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The map label for this gene is luxQ [H]

Identifier: 156977380

GI number: 156977380

Start: 1341795

End: 1343579

Strand: Reverse

Name: luxQ [H]

Synonym: VIBHAR_06167

Alternate gene names: 156977380

Gene position: 1343579-1341795 (Counterclockwise)

Preceding gene: 156977381

Following gene: 156977377

Centisome position: 60.96

GC content: 43.42

Gene sequence:

>1785_bases
ATGAATAAATTTCGCTTAGCTAACGCCGCCTTGTTCGTCATTATTACCGTGATGGCGGTTCTGGCGTGCATGACTCATGT
TAATTCAAGAAATACTCAAGCGGTATACACATCGCTTTCTGAGATTGGTCACCATTTAATAGAGGCTCGGGATAGCGTGG
TTAATCCCTACTCGATCCGAGAGCGGAGGAATTATGAAATCACGCATAGTTTAGTTGAGCTAGAGCTTGCTTCTGAACAA
TTGATTTCTGATTTCAAACAGTCGATTTGGTTTGATATCACGTCCACTAGGTTACGTGCACAAAGTATCGTTGTTCAGTT
TAATGGCAAAGTTAGAGATGCGACTCAATCGTTAGACATGCTAATTGGTGTCCAGGTTGCAAATCAATACGAATTACTCA
CACTACATAACATTTACAAAGACCAATTTAGCGCCCAAACCGATGATATATGGTTGGAAGAGCATTATTTTGATTTTTTA
ACCAATGCGGCGTTACAAGGTGATAACCCCCAGAGCCAGAGTATCTCATTATTTTTGAATAGACTGCGCCAAAGCGAGCG
CAAGATAGAGTTGCTTACCAACAGGATTCTAGAAGGCCATTACTTTGAGTTTGTTGAGTATTCTGAGCATCAGTTACTTG
AAATCGCGCAACGTGAATCCAGGCTGACGTGGCTGTTTGTTCTCCTGTCCATTATCTTATTAGTGACGGCGTTTGTGCTG
CAAACTCAACATCGTGTGAATAAGCTCAAACATCTCAATGACGAGTTAATAGAAGCGACAGAGAAAGCGGAGCGCGCAGC
CAAAGCGAAGTCACAATTCTTAGCGACCATGAGCCATGAGTTAAGAACACCAATGAATGGGGTATTGGGTATTTCACAAA
TCATTGCCAATGAAACTCAAGAAAAAACAACCAAAGAACATGTGAAAATAATCTTGGACTCCGTCCAGCACCTGATGACG
ATTCTCAATGACATATTGGATTTTTCTAAAGTGGAAGAGAATAGACTGGATTTAGAAGCGGCACCTTTTAATTTGTTGCA
AGTGTTAACTCCCGTTTGTAGCGCGATTCAGCCGCTTGTTGAAGAGAAAAATATCCAGCTTTATGTCGAAAATGAAGTGC
CTGACACTATCGAGTTTAAGGGGGATTGTGCCCGTGTCCGCCAGATCTTGTTTAATCTCGCAGGCAATGCGGTGAAGTTT
ACTGGCGATGGGCACGTATTGATTCGGGCTGAGCTTGATGAGCAAAAGCGATGTCTTCTTATCTCAGTCAATGATACTGG
TATCGGTATTCCGGGAGATAAGCAAGGTTGTATTTTTAACTCGTTTGAACAGGCTGATACTTCTACCACGCGTAAGTTTG
GCGGAACCGGGCTTGGTCTTGCGATTGTCAAAAAGCTCACGGAATTGATGAGTGGAGAGATTAAACTCAAAAGTGTTGAG
AGCATTGGGACTCAGTTTGTAGTGGAGCTTCCTATTCCTTGGATAGAGAAAGAATTGCCAGCAACACAAAACACCCCAGT
TAAGCAACAACGGGAGAGTAAACGTCATCTTCACATTCTCCTTGCGGAAGACAACCGAGTGAACGCGATTGTGGCGAAAG
GCTTTTGTGAGAAGTTAGGACACACGGTTGAGATTGCTGAGAATGGTTTGATTGCGACCAAGAAAGCACAAGAACACCAA
TATGACCTGATATTGATGTCGGATAGGCGACACCTGTTACCAGATGCCGCCCTCCTAAGAACCGTACGTGCAACTTTCAC
TGCATACGGCTCAAGCCTCCACTAA

Upstream 100 bases:

>100_bases
CAGTTGGGGGTAACGATGAGCGACGACAAAGTGGCAGATATCGAAGCCTTCCTGATGACGTTAAGTTCCCCAAGGCCTGC
AATTTTGGAGGTGTTTGAAA

Downstream 100 bases:

>100_bases
GGCGTTATTGTTACCCAGCAACTCACAAAGCAGTGGCGACAGGAGCAAACCATGAGTTACGACCTGTATTTTTCACCTTA
CGTTCATTGAGAAAACCTTC

Product: sensor protein LuxQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MNKFRLANAALFVIITVMAVLACMTHVNSRNTQAVYTSLSEIGHHLIEARDSVVNPYSIRERRNYEITHSLVELELASEQ
LISDFKQSIWFDITSTRLRAQSIVVQFNGKVRDATQSLDMLIGVQVANQYELLTLHNIYKDQFSAQTDDIWLEEHYFDFL
TNAALQGDNPQSQSISLFLNRLRQSERKIELLTNRILEGHYFEFVEYSEHQLLEIAQRESRLTWLFVLLSIILLVTAFVL
QTQHRVNKLKHLNDELIEATEKAERAAKAKSQFLATMSHELRTPMNGVLGISQIIANETQEKTTKEHVKIILDSVQHLMT
ILNDILDFSKVEENRLDLEAAPFNLLQVLTPVCSAIQPLVEEKNIQLYVENEVPDTIEFKGDCARVRQILFNLAGNAVKF
TGDGHVLIRAELDEQKRCLLISVNDTGIGIPGDKQGCIFNSFEQADTSTTRKFGGTGLGLAIVKKLTELMSGEIKLKSVE
SIGTQFVVELPIPWIEKELPATQNTPVKQQRESKRHLHILLAEDNRVNAIVAKGFCEKLGHTVEIAENGLIATKKAQEHQ
YDLILMSDRRHLLPDAALLRTVRATFTAYGSSLH

Sequences:

>Translated_594_residues
MNKFRLANAALFVIITVMAVLACMTHVNSRNTQAVYTSLSEIGHHLIEARDSVVNPYSIRERRNYEITHSLVELELASEQ
LISDFKQSIWFDITSTRLRAQSIVVQFNGKVRDATQSLDMLIGVQVANQYELLTLHNIYKDQFSAQTDDIWLEEHYFDFL
TNAALQGDNPQSQSISLFLNRLRQSERKIELLTNRILEGHYFEFVEYSEHQLLEIAQRESRLTWLFVLLSIILLVTAFVL
QTQHRVNKLKHLNDELIEATEKAERAAKAKSQFLATMSHELRTPMNGVLGISQIIANETQEKTTKEHVKIILDSVQHLMT
ILNDILDFSKVEENRLDLEAAPFNLLQVLTPVCSAIQPLVEEKNIQLYVENEVPDTIEFKGDCARVRQILFNLAGNAVKF
TGDGHVLIRAELDEQKRCLLISVNDTGIGIPGDKQGCIFNSFEQADTSTTRKFGGTGLGLAIVKKLTELMSGEIKLKSVE
SIGTQFVVELPIPWIEKELPATQNTPVKQQRESKRHLHILLAEDNRVNAIVAKGFCEKLGHTVEIAENGLIATKKAQEHQ
YDLILMSDRRHLLPDAALLRTVRATFTAYGSSLH
>Mature_594_residues
MNKFRLANAALFVIITVMAVLACMTHVNSRNTQAVYTSLSEIGHHLIEARDSVVNPYSIRERRNYEITHSLVELELASEQ
LISDFKQSIWFDITSTRLRAQSIVVQFNGKVRDATQSLDMLIGVQVANQYELLTLHNIYKDQFSAQTDDIWLEEHYFDFL
TNAALQGDNPQSQSISLFLNRLRQSERKIELLTNRILEGHYFEFVEYSEHQLLEIAQRESRLTWLFVLLSIILLVTAFVL
QTQHRVNKLKHLNDELIEATEKAERAAKAKSQFLATMSHELRTPMNGVLGISQIIANETQEKTTKEHVKIILDSVQHLMT
ILNDILDFSKVEENRLDLEAAPFNLLQVLTPVCSAIQPLVEEKNIQLYVENEVPDTIEFKGDCARVRQILFNLAGNAVKF
TGDGHVLIRAELDEQKRCLLISVNDTGIGIPGDKQGCIFNSFEQADTSTTRKFGGTGLGLAIVKKLTELMSGEIKLKSVE
SIGTQFVVELPIPWIEKELPATQNTPVKQQRESKRHLHILLAEDNRVNAIVAKGFCEKLGHTVEIAENGLIATKKAQEHQ
YDLILMSDRRHLLPDAALLRTVRATFTAYGSSLH

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=40.9266409266409, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI48994928, Length=329, Percent_Identity=34.0425531914894, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI145693157, Length=460, Percent_Identity=30.6521739130435, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI87081816, Length=289, Percent_Identity=34.9480968858132, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1788713, Length=418, Percent_Identity=28.9473684210526, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=26.8292682926829, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=27.0386266094421, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=298, Percent_Identity=26.8456375838926, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=26.7716535433071, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=26.6949152542373, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=294, Percent_Identity=25.8503401360544, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=221, Percent_Identity=27.1493212669683, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.1101321585903, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790300, Length=354, Percent_Identity=24.0112994350282, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=333, Percent_Identity=23.1231231231231, Blast_Score=62, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322044, Length=147, Percent_Identity=36.0544217687075, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67303; Mature: 67303

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFRLANAALFVIITVMAVLACMTHVNSRNTQAVYTSLSEIGHHLIEARDSVVNPYSIR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ERRNYEITHSLVELELASEQLISDFKQSIWFDITSTRLRAQSIVVQFNGKVRDATQSLDM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHEEEEEEEEECCCHHHHHHHHHH
LIGVQVANQYELLTLHNIYKDQFSAQTDDIWLEEHYFDFLTNAALQGDNPQSQSISLFLN
HHEEEECCCEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RLRQSERKIELLTNRILEGHYFEFVEYSEHQLLEIAQRESRLTWLFVLLSIILLVTAFVL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQHRVNKLKHLNDELIEATEKAERAAKAKSQFLATMSHELRTPMNGVLGISQIIANETQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
EKTTKEHVKIILDSVQHLMTILNDILDFSKVEENRLDLEAAPFNLLQVLTPVCSAIQPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EEKNIQLYVENEVPDTIEFKGDCARVRQILFNLAGNAVKFTGDGHVLIRAELDEQKRCLL
CCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEE
ISVNDTGIGIPGDKQGCIFNSFEQADTSTTRKFGGTGLGLAIVKKLTELMSGEIKLKSVE
EEECCCCCCCCCCCCCCEECCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHH
SIGTQFVVELPIPWIEKELPATQNTPVKQQRESKRHLHILLAEDNRVNAIVAKGFCEKLG
HCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
HTVEIAENGLIATKKAQEHQYDLILMSDRRHLLPDAALLRTVRATFTAYGSSLH
CEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKFRLANAALFVIITVMAVLACMTHVNSRNTQAVYTSLSEIGHHLIEARDSVVNPYSIR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ERRNYEITHSLVELELASEQLISDFKQSIWFDITSTRLRAQSIVVQFNGKVRDATQSLDM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHEEEEEEEEECCCHHHHHHHHHH
LIGVQVANQYELLTLHNIYKDQFSAQTDDIWLEEHYFDFLTNAALQGDNPQSQSISLFLN
HHEEEECCCEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RLRQSERKIELLTNRILEGHYFEFVEYSEHQLLEIAQRESRLTWLFVLLSIILLVTAFVL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQHRVNKLKHLNDELIEATEKAERAAKAKSQFLATMSHELRTPMNGVLGISQIIANETQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
EKTTKEHVKIILDSVQHLMTILNDILDFSKVEENRLDLEAAPFNLLQVLTPVCSAIQPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EEKNIQLYVENEVPDTIEFKGDCARVRQILFNLAGNAVKFTGDGHVLIRAELDEQKRCLL
CCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEE
ISVNDTGIGIPGDKQGCIFNSFEQADTSTTRKFGGTGLGLAIVKKLTELMSGEIKLKSVE
EEECCCCCCCCCCCCCCEECCHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHH
SIGTQFVVELPIPWIEKELPATQNTPVKQQRESKRHLHILLAEDNRVNAIVAKGFCEKLG
HCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
HTVEIAENGLIATKKAQEHQYDLILMSDRRHLLPDAALLRTVRATFTAYGSSLH
CEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]