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The map label for this gene is ompA [H]

Identifier: 156977475

GI number: 156977475

Start: 1445500

End: 1446504

Strand: Direct

Name: ompA [H]

Synonym: VIBHAR_06262

Alternate gene names: 156977475

Gene position: 1445500-1446504 (Clockwise)

Preceding gene: 156977473

Following gene: 156977476

Centisome position: 65.58

GC content: 44.38

Gene sequence:

>1005_bases
ATGCAATCAATACAAGGAAACACTATGAAAAAAGTAGCAATTGCAGTAGCAGCAGTGGTAGCTGGTGGTTTAATTAACTC
TGCTCAAGCTGAAATGTATATCGGGGGCAAAGTGGGCATGACTACTTTAGATGATGCTTGCTATTTAAACAGCCCTTGTG
ATGATGATGCTTTCGGTGCCGGAATGCACATCGGTTACGATTTTACCGATATCATTGGTCTTGAGTATGGCGTTGATTAC
TTAGGTGACTACAAAGCTAACTTCAAGTCAGGGGCTAATACAGTTGATACGATTGATGGCGACCTTTGGGCACTAACTCT
TGCACCTAAATTTAACTGGCATCTAAACGATACGTGGAACCTATTCGCGAAAATCGGTGGTGCTTACATGATTTCTGGTG
ATGAGAAAGACCTTGTACCAACGGGTTCATTAGGTGCCGAGTACACTATCGACAGAAACTGGAGCGTTCGTGGTGAATAC
CAACGTTACCAAGGTATGTCTGATAATGTGATAGATGACATGGATGCAAACTTCTTCGGTATCGGTGTTAATTACAAATT
CGCGGCAGCGCCAGTTGTAGCTGCAATCGTAACAGAAGAGGTTCTTGAAGAAGAGCCTGTTTTATTAACGAAGACGCACA
AAGAAGAGTACGGTTCAGGCACATTTGAATTCGACAGTGCGAAACTAACTGACTCAGTATCTGAGCGTCTAGACAACTTC
GTTAACTTCTTGAACGAATACCCACAAGCTCAAGTTGAGATTACAGGTTACACGGATAGCTCTGGTCCAGCAGCTTACAA
CCTAAAACTGTCTGAGCGCCGTGCACAAGCTGTTGCAGATTACCTAATCGCAGCAGGTATCGATGCGGACCGTTTCACGG
TTACAGGTATGGGTGAAGAAGATCCAGTTGCTGACAACAGCACTCACGAAGGTCGCGAGCAGAACCGTCGTGTTGTGGTA
CATGTACCTGAGTTCCAATACGAAGAACTTGTACAACCAGAATAA

Upstream 100 bases:

>100_bases
CTAAGATAATGTTGCTTGATGTTAAATTAAATGAATATTAAACTAATTTCTTATAACTACCTAGTTTTACTCTAATTGTT
AAAACAAAGTAGAAATTAAT

Downstream 100 bases:

>100_bases
GATTTTCCACTCTTTTCTCTAGAATAAGGGGTGCTTCGGCATCCCTTTTTGTTTGCTTCGTATTTGTTCACTCCAGCACC
ATTTGCAGCTCAGAATCCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQSIQGNTMKKVAIAVAAVVAGGLINSAQAEMYIGGKVGMTTLDDACYLNSPCDDDAFGAGMHIGYDFTDIIGLEYGVDY
LGDYKANFKSGANTVDTIDGDLWALTLAPKFNWHLNDTWNLFAKIGGAYMISGDEKDLVPTGSLGAEYTIDRNWSVRGEY
QRYQGMSDNVIDDMDANFFGIGVNYKFAAAPVVAAIVTEEVLEEEPVLLTKTHKEEYGSGTFEFDSAKLTDSVSERLDNF
VNFLNEYPQAQVEITGYTDSSGPAAYNLKLSERRAQAVADYLIAAGIDADRFTVTGMGEEDPVADNSTHEGREQNRRVVV
HVPEFQYEELVQPE

Sequences:

>Translated_334_residues
MQSIQGNTMKKVAIAVAAVVAGGLINSAQAEMYIGGKVGMTTLDDACYLNSPCDDDAFGAGMHIGYDFTDIIGLEYGVDY
LGDYKANFKSGANTVDTIDGDLWALTLAPKFNWHLNDTWNLFAKIGGAYMISGDEKDLVPTGSLGAEYTIDRNWSVRGEY
QRYQGMSDNVIDDMDANFFGIGVNYKFAAAPVVAAIVTEEVLEEEPVLLTKTHKEEYGSGTFEFDSAKLTDSVSERLDNF
VNFLNEYPQAQVEITGYTDSSGPAAYNLKLSERRAQAVADYLIAAGIDADRFTVTGMGEEDPVADNSTHEGREQNRRVVV
HVPEFQYEELVQPE
>Mature_334_residues
MQSIQGNTMKKVAIAVAAVVAGGLINSAQAEMYIGGKVGMTTLDDACYLNSPCDDDAFGAGMHIGYDFTDIIGLEYGVDY
LGDYKANFKSGANTVDTIDGDLWALTLAPKFNWHLNDTWNLFAKIGGAYMISGDEKDLVPTGSLGAEYTIDRNWSVRGEY
QRYQGMSDNVIDDMDANFFGIGVNYKFAAAPVVAAIVTEEVLEEEPVLLTKTHKEEYGSGTFEFDSAKLTDSVSERLDNF
VNFLNEYPQAQVEITGYTDSSGPAAYNLKLSERRAQAVADYLIAAGIDADRFTVTGMGEEDPVADNSTHEGREQNRRVVV
HVPEFQYEELVQPE

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=357, Percent_Identity=29.4117647058824, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI48994946, Length=105, Percent_Identity=41.9047619047619, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786962, Length=99, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 36589; Mature: 36589

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIQGNTMKKVAIAVAAVVAGGLINSAQAEMYIGGKVGMTTLDDACYLNSPCDDDAFGA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEECCCEEECCCCCCCCCCC
GMHIGYDFTDIIGLEYGVDYLGDYKANFKSGANTVDTIDGDLWALTLAPKFNWHLNDTWN
CEEECCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEECCHHH
LFAKIGGAYMISGDEKDLVPTGSLGAEYTIDRNWSVRGEYQRYQGMSDNVIDDMDANFFG
HHHHCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEE
IGVNYKFAAAPVVAAIVTEEVLEEEPVLLTKTHKEEYGSGTFEFDSAKLTDSVSERLDNF
EECCCEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCEEECCCHHHHHHHHHHHHH
VNFLNEYPQAQVEITGYTDSSGPAAYNLKLSERRAQAVADYLIAAGIDADRFTVTGMGEE
HHHHHHCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
DPVADNSTHEGREQNRRVVVHVPEFQYEELVQPE
CCCCCCCCCCCHHCCCEEEEECCCCCHHHHCCCC
>Mature Secondary Structure
MQSIQGNTMKKVAIAVAAVVAGGLINSAQAEMYIGGKVGMTTLDDACYLNSPCDDDAFGA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEECCCEEECCCCCCCCCCC
GMHIGYDFTDIIGLEYGVDYLGDYKANFKSGANTVDTIDGDLWALTLAPKFNWHLNDTWN
CEEECCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEECCHHH
LFAKIGGAYMISGDEKDLVPTGSLGAEYTIDRNWSVRGEYQRYQGMSDNVIDDMDANFFG
HHHHCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEE
IGVNYKFAAAPVVAAIVTEEVLEEEPVLLTKTHKEEYGSGTFEFDSAKLTDSVSERLDNF
EECCCEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCEEECCCHHHHHHHHHHHHH
VNFLNEYPQAQVEITGYTDSSGPAAYNLKLSERRAQAVADYLIAAGIDADRFTVTGMGEE
HHHHHHCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
DPVADNSTHEGREQNRRVVVHVPEFQYEELVQPE
CCCCCCCCCCCHHCCCEEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]