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The map label for this gene is eda [H]

Identifier: 156977560

GI number: 156977560

Start: 1516554

End: 1516889

Strand: Reverse

Name: eda [H]

Synonym: VIBHAR_06348

Alternate gene names: 156977560

Gene position: 1516889-1516554 (Counterclockwise)

Preceding gene: 156977561

Following gene: 156977558

Centisome position: 68.82

GC content: 50.6

Gene sequence:

>336_bases
ATGTCCCAAGCAATGATTCAGCAACTTCAGCAATTTAAAGTTATTCCTGTTATCCAAATCAATAAGGTTGAGCACGCGAT
CCCACTGGCGAAAGTGTTAGTAGAAAACGGTCTGCCAGTTGCGGAAGTGACGTTTCGAACAGAAGCCGCTGCCGATGCGA
TTAAAGCCATGCGCGATGCTTACCCGCAAATGTGCATCGGTGCTGGTACGGTACTGACGCCAGAGCAGATTACCCAAGCA
AAAGACGCGGGTGCAGAGTTTATTGTCGCGCCGGGGTTGAACCCTGAGGGATCCCCACATCTTTTCACCGGAACTCTGCC
GCACTTATCGCTTTGA

Upstream 100 bases:

>100_bases
CTCGGTCACGCACTAGCAGCAACCGTTATTCAATATCCTGGCGCGATCATTCCAAATGACGCCATGACTCATCTAATTCG
ATAATTTCCGAGAACGTATT

Downstream 100 bases:

>100_bases
GGCCTCCTACGGCTAAGGCCAGATCCTTCACGCTAAATGAGTAAGCTTCTCTTCCTATCAACTCTTTACCGAGAAAAAAG
TAGGAAAGTACCCGGCGTGT

Product: 2-keto-3-deoxy-6-phosphogluconatealdolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MSQAMIQQLQQFKVIPVIQINKVEHAIPLAKVLVENGLPVAEVTFRTEAAADAIKAMRDAYPQMCIGAGTVLTPEQITQA
KDAGAEFIVAPGLNPEGSPHLFTGTLPHLSL

Sequences:

>Translated_111_residues
MSQAMIQQLQQFKVIPVIQINKVEHAIPLAKVLVENGLPVAEVTFRTEAAADAIKAMRDAYPQMCIGAGTVLTPEQITQA
KDAGAEFIVAPGLNPEGSPHLFTGTLPHLSL
>Mature_110_residues
SQAMIQQLQQFKVIPVIQINKVEHAIPLAKVLVENGLPVAEVTFRTEAAADAIKAMRDAYPQMCIGAGTVLTPEQITQAK
DAGAEFIVAPGLNPEGSPHLFTGTLPHLSL

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=72, Percent_Identity=51.3888888888889, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 11858; Mature: 11727

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAMIQQLQQFKVIPVIQINKVEHAIPLAKVLVENGLPVAEVTFRTEAAADAIKAMRDA
CCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
YPQMCIGAGTVLTPEQITQAKDAGAEFIVAPGLNPEGSPHLFTGTLPHLSL
CHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SQAMIQQLQQFKVIPVIQINKVEHAIPLAKVLVENGLPVAEVTFRTEAAADAIKAMRDA
CHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
YPQMCIGAGTVLTPEQITQAKDAGAEFIVAPGLNPEGSPHLFTGTLPHLSL
CHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]