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The map label for this gene is citR [H]

Identifier: 156977723

GI number: 156977723

Start: 1665096

End: 1665965

Strand: Reverse

Name: citR [H]

Synonym: VIBHAR_06511

Alternate gene names: 156977723

Gene position: 1665965-1665096 (Counterclockwise)

Preceding gene: 156977725

Following gene: 156977722

Centisome position: 75.59

GC content: 46.44

Gene sequence:

>870_bases
ATGTTAGATTTGAACTGGTTACGCACCTTTGTCACTTTGGCAGAAGTAAAACATTTCGGAAAAACAGCAATTGAACTGCA
CATGACGCAGCCAAATGTCAGTCTTCATATCAAACAGCTAGAGCAAGCAACGCGGGCTAAGTTGATTGAACGTAACCCTG
TGCAATTGACCCAAGCCGGAAAGCGTTTGTTAGACACCGCACAGCACATGCTGAATGAGCTGCAAATCTGCCAATCCGAT
CTCAATGCCATTAATGACTTAACGCAAGGAACACTCTCGATTGCGGCGAGTGATATTGTCTCGCGCCTGTTACTTATCAG
GCCATTCCAACAATTCAAAAACGAATATCCTGGTATCGACTTAGCGCTGTTCAACACCACTTCATCACAAGCGGTAGATT
TAGTAAAAAGTGCCCGCGCAGACATCGGCTTTGTTATTGCGCAGAAAGAGAGTCAACCGCTGCACTTTACTCCTCTGACG
CAAATACACTGGTGTGCTTTCGGCGATAATATTTTTAAATGGAAAGAGAACACGGAAGAAAACCAAACCTTGATTCTACT
GGGGCACGACACCCGAACGCGTGAACTGATTGATGCCTCTCTGCCAGAGCTAAACCTGCCAAAACACAGAGTTATGGAAG
TGGGTAGTGTCGAGGCTCAAATTGATTGGGCAGAAGCCGGATTCGGAACCGCAATTGTACCGGACTTCTCACTCGATCCA
AGATTAAAACTCTCACGAGAAGTGACGCCCTTACCCAGCTTCCCCAACACTGATTTTGGCTACATCGTGCGCCAGAATCA
GGTGCTATCCAAAGCTGCCAAACAGTTATTGAAGTGGGTGGGTGAGAATGTATCTGTGGTGGAGGTTTAA

Upstream 100 bases:

>100_bases
TTCTCCAAAAACAGACCGGAAAATCTTAGGATGCTCGCATGAATAAGAGAAATTAATTATACTCATTAACTTGATAAGAA
AATCATATCGGGTAATTTCT

Downstream 100 bases:

>100_bases
CGTTATGCAAGACACAACGATTACCATCCCTTTACCATCTTTGATTCACCGAATTGGTGGTGACCATGCTAAGCGAGCCA
AAGCTATAGCCGCAGAGAAC

Product: transcriptional regulator

Products: NA

Alternate protein names: Citrate synthase I repressor [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLDLNWLRTFVTLAEVKHFGKTAIELHMTQPNVSLHIKQLEQATRAKLIERNPVQLTQAGKRLLDTAQHMLNELQICQSD
LNAINDLTQGTLSIAASDIVSRLLLIRPFQQFKNEYPGIDLALFNTTSSQAVDLVKSARADIGFVIAQKESQPLHFTPLT
QIHWCAFGDNIFKWKENTEENQTLILLGHDTRTRELIDASLPELNLPKHRVMEVGSVEAQIDWAEAGFGTAIVPDFSLDP
RLKLSREVTPLPSFPNTDFGYIVRQNQVLSKAAKQLLKWVGENVSVVEV

Sequences:

>Translated_289_residues
MLDLNWLRTFVTLAEVKHFGKTAIELHMTQPNVSLHIKQLEQATRAKLIERNPVQLTQAGKRLLDTAQHMLNELQICQSD
LNAINDLTQGTLSIAASDIVSRLLLIRPFQQFKNEYPGIDLALFNTTSSQAVDLVKSARADIGFVIAQKESQPLHFTPLT
QIHWCAFGDNIFKWKENTEENQTLILLGHDTRTRELIDASLPELNLPKHRVMEVGSVEAQIDWAEAGFGTAIVPDFSLDP
RLKLSREVTPLPSFPNTDFGYIVRQNQVLSKAAKQLLKWVGENVSVVEV
>Mature_289_residues
MLDLNWLRTFVTLAEVKHFGKTAIELHMTQPNVSLHIKQLEQATRAKLIERNPVQLTQAGKRLLDTAQHMLNELQICQSD
LNAINDLTQGTLSIAASDIVSRLLLIRPFQQFKNEYPGIDLALFNTTSSQAVDLVKSARADIGFVIAQKESQPLHFTPLT
QIHWCAFGDNIFKWKENTEENQTLILLGHDTRTRELIDASLPELNLPKHRVMEVGSVEAQIDWAEAGFGTAIVPDFSLDP
RLKLSREVTPLPSFPNTDFGYIVRQNQVLSKAAKQLLKWVGENVSVVEV

Specific function: Negative regulatory protein for the citA gene for citrate synthase I [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=25.3472222222222, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=224, Percent_Identity=27.6785714285714, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=25.6944444444444, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788626, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI2367136, Length=170, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=30.2158273381295, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=24.3986254295533, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790783, Length=145, Percent_Identity=28.9655172413793, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32541; Mature: 32541

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLNWLRTFVTLAEVKHFGKTAIELHMTQPNVSLHIKQLEQATRAKLIERNPVQLTQAG
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHCCCCHHHHHHH
KRLLDTAQHMLNELQICQSDLNAINDLTQGTLSIAASDIVSRLLLIRPFQQFKNEYPGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LALFNTTSSQAVDLVKSARADIGFVIAQKESQPLHFTPLTQIHWCAFGDNIFKWKENTEE
EEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCEEEEEEECCCEEECCCCCCC
NQTLILLGHDTRTRELIDASLPELNLPKHRVMEVGSVEAQIDWAEAGFGTAIVPDFSLDP
CCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEHHHCCCCCEECCCCCCCC
RLKLSREVTPLPSFPNTDFGYIVRQNQVLSKAAKQLLKWVGENVSVVEV
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MLDLNWLRTFVTLAEVKHFGKTAIELHMTQPNVSLHIKQLEQATRAKLIERNPVQLTQAG
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHCCCCHHHHHHH
KRLLDTAQHMLNELQICQSDLNAINDLTQGTLSIAASDIVSRLLLIRPFQQFKNEYPGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LALFNTTSSQAVDLVKSARADIGFVIAQKESQPLHFTPLTQIHWCAFGDNIFKWKENTEE
EEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCEEEEEEECCCEEECCCCCCC
NQTLILLGHDTRTRELIDASLPELNLPKHRVMEVGSVEAQIDWAEAGFGTAIVPDFSLDP
CCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEHHHCCCCCEECCCCCCCC
RLKLSREVTPLPSFPNTDFGYIVRQNQVLSKAAKQLLKWVGENVSVVEV
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045898; 9579061; 9384377; 8045899 [H]