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The map label for this gene is aaeR [H]

Identifier: 156977509

GI number: 156977509

Start: 1471918

End: 1472805

Strand: Direct

Name: aaeR [H]

Synonym: VIBHAR_06296

Alternate gene names: 156977509

Gene position: 1471918-1472805 (Clockwise)

Preceding gene: 156977505

Following gene: 156977515

Centisome position: 66.78

GC content: 46.96

Gene sequence:

>888_bases
ATGGACTGGATTCAGAGTGTTAACAGTTACATACGAGTCGTCGAAGAAGGTAGCTTCAACGCCGCGGCGCGAAAGCTCAA
TACCACCAGCTCGGCCATCAGCAAGCGTATCCAATGGTTGGAAGATAAGATTGGTGTTCAGCTTCTCAAGCGAACTACTC
GCTCTATCAGCCAAACGGAAGCTGGTGCACTCTTTTACGAGCGAGCCAAAGTGCAACTCGACTCTTGGCAATCTGTATTG
GACGAAACTCGTTCCGTAAACCAATCTCCAGCGGGGTTACTCAAAATTGGGGCGACATTGGCGGTTGGTTCTAAGTTCTT
AGTACATTACCTCGATGACTTTCTGGAAAAATACCCAGACATCAAACTCCAGCTGATCACGACCCTACCTGGTCAAATTC
CTGAGCTCAGTTTGGATTTGTTCATCAGCAGAGAATTGGAACAACTCAACTCACTGAGCTTTAAAGCCAGCCCATTGTTC
GAGCACAAAGCTCAGTTTTATGCGGCGCCGAGTTACCTAGAGAAACATGGCACACCGCATAGTGTTGAAGAGCTGTCACA
ACATAACGTTTTGATTTGGGGCGAAAAGCCCGTAAGAGAAATCAAGACTAATCATGGGAAACGCATCAGTCTTTCAGGGA
ATTTCGCCACTACAAACCCAGAAGCTCTGTTTCACGGCGCAAAACGGGGCATGGGCATCTTGCTATCAAACAACGTGATG
ATAAAAGAAGACCTGAGATCAGGGGCTTTAGTGCCGATTCTTCCAGACATCACCGCTGATGAAGCTACCGTCTATGCGTA
TTACCCTAAGCTCGATTACCAACACACTCGAACTCAACTCTTCTTGGACTACTTAAAGAGTCGTTTGGAAGAAGAAAAGC
GCGCTTAA

Upstream 100 bases:

>100_bases
TACAACATGACAGTTTTACGACAGACAGTGTATATTTGTTACTCAAAGATGATAATAAGCTTAAATGGAAAGGGATTATT
TCCCCTGAGGATGGAATAAG

Downstream 100 bases:

>100_bases
TCTGATTACGCTTTGGTTGCAAAATTAATGGAAAATCGCAAGAGCGCGTTGGTCTTTCTTGAGTGCTTTTGAGTGATAGA
TAAGAAGTTATCACTTTCCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDWIQSVNSYIRVVEEGSFNAAARKLNTTSSAISKRIQWLEDKIGVQLLKRTTRSISQTEAGALFYERAKVQLDSWQSVL
DETRSVNQSPAGLLKIGATLAVGSKFLVHYLDDFLEKYPDIKLQLITTLPGQIPELSLDLFISRELEQLNSLSFKASPLF
EHKAQFYAAPSYLEKHGTPHSVEELSQHNVLIWGEKPVREIKTNHGKRISLSGNFATTNPEALFHGAKRGMGILLSNNVM
IKEDLRSGALVPILPDITADEATVYAYYPKLDYQHTRTQLFLDYLKSRLEEEKRA

Sequences:

>Translated_295_residues
MDWIQSVNSYIRVVEEGSFNAAARKLNTTSSAISKRIQWLEDKIGVQLLKRTTRSISQTEAGALFYERAKVQLDSWQSVL
DETRSVNQSPAGLLKIGATLAVGSKFLVHYLDDFLEKYPDIKLQLITTLPGQIPELSLDLFISRELEQLNSLSFKASPLF
EHKAQFYAAPSYLEKHGTPHSVEELSQHNVLIWGEKPVREIKTNHGKRISLSGNFATTNPEALFHGAKRGMGILLSNNVM
IKEDLRSGALVPILPDITADEATVYAYYPKLDYQHTRTQLFLDYLKSRLEEEKRA
>Mature_295_residues
MDWIQSVNSYIRVVEEGSFNAAARKLNTTSSAISKRIQWLEDKIGVQLLKRTTRSISQTEAGALFYERAKVQLDSWQSVL
DETRSVNQSPAGLLKIGATLAVGSKFLVHYLDDFLEKYPDIKLQLITTLPGQIPELSLDLFISRELEQLNSLSFKASPLF
EHKAQFYAAPSYLEKHGTPHSVEELSQHNVLIWGEKPVREIKTNHGKRISLSGNFATTNPEALFHGAKRGMGILLSNNVM
IKEDLRSGALVPILPDITADEATVYAYYPKLDYQHTRTQLFLDYLKSRLEEEKRA

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=31.1864406779661, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=27.9310344827586, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786401, Length=282, Percent_Identity=30.8510638297872, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=30.2083333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=28.8590604026846, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=22.742474916388, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI145693105, Length=123, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=283, Percent_Identity=23.6749116607774, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=33.6134453781513, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789173, Length=255, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790011, Length=286, Percent_Identity=24.8251748251748, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=22.8373702422145, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788748, Length=122, Percent_Identity=28.6885245901639, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33351; Mature: 33351

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWIQSVNSYIRVVEEGSFNAAARKLNTTSSAISKRIQWLEDKIGVQLLKRTTRSISQTE
CCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGALFYERAKVQLDSWQSVLDETRSVNQSPAGLLKIGATLAVGSKFLVHYLDDFLEKYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IKLQLITTLPGQIPELSLDLFISRELEQLNSLSFKASPLFEHKAQFYAAPSYLEKHGTPH
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCCCC
SVEELSQHNVLIWGEKPVREIKTNHGKRISLSGNFATTNPEALFHGAKRGMGILLSNNVM
HHHHHHHCCEEEECCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEECCEE
IKEDLRSGALVPILPDITADEATVYAYYPKLDYQHTRTQLFLDYLKSRLEEEKRA
EECHHCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDWIQSVNSYIRVVEEGSFNAAARKLNTTSSAISKRIQWLEDKIGVQLLKRTTRSISQTE
CCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGALFYERAKVQLDSWQSVLDETRSVNQSPAGLLKIGATLAVGSKFLVHYLDDFLEKYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IKLQLITTLPGQIPELSLDLFISRELEQLNSLSFKASPLFEHKAQFYAAPSYLEKHGTPH
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCCCC
SVEELSQHNVLIWGEKPVREIKTNHGKRISLSGNFATTNPEALFHGAKRGMGILLSNNVM
HHHHHHHCCEEEECCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEECCEE
IKEDLRSGALVPILPDITADEATVYAYYPKLDYQHTRTQLFLDYLKSRLEEEKRA
EECHHCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]