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The map label for this gene is eda [H]

Identifier: 156977558

GI number: 156977558

Start: 1514920

End: 1515234

Strand: Reverse

Name: eda [H]

Synonym: VIBHAR_06346

Alternate gene names: 156977558

Gene position: 1515234-1514920 (Counterclockwise)

Preceding gene: 156977560

Following gene: 156977557

Centisome position: 68.75

GC content: 50.79

Gene sequence:

>315_bases
ATGCCGATCGTACCGGGTGTGAACAACCCAAGTCAGGTTGAGCAAGCACTAGAGTTGGGTTTGAACTTCCTCAAATTCTT
CCCGGCAGAAGAGAGCGGTGGTATCGCGATGGTGAAGTCACTACTCGCACCTTATGTTGATGTGAGTCTGATGCCGACCG
GCGGTATCGGTAAAAGCAACGTCAATGATTACCTAGCTTTCGACCGTGTGGTTTGCTGCGGTGGTACTTGGATGGTTGCG
CCGAGCTTAATTGAAAACGAACAATGGGACGAAATTGGCAAGCTGGTTCGTGAAGCAGTAGAGCTGGTCGCGTAA

Upstream 100 bases:

>100_bases
CTGCCTACTTTTCACGCTATCTACATGATTCTTCTATGCTAGTTGTGGGGAGCCCTCAGGGTTGAACCCCAATACCGTGC
GTCGTTGCCAAGAAATCAAC

Downstream 100 bases:

>100_bases
CTCAAACAGAGCTCTTTTACCCAAGTCACCAGACCCCATTAAATAGCGTGACTTGGGTTGAACAATTATAGGGTCTGTTG
AACTTTCGAGCTGATTTTTG

Product: 2-keto-3-deoxy-6-phosphogluconatealdolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MPIVPGVNNPSQVEQALELGLNFLKFFPAEESGGIAMVKSLLAPYVDVSLMPTGGIGKSNVNDYLAFDRVVCCGGTWMVA
PSLIENEQWDEIGKLVREAVELVA

Sequences:

>Translated_104_residues
MPIVPGVNNPSQVEQALELGLNFLKFFPAEESGGIAMVKSLLAPYVDVSLMPTGGIGKSNVNDYLAFDRVVCCGGTWMVA
PSLIENEQWDEIGKLVREAVELVA
>Mature_103_residues
PIVPGVNNPSQVEQALELGLNFLKFFPAEESGGIAMVKSLLAPYVDVSLMPTGGIGKSNVNDYLAFDRVVCCGGTWMVAP
SLIENEQWDEIGKLVREAVELVA

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=101, Percent_Identity=41.5841584158416, Blast_Score=97, Evalue=2e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 11196; Mature: 11065

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS00160 ALDOLASE_KDPG_KHG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIVPGVNNPSQVEQALELGLNFLKFFPAEESGGIAMVKSLLAPYVDVSLMPTGGIGKSN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCCC
VNDYLAFDRVVCCGGTWMVAPSLIENEQWDEIGKLVREAVELVA
CHHHHHHHHHHHCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PIVPGVNNPSQVEQALELGLNFLKFFPAEESGGIAMVKSLLAPYVDVSLMPTGGIGKSN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCCC
VNDYLAFDRVVCCGGTWMVAPSLIENEQWDEIGKLVREAVELVA
CHHHHHHHHHHHCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]