHTQSLSDDYLIDLDNKGIPVVLVNRYIPEMAHSCIEIDN
EFGGRMATEYLLRMGHRNIACITGPLDRSDARGRLQGYRKALEEAEIAYDEALVSEAGFTEESGISAMRKLLKRESGFTA
VFACNDHMAFGAYEVLKAEGMQVPEQISLVGFDDILFARYLTPALTTVNFPIEQMSAEAVQLVIQALNKNKRDVNFKLTP
TLVPRSSVKELNTL
>Mature_333_residues
ATIKDVSEYAGVSQATVSRVINGTCRVSHDKKLKVEKAIKELGYRPNSIAQALASSRTGSIGIIVPELGGPFYSGILHSI
EERLRRMGYHVIVTAGSNTEQSQRESVEFLLGRRVDAMILHTQSLSDDYLIDLDNKGIPVVLVNRYIPEMAHSCIEIDNE
FGGRMATEYLLRMGHRNIACITGPLDRSDARGRLQGYRKALEEAEIAYDEALVSEAGFTEESGISAMRKLLKRESGFTAV
FACNDHMAFGAYEVLKAEGMQVPEQISLVGFDDILFARYLTPALTTVNFPIEQMSAEAVQLVIQALNKNKRDVNFKLTPT
LVPRSSVKELNTL

Specific function: Repressor of the galactose operon. Binds galactose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=330, Percent_Identity=39.3939393939394, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=40.0602409638554, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=36.969696969697, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=35.7357357357357, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789068, Length=311, Percent_Identity=34.4051446945338, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1790369, Length=307, Percent_Identity=34.2019543973941, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=30.0319488817891, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786540, Length=340, Percent_Identity=31.1764705882353, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=26.2996941896024, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787906, Length=329, Percent_Identity=29.1793313069909, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790715, Length=313, Percent_Identity=25.2396166134185, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789456, Length=315, Percent_Identity=24.7619047619048, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786268, Length=316, Percent_Identity=23.1012658227848, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790192, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=24.0506329113924, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36947; Mature: 36816

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKDVSEYAGVSQATVSRVINGTCRVSHDKKLKVEKAIKELGYRPNSIAQALASSRTG
CCCHHHHHHHCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
SIGIIVPELGGPFYSGILHSIEERLRRMGYHVIVTAGSNTEQSQRESVEFLLGRRVDAMI
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LHTQSLSDDYLIDLDNKGIPVVLVNRYIPEMAHSCIEIDNEFGGRMATEYLLRMGHRNIA
EEECCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEE
CITGPLDRSDARGRLQGYRKALEEAEIAYDEALVSEAGFTEESGISAMRKLLKRESGFTA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEE
VFACNDHMAFGAYEVLKAEGMQVPEQISLVGFDDILFARYLTPALTTVNFPIEQMSAEAV
EEEECCCCHHHHHHHHHHCCCCCCHHHEECCHHHHHHHHHHHHHHHEECCCHHHHHHHHH
QLVIQALNKNKRDVNFKLTPTLVPRSSVKELNTL
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCC
>Mature Secondary Structure 
ATIKDVSEYAGVSQATVSRVINGTCRVSHDKKLKVEKAIKELGYRPNSIAQALASSRTG
CCHHHHHHHCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
SIGIIVPELGGPFYSGILHSIEERLRRMGYHVIVTAGSNTEQSQRESVEFLLGRRVDAMI
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LHTQSLSDDYLIDLDNKGIPVVLVNRYIPEMAHSCIEIDNEFGGRMATEYLLRMGHRNIA
EEECCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEE
CITGPLDRSDARGRLQGYRKALEEAEIAYDEALVSEAGFTEESGISAMRKLLKRESGFTA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEE
VFACNDHMAFGAYEVLKAEGMQVPEQISLVGFDDILFARYLTPALTTVNFPIEQMSAEAV
EEEECCCCHHHHHHHHHHCCCCCCHHHEECCHHHHHHHHHHHHHHHEECCCHHHHHHHHH
QLVIQALNKNKRDVNFKLTPTLVPRSSVKELNTL
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6283521; 9278503; 6350601; 8188660; 8982002 [H]