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The map label for this gene is supH [H]

Identifier: 156978128

GI number: 156978128

Start: 2026457

End: 2027254

Strand: Reverse

Name: supH [H]

Synonym: VIBHAR_06933

Alternate gene names: 156978128

Gene position: 2027254-2026457 (Counterclockwise)

Preceding gene: 156978130

Following gene: 156978123

Centisome position: 91.98

GC content: 46.49

Gene sequence:

>798_bases
ATGTCACAAGCTAGCATCAAATTTATTGCCACCGATATGGATGGCACCTTGCTTGACCAATATGGTCGTTTAGACCCTGA
GTTCTTTGATCTGTTTTTGCAGCTAGAAGAGAAGGGCATTTTGTTTTCGGCAGCATCGGGTCGTCAGTATTACAGTTTGC
GCGATACGTTTGCACCGATTCAAGATCGTATGATTTATGTGGCGGAAAACGGCACCTTGGTGATGTATCAGGACAAAGAG
TTATACAGCTGCACCATTCCAAAGTCGGAAATTGATGCGATCATTCAAGCGGCTCGCGAAATTGAAGGTACGCACCTAGT
GCTGAGTGGAAAGCGCTCTGCATACATCGAAACTCAAGACCCGAAAGCGTTGGAGGAGTTCCAGAAATACTACCACCGTT
GTGAATACGTGCCAGATTTATTGGCCGTAGATGATGAATTCATCAAGGTCGCGATTTGTCATTTTGGTGGCTCGGAAGAG
TTAGTGTACCCAACCATGAAAGCGAAGTTCGATGACACGCATCAAGTGGTGGTGAGTGCGAAGATTTGGCTGGATGTCAT
GAATGCTGAAGCATCAAAAGGTGCGGCCATCAAACATCTTCAAGAAACCATGGGTTTTGGTCCTGAAGAGACCATGACGT
TCGCTGATTACCTGAATGACCTAGAGATGCTGCAAGTGAGCAAGCATTCCTACGCGATGGAAAACGCGCACGAAGCGGTG
AAGAAAATCGCACGCTTCTCAGCACCAAGCAATCGTGACTCTGGCGTAATGAAAGTGATCAAAGAGAAAGTGCTGTAA

Upstream 100 bases:

>100_bases
GCTTGAGATTCACCCAATATCCTGTACCTTAGCGTGATTGTTTTTTGCAGCCGTTTTCATTCGCAGAGTGACCTGTGCTG
CTTATTTTTGAGTTGAAGTC

Downstream 100 bases:

>100_bases
TTTCTGCCTCGCCAATTTCGAACATAAAAAAGCCCCGCTGCTTAGTGAGCGGGGCTTTTGTTTATCTGAAGTTCAGTATC
TGAAGCTAAGTATGCGTCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSQASIKFIATDMDGTLLDQYGRLDPEFFDLFLQLEEKGILFSAASGRQYYSLRDTFAPIQDRMIYVAENGTLVMYQDKE
LYSCTIPKSEIDAIIQAAREIEGTHLVLSGKRSAYIETQDPKALEEFQKYYHRCEYVPDLLAVDDEFIKVAICHFGGSEE
LVYPTMKAKFDDTHQVVVSAKIWLDVMNAEASKGAAIKHLQETMGFGPEETMTFADYLNDLEMLQVSKHSYAMENAHEAV
KKIARFSAPSNRDSGVMKVIKEKVL

Sequences:

>Translated_265_residues
MSQASIKFIATDMDGTLLDQYGRLDPEFFDLFLQLEEKGILFSAASGRQYYSLRDTFAPIQDRMIYVAENGTLVMYQDKE
LYSCTIPKSEIDAIIQAAREIEGTHLVLSGKRSAYIETQDPKALEEFQKYYHRCEYVPDLLAVDDEFIKVAICHFGGSEE
LVYPTMKAKFDDTHQVVVSAKIWLDVMNAEASKGAAIKHLQETMGFGPEETMTFADYLNDLEMLQVSKHSYAMENAHEAV
KKIARFSAPSNRDSGVMKVIKEKVL
>Mature_264_residues
SQASIKFIATDMDGTLLDQYGRLDPEFFDLFLQLEEKGILFSAASGRQYYSLRDTFAPIQDRMIYVAENGTLVMYQDKEL
YSCTIPKSEIDAIIQAAREIEGTHLVLSGKRSAYIETQDPKALEEFQKYYHRCEYVPDLLAVDDEFIKVAICHFGGSEEL
VYPTMKAKFDDTHQVVVSAKIWLDVMNAEASKGAAIKHLQETMGFGPEETMTFADYLNDLEMLQVSKHSYAMENAHEAVK
KIARFSAPSNRDSGVMKVIKEKVL

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=259, Percent_Identity=31.6602316602317, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87081790, Length=266, Percent_Identity=33.8345864661654, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367265, Length=272, Percent_Identity=23.8970588235294, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30046; Mature: 29914

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQASIKFIATDMDGTLLDQYGRLDPEFFDLFLQLEEKGILFSAASGRQYYSLRDTFAPI
CCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHCCC
QDRMIYVAENGTLVMYQDKELYSCTIPKSEIDAIIQAAREIEGTHLVLSGKRSAYIETQD
CCCEEEEEECCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCC
PKALEEFQKYYHRCEYVPDLLAVDDEFIKVAICHFGGSEELVYPTMKAKFDDTHQVVVSA
CHHHHHHHHHHHHHHCCCHHHHCCCHHEEEEEEECCCCCCEEECHHHCCCCCCHHEEEEH
KIWLDVMNAEASKGAAIKHLQETMGFGPEETMTFADYLNDLEMLQVSKHSYAMENAHEAV
HHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KKIARFSAPSNRDSGVMKVIKEKVL
HHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SQASIKFIATDMDGTLLDQYGRLDPEFFDLFLQLEEKGILFSAASGRQYYSLRDTFAPI
CCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHCCC
QDRMIYVAENGTLVMYQDKELYSCTIPKSEIDAIIQAAREIEGTHLVLSGKRSAYIETQD
CCCEEEEEECCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCC
PKALEEFQKYYHRCEYVPDLLAVDDEFIKVAICHFGGSEELVYPTMKAKFDDTHQVVVSA
CHHHHHHHHHHHHHHCCCHHHHCCCHHEEEEEEECCCCCCEEECHHHCCCCCCHHEEEEH
KIWLDVMNAEASKGAAIKHLQETMGFGPEETMTFADYLNDLEMLQVSKHSYAMENAHEAV
HHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KKIARFSAPSNRDSGVMKVIKEKVL
HHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]