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The map label for this gene is moeB [H]

Identifier: 156977450

GI number: 156977450

Start: 1418252

End: 1418962

Strand: Direct

Name: moeB [H]

Synonym: VIBHAR_06237

Alternate gene names: 156977450

Gene position: 1418252-1418962 (Clockwise)

Preceding gene: 156977449

Following gene: 156977458

Centisome position: 64.35

GC content: 46.98

Gene sequence:

>711_bases
GTGGATATTCTTTCCGATCAGGAAATGCTACGTTACAACCGCCAAATCATTCTTCGTCAATTTGACTTTGAAGGGCAAGA
GGCGCTCAAACAAGCGTCAGTATTGATGCTTGGTGCTGGCGGCTTAGGTTGTGCATCAAGCCAATATTTGGCCATCGTCG
AGTTGTCTAACCTTCAGCGCCAAGTACTGCATCACGATGCGGATATTGGCCGTAAGAAGGTAGAGTCGGCGGCAGATGCA
CTACGCGAACTTAACCCGCACATCATTGTAGATACCATCGCAAAGCGTCTTGATGATACAGAGCTAAAAAGCTTGATCGA
ACAGCACACGATTGTTGTTGATGCATCAGATAACGTCGATACGCGTAATCAACTTAACCGCCTATGTTTTGCGACCAAAA
CAGCGCTAATTTCAGGCGCCGCCATTCGCATGGAGGGACAAGTAAGCGTGTTTACTTACGATGACCCAGCGCAACCATGT
TACCAATGCTTGAGTGCCCTTTTTGGCAGTGGCGCATTAAGCTGTGTCGAAGCCGGAGTCATGGCGCCTGTTGTTGGTAT
TGTTGGCGCAGTACAAGCGATGGAAGCGATTAAAGTAATATCTGATTACGGCCAACCAAAGAAAGGCAAAATTCTGATTT
TAGATGCGCTCAGCATGTCTTGGCGAGAAATGAATCTGATGAAAATGCCAACCTGTCCAGTTTGCAACTAA

Upstream 100 bases:

>100_bases
GAACTGTTTTGTTGTGTTAGAGCGCGAGCGCGGCCGTGTGGAAGTAGGTGAAACGGTTCAGATCCAACTATTCAACTCAA
CCCTATACTAGGAAATCGTT

Downstream 100 bases:

>100_bases
CCGGCTTACAACTAACCACCTTATATCAATAAGCCCGCTTTTGCGGGTTTATTTTTGACTTCTGCAAAACAAAAAACCGC
CCGATAAGGGCGGAAAGTCA

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDILSDQEMLRYNRQIILRQFDFEGQEALKQASVLMLGAGGLGCASSQYLAIVELSNLQRQVLHHDADIGRKKVESAADA
LRELNPHIIVDTIAKRLDDTELKSLIEQHTIVVDASDNVDTRNQLNRLCFATKTALISGAAIRMEGQVSVFTYDDPAQPC
YQCLSALFGSGALSCVEAGVMAPVVGIVGAVQAMEAIKVISDYGQPKKGKILILDALSMSWREMNLMKMPTCPVCN

Sequences:

>Translated_236_residues
MDILSDQEMLRYNRQIILRQFDFEGQEALKQASVLMLGAGGLGCASSQYLAIVELSNLQRQVLHHDADIGRKKVESAADA
LRELNPHIIVDTIAKRLDDTELKSLIEQHTIVVDASDNVDTRNQLNRLCFATKTALISGAAIRMEGQVSVFTYDDPAQPC
YQCLSALFGSGALSCVEAGVMAPVVGIVGAVQAMEAIKVISDYGQPKKGKILILDALSMSWREMNLMKMPTCPVCN
>Mature_236_residues
MDILSDQEMLRYNRQIILRQFDFEGQEALKQASVLMLGAGGLGCASSQYLAIVELSNLQRQVLHHDADIGRKKVESAADA
LRELNPHIIVDTIAKRLDDTELKSLIEQHTIVVDASDNVDTRNQLNRLCFATKTALISGAAIRMEGQVSVFTYDDPAQPC
YQCLSALFGSGALSCVEAGVMAPVVGIVGAVQAMEAIKVISDYGQPKKGKILILDALSMSWREMNLMKMPTCPVCN

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=229, Percent_Identity=37.9912663755458, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI23510338, Length=166, Percent_Identity=29.5180722891566, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI23510340, Length=166, Percent_Identity=29.5180722891566, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787048, Length=245, Percent_Identity=60.4081632653061, Blast_Score=309, Evalue=1e-85,
Organism=Escherichia coli, GI87082356, Length=245, Percent_Identity=37.1428571428571, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=33.8709677419355, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193203301, Length=158, Percent_Identity=29.1139240506329, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=213, Percent_Identity=34.2723004694836, Blast_Score=125, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322639, Length=164, Percent_Identity=27.4390243902439, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582879, Length=249, Percent_Identity=38.1526104417671, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24660640, Length=152, Percent_Identity=28.2894736842105, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 25786; Mature: 25786

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILSDQEMLRYNRQIILRQFDFEGQEALKQASVLMLGAGGLGCASSQYLAIVELSNLQR
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCCCCCCEEEEEEHHHHHH
QVLHHDADIGRKKVESAADALRELNPHIIVDTIAKRLDDTELKSLIEQHTIVVDASDNVD
HHHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCHHHHHHHHHHCEEEEECCCCCC
TRNQLNRLCFATKTALISGAAIRMEGQVSVFTYDDPAQPCYQCLSALFGSGALSCVEAGV
HHHHHHHHHHHHHHHHHCCCEEEEECEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
MAPVVGIVGAVQAMEAIKVISDYGQPKKGKILILDALSMSWREMNLMKMPTCPVCN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCEECCCCCCCC
>Mature Secondary Structure
MDILSDQEMLRYNRQIILRQFDFEGQEALKQASVLMLGAGGLGCASSQYLAIVELSNLQR
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCCCCCCEEEEEEHHHHHH
QVLHHDADIGRKKVESAADALRELNPHIIVDTIAKRLDDTELKSLIEQHTIVVDASDNVD
HHHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCHHHHHHHHHHCEEEEECCCCCC
TRNQLNRLCFATKTALISGAAIRMEGQVSVFTYDDPAQPCYQCLSALFGSGALSCVEAGV
HHHHHHHHHHHHHHHHHCCCEEEEECEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
MAPVVGIVGAVQAMEAIKVISDYGQPKKGKILILDALSMSWREMNLMKMPTCPVCN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]