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The map label for this gene is yisQ [H]

Identifier: 156978130

GI number: 156978130

Start: 2029745

End: 2031085

Strand: Reverse

Name: yisQ [H]

Synonym: VIBHAR_06935

Alternate gene names: 156978130

Gene position: 2031085-2029745 (Counterclockwise)

Preceding gene: 156978131

Following gene: 156978128

Centisome position: 92.15

GC content: 48.84

Gene sequence:

>1341_bases
ATGCCTAAAAGCCAGAATATCAACCAACGTATGTCCATCGTGGCATTGGCTTGGCCGATACTTGTCGAAATTTTGCTACG
GACGGCTTTAGGAACCAGTGACGTATTCATGTTGAGTGGTTACTCAGACAAAGCCGTGTCTGCGGTTGGGGTAATCACAC
AGTTAACGTTTTTCCTGATCATCGTTTCTACCTTTGTCAGCAGCGGCACGGGTATCTTGATCGCGCAATACAATGGCGCA
GGGCGTGAGAAAGACTCCGTTGATGTCGGTGTTGCCAGTATCGCTTTGTCGGTGATTGTAGGTGCTTTCTTGAGTGTGCT
GGCCGTGATTGGCGCGGTGTTCTTTTTGCCGTATTACGGGCTAGAGGCTCAAGTTGAGCAGTATGCGCGTGAATATTTGC
TTATCAGCGGTGCGATGACATTCAACGTCACCATCGGTATTGTCTTCACCACGATTCTACGTAGCCACGGTTATTCACGC
TCGCCAATGGTCGTTAACCTAATTTCTGGCGTGTTCAACATCATCGGTAACTACATTGCGCTGTATCAGCCGTTTGGTTT
GCCTGTGTATGGCGTTGAAGGTGTTGCAGTGGCGACAGTCGTGAGCCAAGTAATCGGTACATTATTGTTGGGCCTGATTT
TGAAACGCAGCAGCATCGAACTGCCAATGTCTAAGCTTAAACAAGTGCCGAAAGATGTGTTCAAGAAGATCCTAAAAATC
GGTGGCATGAACGCGGGTGAAGTGCTGTCATACAACATGGCGCAAATCTGTATCGTCTACTTTGTGGTGCAAATGGGCAC
CTCTTCGCTCGCGGCATTTACTTATGCACAAAACATCGCGCGTTTCTCTTTCGCGTTTGCGCTAGCGATTGGTCAGGCGG
CTCAAATCCAAACGGGTTACTACATTGGTAAAGGTTGGGTAAGCAGCATTCTGAAACGCGTGCAGATCTACTTCTTGGTC
GGCTTTGCTGCATCAACGGCGGCAACGTGTTTGATTTACCTGTTCCACGAAGAGATTTTGAGCGTGTTTACCGATCAGCC
AGAAATCTTGGCATTGGCAGGTGCCTTAGTGATGGGGTCTATCGTGTTAGAAGCTGGCCGCGTGTTTAACTTGATCTTCA
TCTCGGCACTGAAAGGCGCTGGTGATATCAAGTTCCCAGTACAGATGGGGATTCTCAGCATGTGGGGCCTGGGTGTGGTG
TTCTCTTACATCTTGGTTATTCACTTGGGCTACGGCGTGATTGGTGCGTGGATGGCGATTGCTTTGGATGAATGGGTACG
CGGCATCATCATGGCAAGACGTTGGCGCTCTCAAGTATGGACGAAGTTTAAAGTAAGCTAA

Upstream 100 bases:

>100_bases
ACAATTATCAAAATAGCCAAATTCTAAGGAATCTAATTTTTTGAACTGCCTCACAGTTATCTGTGGGGCAGTTTTTAGTT
GTAGGAAAGGTCCCAAACAC

Downstream 100 bases:

>100_bases
CTTCTGTTCACAAAAAACCGAGATTCCAGACATCTCGTTCCTCGATTCTGGAATGACAATGTTTAGTTATGGTGATTTGA
AACCTTGTTCTATAAAGCGT

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MPKSQNINQRMSIVALAWPILVEILLRTALGTSDVFMLSGYSDKAVSAVGVITQLTFFLIIVSTFVSSGTGILIAQYNGA
GREKDSVDVGVASIALSVIVGAFLSVLAVIGAVFFLPYYGLEAQVEQYAREYLLISGAMTFNVTIGIVFTTILRSHGYSR
SPMVVNLISGVFNIIGNYIALYQPFGLPVYGVEGVAVATVVSQVIGTLLLGLILKRSSIELPMSKLKQVPKDVFKKILKI
GGMNAGEVLSYNMAQICIVYFVVQMGTSSLAAFTYAQNIARFSFAFALAIGQAAQIQTGYYIGKGWVSSILKRVQIYFLV
GFAASTAATCLIYLFHEEILSVFTDQPEILALAGALVMGSIVLEAGRVFNLIFISALKGAGDIKFPVQMGILSMWGLGVV
FSYILVIHLGYGVIGAWMAIALDEWVRGIIMARRWRSQVWTKFKVS

Sequences:

>Translated_446_residues
MPKSQNINQRMSIVALAWPILVEILLRTALGTSDVFMLSGYSDKAVSAVGVITQLTFFLIIVSTFVSSGTGILIAQYNGA
GREKDSVDVGVASIALSVIVGAFLSVLAVIGAVFFLPYYGLEAQVEQYAREYLLISGAMTFNVTIGIVFTTILRSHGYSR
SPMVVNLISGVFNIIGNYIALYQPFGLPVYGVEGVAVATVVSQVIGTLLLGLILKRSSIELPMSKLKQVPKDVFKKILKI
GGMNAGEVLSYNMAQICIVYFVVQMGTSSLAAFTYAQNIARFSFAFALAIGQAAQIQTGYYIGKGWVSSILKRVQIYFLV
GFAASTAATCLIYLFHEEILSVFTDQPEILALAGALVMGSIVLEAGRVFNLIFISALKGAGDIKFPVQMGILSMWGLGVV
FSYILVIHLGYGVIGAWMAIALDEWVRGIIMARRWRSQVWTKFKVS
>Mature_445_residues
PKSQNINQRMSIVALAWPILVEILLRTALGTSDVFMLSGYSDKAVSAVGVITQLTFFLIIVSTFVSSGTGILIAQYNGAG
REKDSVDVGVASIALSVIVGAFLSVLAVIGAVFFLPYYGLEAQVEQYAREYLLISGAMTFNVTIGIVFTTILRSHGYSRS
PMVVNLISGVFNIIGNYIALYQPFGLPVYGVEGVAVATVVSQVIGTLLLGLILKRSSIELPMSKLKQVPKDVFKKILKIG
GMNAGEVLSYNMAQICIVYFVVQMGTSSLAAFTYAQNIARFSFAFALAIGQAAQIQTGYYIGKGWVSSILKRVQIYFLVG
FAASTAATCLIYLFHEEILSVFTDQPEILALAGALVMGSIVLEAGRVFNLIFISALKGAGDIKFPVQMGILSMWGLGVVF
SYILVIHLGYGVIGAWMAIALDEWVRGIIMARRWRSQVWTKFKVS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=459, Percent_Identity=25.7080610021786, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994890, Length=419, Percent_Identity=24.3436754176611, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48303; Mature: 48172

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSQNINQRMSIVALAWPILVEILLRTALGTSDVFMLSGYSDKAVSAVGVITQLTFFLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
IVSTFVSSGTGILIAQYNGAGREKDSVDVGVASIALSVIVGAFLSVLAVIGAVFFLPYYG
HHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEAQVEQYAREYLLISGAMTFNVTIGIVFTTILRSHGYSRSPMVVNLISGVFNIIGNYIA
CHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LYQPFGLPVYGVEGVAVATVVSQVIGTLLLGLILKRSSIELPMSKLKQVPKDVFKKILKI
HHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GGMNAGEVLSYNMAQICIVYFVVQMGTSSLAAFTYAQNIARFSFAFALAIGQAAQIQTGY
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCE
YIGKGWVSSILKRVQIYFLVGFAASTAATCLIYLFHEEILSVFTDQPEILALAGALVMGS
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IVLEAGRVFNLIFISALKGAGDIKFPVQMGILSMWGLGVVFSYILVIHLGYGVIGAWMAI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDEWVRGIIMARRWRSQVWTKFKVS
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKSQNINQRMSIVALAWPILVEILLRTALGTSDVFMLSGYSDKAVSAVGVITQLTFFLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
IVSTFVSSGTGILIAQYNGAGREKDSVDVGVASIALSVIVGAFLSVLAVIGAVFFLPYYG
HHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEAQVEQYAREYLLISGAMTFNVTIGIVFTTILRSHGYSRSPMVVNLISGVFNIIGNYIA
CHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LYQPFGLPVYGVEGVAVATVVSQVIGTLLLGLILKRSSIELPMSKLKQVPKDVFKKILKI
HHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GGMNAGEVLSYNMAQICIVYFVVQMGTSSLAAFTYAQNIARFSFAFALAIGQAAQIQTGY
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCE
YIGKGWVSSILKRVQIYFLVGFAASTAATCLIYLFHEEILSVFTDQPEILALAGALVMGS
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IVLEAGRVFNLIFISALKGAGDIKFPVQMGILSMWGLGVVFSYILVIHLGYGVIGAWMAI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDEWVRGIIMARRWRSQVWTKFKVS
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]