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The map label for this gene is yjjG [H]

Identifier: 156977890

GI number: 156977890

Start: 1818775

End: 1819449

Strand: Reverse

Name: yjjG [H]

Synonym: VIBHAR_06682

Alternate gene names: 156977890

Gene position: 1819449-1818775 (Counterclockwise)

Preceding gene: 156977892

Following gene: 156977887

Centisome position: 82.55

GC content: 46.81

Gene sequence:

>675_bases
ATGAAATACGATTGGATCTTGTTTGACGCTGACGAAACCTTGTTTCACTTTGACGCCTTCAAAGGTTTACAGCTGATGTT
TTCTCGCAAAGGCGTAGATTTTACCGAGCAAGATTTTGCCCATTACCAAACGGTGAACAAGCCACTTTGGGTGGATTACC
AAGATGGTAAAGTGACAGCAGATGAGCTGAAGCATAAACGCTTTACGGAGTGGGCAGAAAAGCTCAACACCACAACGGCG
GATCTCAACAGTGCATTCCTAGAAGCGATGGCAGACATCTGCACGTTGCTACCGGGTGCGAAAGAACTGATGGAAGCGCT
AAAAGGTAAAGCCAAAATGGGCATCATCACCAATGGTTTTACCGAGCTTCAAGCGATTCGCCTAGAGCGCACAGGTATGA
GCGATTACTTCGAGCATGTGGTAATTTCTGAGCAAGTTGGTATTGCCAAGCCGGATTTAGGCATCTTTGAGTACGCGATG
ACGCAAATGGGTAACCCATGTAAGACTCGTGTCCTGATGGTGGGTGACAACCTGCATTCTGATATCTTAGGTGGCAATAA
CTTTGGCATTGAAACGTGTTGGCTGAACACCACAGGTGCAAGTATAGATGAGCGTATTGCACCAAGCTACACGGTGGAAT
CGTTGAACGAGCTTAAGAGCATCCTCGTCGCTTAA

Upstream 100 bases:

>100_bases
GCAAAACGCTACAATCATTTTCCAATTATAGAGATTATCTAAAAGAAGAAAACAATTAGACTATGCGGCAGAAAACGACC
TGGATATTGGAAAGAAGAAA

Downstream 100 bases:

>100_bases
GCTTATGTGAACAAACAAACGAAAAAAGCGCTGATTTCTCAGCGCTTTTTTGTTTCTATCGATGCTGTTTTGTATTCATC
GAGCTTGTTTATTAGCTAGC

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKYDWILFDADETLFHFDAFKGLQLMFSRKGVDFTEQDFAHYQTVNKPLWVDYQDGKVTADELKHKRFTEWAEKLNTTTA
DLNSAFLEAMADICTLLPGAKELMEALKGKAKMGIITNGFTELQAIRLERTGMSDYFEHVVISEQVGIAKPDLGIFEYAM
TQMGNPCKTRVLMVGDNLHSDILGGNNFGIETCWLNTTGASIDERIAPSYTVESLNELKSILVA

Sequences:

>Translated_224_residues
MKYDWILFDADETLFHFDAFKGLQLMFSRKGVDFTEQDFAHYQTVNKPLWVDYQDGKVTADELKHKRFTEWAEKLNTTTA
DLNSAFLEAMADICTLLPGAKELMEALKGKAKMGIITNGFTELQAIRLERTGMSDYFEHVVISEQVGIAKPDLGIFEYAM
TQMGNPCKTRVLMVGDNLHSDILGGNNFGIETCWLNTTGASIDERIAPSYTVESLNELKSILVA
>Mature_224_residues
MKYDWILFDADETLFHFDAFKGLQLMFSRKGVDFTEQDFAHYQTVNKPLWVDYQDGKVTADELKHKRFTEWAEKLNTTTA
DLNSAFLEAMADICTLLPGAKELMEALKGKAKMGIITNGFTELQAIRLERTGMSDYFEHVVISEQVGIAKPDLGIFEYAM
TQMGNPCKTRVLMVGDNLHSDILGGNNFGIETCWLNTTGASIDERIAPSYTVESLNELKSILVA

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1790833, Length=222, Percent_Identity=60.3603603603604, Blast_Score=286, Evalue=7e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25211; Mature: 25211

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYDWILFDADETLFHFDAFKGLQLMFSRKGVDFTEQDFAHYQTVNKPLWVDYQDGKVTA
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCEECH
DELKHKRFTEWAEKLNTTTADLNSAFLEAMADICTLLPGAKELMEALKGKAKMGIITNGF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCH
TELQAIRLERTGMSDYFEHVVISEQVGIAKPDLGIFEYAMTQMGNPCKTRVLMVGDNLHS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHH
DILGGNNFGIETCWLNTTGASIDERIAPSYTVESLNELKSILVA
HHCCCCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYDWILFDADETLFHFDAFKGLQLMFSRKGVDFTEQDFAHYQTVNKPLWVDYQDGKVTA
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCEECH
DELKHKRFTEWAEKLNTTTADLNSAFLEAMADICTLLPGAKELMEALKGKAKMGIITNGF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCH
TELQAIRLERTGMSDYFEHVVISEQVGIAKPDLGIFEYAMTQMGNPCKTRVLMVGDNLHS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHH
DILGGNNFGIETCWLNTTGASIDERIAPSYTVESLNELKSILVA
HHCCCCCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]