Click here to switch to the map view.

The map label for this gene is add2 [H]

Identifier: 156977633

GI number: 156977633

Start: 1582723

End: 1583730

Strand: Direct

Name: add2 [H]

Synonym: VIBHAR_06421

Alternate gene names: 156977633

Gene position: 1582723-1583730 (Clockwise)

Preceding gene: 156977632

Following gene: 156977634

Centisome position: 71.81

GC content: 47.52

Gene sequence:

>1008_bases
ATGAACGCATTTATTCAAGGTCTTCCAAAGGTAGAGTTACACTTACATATCGAAGGTTCGCTAGAGCCAGAACTGTTGTT
CGAACTGGCACAACGCAACAACATCGACATTCCTTACGAGTCACCACAGGAACTACGCAAAGCCTACGAGTTCGAAGATT
TACAGTCTTTCCTAGATATCTATTATCAAGGCGCCAACGCGCTGCGTACGGAACAAGATTTCTATGATTTGACGTGGGCA
TACCTAGAGCGCTGCAAAGCCGACAACGTTATCCATACTGAGATCTTCTTTGACCCACAGACCCATACCGATCGCGGCAT
TGAGTTTGAGACGGTCATCAACGGCATTCACCGTGCTATGCAAGATGGTACCGAACAGCTAGGTATTACGTTTCAAATCA
TTGCGTGCTTCTTGCGTCACCTATCGGAAGAGCGCGCGATTGAAACGCTGCAATCAATCATCAAGCATCAAGACAAAATC
ATCGGTGTCGGTTTGGATTCTTCAGAGCTTGGTCACCCACCAGAGAAGTTCAAACGTGCTTTCCAACAAGCCAAAGACGC
TGGCTTACTGACCGTTGCACACGCTGGTGAAGAAGGCCCTGCGCAAAACATTGTCGACTCTGTCGAGATGCTCAGTGTCA
GCCGTGTTGACCATGGTGTTCGCTGCGTTGAGGATGAGTCATTAATGGATGCCCTGATCGAAAGCAAAATGCCACTGACG
GTTTGCCCATTATCGAACATTAAGCTGTGTGTATTTGATGAAATGGAGCAGCACAACATTGTCGATTTGTTGCGTAAAGG
CGTCGCGGTGACGATTAACTCGGACGACCCTGCTTATTTTGGGGGTTACATGACGGATAACTTCATGGCGGTCAGTAATG
CTCACCCAATGACGAAGTCAGAACTCGCTCAGTTCACGATCAATGCGATTAACGCGAGCTTCATTAGCGAGGCACTTAAA
GCCAAATACCGTGCACAAGTCGCTGATTACTTAGCAATCACTGACTGA

Upstream 100 bases:

>100_bases
GGATCTTACTCTTTGTAATAGCGTTCGATTTTTCTCAATCTATACCTATCCTTAAAGTAATTGCATCCACAACAACCATA
AGAAAAAGTGGGAGTTTATT

Downstream 100 bases:

>100_bases
TAAGTAAACTAGTGGTTCTCTAGTCTTTTTGCTATCTATCTGCAACGGTGGATACATGAAGTTGCAGTTAACCGAGCTCA
ACATTAAGAACGCTTTAATA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase 2 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNAFIQGLPKVELHLHIEGSLEPELLFELAQRNNIDIPYESPQELRKAYEFEDLQSFLDIYYQGANALRTEQDFYDLTWA
YLERCKADNVIHTEIFFDPQTHTDRGIEFETVINGIHRAMQDGTEQLGITFQIIACFLRHLSEERAIETLQSIIKHQDKI
IGVGLDSSELGHPPEKFKRAFQQAKDAGLLTVAHAGEEGPAQNIVDSVEMLSVSRVDHGVRCVEDESLMDALIESKMPLT
VCPLSNIKLCVFDEMEQHNIVDLLRKGVAVTINSDDPAYFGGYMTDNFMAVSNAHPMTKSELAQFTINAINASFISEALK
AKYRAQVADYLAITD

Sequences:

>Translated_335_residues
MNAFIQGLPKVELHLHIEGSLEPELLFELAQRNNIDIPYESPQELRKAYEFEDLQSFLDIYYQGANALRTEQDFYDLTWA
YLERCKADNVIHTEIFFDPQTHTDRGIEFETVINGIHRAMQDGTEQLGITFQIIACFLRHLSEERAIETLQSIIKHQDKI
IGVGLDSSELGHPPEKFKRAFQQAKDAGLLTVAHAGEEGPAQNIVDSVEMLSVSRVDHGVRCVEDESLMDALIESKMPLT
VCPLSNIKLCVFDEMEQHNIVDLLRKGVAVTINSDDPAYFGGYMTDNFMAVSNAHPMTKSELAQFTINAINASFISEALK
AKYRAQVADYLAITD
>Mature_335_residues
MNAFIQGLPKVELHLHIEGSLEPELLFELAQRNNIDIPYESPQELRKAYEFEDLQSFLDIYYQGANALRTEQDFYDLTWA
YLERCKADNVIHTEIFFDPQTHTDRGIEFETVINGIHRAMQDGTEQLGITFQIIACFLRHLSEERAIETLQSIIKHQDKI
IGVGLDSSELGHPPEKFKRAFQQAKDAGLLTVAHAGEEGPAQNIVDSVEMLSVSRVDHGVRCVEDESLMDALIESKMPLT
VCPLSNIKLCVFDEMEQHNIVDLLRKGVAVTINSDDPAYFGGYMTDNFMAVSNAHPMTKSELAQFTINAINASFISEALK
AKYRAQVADYLAITD

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=337, Percent_Identity=22.8486646884273, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1787910, Length=326, Percent_Identity=26.3803680981595, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI32565969, Length=339, Percent_Identity=24.7787610619469, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538512, Length=339, Percent_Identity=24.7787610619469, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324188, Length=334, Percent_Identity=43.1137724550898, Blast_Score=273, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24645260, Length=345, Percent_Identity=23.768115942029, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37772; Mature: 37772

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFIQGLPKVELHLHIEGSLEPELLFELAQRNNIDIPYESPQELRKAYEFEDLQSFLDI
CCCHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHH
YYQGANALRTEQDFYDLTWAYLERCKADNVIHTEIFFDPQTHTDRGIEFETVINGIHRAM
HHCCCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QDGTEQLGITFQIIACFLRHLSEERAIETLQSIIKHQDKIIGVGLDSSELGHPPEKFKRA
HCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCHHHHHHH
FQQAKDAGLLTVAHAGEEGPAQNIVDSVEMLSVSRVDHGVRCVEDESLMDALIESKMPLT
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCEE
VCPLSNIKLCVFDEMEQHNIVDLLRKGVAVTINSDDPAYFGGYMTDNFMAVSNAHPMTKS
EECCCCCEEEEECCCHHCHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCHH
ELAQFTINAINASFISEALKAKYRAQVADYLAITD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAFIQGLPKVELHLHIEGSLEPELLFELAQRNNIDIPYESPQELRKAYEFEDLQSFLDI
CCCHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHH
YYQGANALRTEQDFYDLTWAYLERCKADNVIHTEIFFDPQTHTDRGIEFETVINGIHRAM
HHCCCCHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QDGTEQLGITFQIIACFLRHLSEERAIETLQSIIKHQDKIIGVGLDSSELGHPPEKFKRA
HCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCHHHHHHH
FQQAKDAGLLTVAHAGEEGPAQNIVDSVEMLSVSRVDHGVRCVEDESLMDALIESKMPLT
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCEE
VCPLSNIKLCVFDEMEQHNIVDLLRKGVAVTINSDDPAYFGGYMTDNFMAVSNAHPMTKS
EECCCCCEEEEECCCHHCHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEECCCCCCCHH
ELAQFTINAINASFISEALKAKYRAQVADYLAITD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]