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The map label for this gene is bhuA [H]

Identifier: 156977328

GI number: 156977328

Start: 1275614

End: 1277086

Strand: Direct

Name: bhuA [H]

Synonym: VIBHAR_06114

Alternate gene names: 156977328

Gene position: 1275614-1277086 (Clockwise)

Preceding gene: 156977327

Following gene: 156977329

Centisome position: 57.88

GC content: 46.71

Gene sequence:

>1473_bases
ATGGAGGTTACGGTGTCCGCTTCAACCGTATTTAAGTTAAGCCCACTTACCATCGCCCTTTTCGTCGCTTCCCAAGTGAC
TTACGCCAACGATGACATGGAAGTGATGGAGGTGCTAGGCCACACTCCGGAAGGAATCGATATTACGATTGACTCCGATC
AGCTCGCCAAATCACAGGCACAAGATCTGAATGACATTTTCCGTAAAGATGCAGAAATTAGTGTTGGTGGCTCTTCTGGT
GTTTCTCAAAAGATCTATGTCCGTGGTCTGGAAGATACCATGTTGAATGTGTCTATCGACGGCGCGGCACAATCCGGTAA
CCTATTCCATCACCAAGGTCGATTATCTATCGAGCCTGAACTGCTCAAGCAAGTTGATGTTAGCGCGGGAGCAGGACGAG
CAACAGATGGCCCAGGAGCATTGGGTGGCGCTATAAAGTTCACCACTAAAGACGCACATGACCTCCTTACTGCAGGTGAA
ACCTACGGCGCTATGCTCAAAGGCGGTTACTACACCAATAATGAAGGTTACAAAGTTTCGGCAAGTTTGTATGGAGAAGT
CGCCGATCAGCTTGGCCTACTTGCATCATTTGGTTACGTCGACGGGGATAACATCGAAGACGGCAAAGGCCAGGAGCAGC
CGTACACTGCGTTAGAACAGCAAGTTGCGATCCTTAAGCTATCCGGTCAACTCAACGACGAACACTACCTCTCGGTAAGC
TACGACTATCGTAATGATGATGGCCGTCGCTTAAATCGCCCCCACTTCCAACCAAGCTTTAAAAATGCGCCTCTCGATCA
AGAAACCGATCGTTCTACTTTTACGCTTAACCACAAATACAACGCAAGCGACCTTTTCAATCTCGACACCACTTTCTACT
ACACCGATAGCCGCTTAGCTCATAAAGATCACCCTCGCTGGGGCACCAGTGATGGCTCAATTCAAACGTCCGGCGTAAAG
ATCTTCAATACGAGCAAATTAACAGGCCATACCTTGGTTTACGGTTTGGATTACAAGAAAGACAAATCTGAGTTTGAAAC
CAACTACGATGGTAAAAAAAACGATGAGGAGAAAGGCACCGTTTACGGCTTGTTTGTTCAAGATGATTGGATGCTAACAG
AAACCATCATTCTTACCGCTGGTGCTCGTTATGACTGGTATGAGCTTACTGATAACATGGAGCAAGACTTCGATTCGAGC
GGCTTTAGCCCTAACGTGGGTATTAATTACAATCCGTTGGAAGGTTTGAACCTATTTGCTAGTTATGCAGAAGCGTTTCG
TGGCCAACAAATCAAAGAACTGTTTGTCATCGACTACCGCGAAAACGACCCAAATCGTAAGCCTGAAGAAGCACGTAACT
TAGAGCTAGGGGCAAATTACCAATACGATGATTTCTTCGCTGGCATCACATTCTTTGATAGTACAATCAAAGACGTGGTA
ACAAACCAAGGCCTGAGGGCTCCCCACAACTAG

Upstream 100 bases:

>100_bases
TTAACGTCTGCTGACTACAAGGATTGTAACAGTTGTAAAAGTCGTTTACTCAGAGTGGAAGAATCACCAAAATCTCACTC
GATAATAATTCTCATTAACA

Downstream 100 bases:

>100_bases
CATAGAAGAATCATGTAGATAGCGTGAAAAGTAGGCAGATTCATTTTGATCGGCGATTATAGCATCAATTGAAAAGATAT
GACCCGACGAGTCTCATGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Brucella heme uptake protein A [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MEVTVSASTVFKLSPLTIALFVASQVTYANDDMEVMEVLGHTPEGIDITIDSDQLAKSQAQDLNDIFRKDAEISVGGSSG
VSQKIYVRGLEDTMLNVSIDGAAQSGNLFHHQGRLSIEPELLKQVDVSAGAGRATDGPGALGGAIKFTTKDAHDLLTAGE
TYGAMLKGGYYTNNEGYKVSASLYGEVADQLGLLASFGYVDGDNIEDGKGQEQPYTALEQQVAILKLSGQLNDEHYLSVS
YDYRNDDGRRLNRPHFQPSFKNAPLDQETDRSTFTLNHKYNASDLFNLDTTFYYTDSRLAHKDHPRWGTSDGSIQTSGVK
IFNTSKLTGHTLVYGLDYKKDKSEFETNYDGKKNDEEKGTVYGLFVQDDWMLTETIILTAGARYDWYELTDNMEQDFDSS
GFSPNVGINYNPLEGLNLFASYAEAFRGQQIKELFVIDYRENDPNRKPEEARNLELGANYQYDDFFAGITFFDSTIKDVV
TNQGLRAPHN

Sequences:

>Translated_490_residues
MEVTVSASTVFKLSPLTIALFVASQVTYANDDMEVMEVLGHTPEGIDITIDSDQLAKSQAQDLNDIFRKDAEISVGGSSG
VSQKIYVRGLEDTMLNVSIDGAAQSGNLFHHQGRLSIEPELLKQVDVSAGAGRATDGPGALGGAIKFTTKDAHDLLTAGE
TYGAMLKGGYYTNNEGYKVSASLYGEVADQLGLLASFGYVDGDNIEDGKGQEQPYTALEQQVAILKLSGQLNDEHYLSVS
YDYRNDDGRRLNRPHFQPSFKNAPLDQETDRSTFTLNHKYNASDLFNLDTTFYYTDSRLAHKDHPRWGTSDGSIQTSGVK
IFNTSKLTGHTLVYGLDYKKDKSEFETNYDGKKNDEEKGTVYGLFVQDDWMLTETIILTAGARYDWYELTDNMEQDFDSS
GFSPNVGINYNPLEGLNLFASYAEAFRGQQIKELFVIDYRENDPNRKPEEARNLELGANYQYDDFFAGITFFDSTIKDVV
TNQGLRAPHN
>Mature_490_residues
MEVTVSASTVFKLSPLTIALFVASQVTYANDDMEVMEVLGHTPEGIDITIDSDQLAKSQAQDLNDIFRKDAEISVGGSSG
VSQKIYVRGLEDTMLNVSIDGAAQSGNLFHHQGRLSIEPELLKQVDVSAGAGRATDGPGALGGAIKFTTKDAHDLLTAGE
TYGAMLKGGYYTNNEGYKVSASLYGEVADQLGLLASFGYVDGDNIEDGKGQEQPYTALEQQVAILKLSGQLNDEHYLSVS
YDYRNDDGRRLNRPHFQPSFKNAPLDQETDRSTFTLNHKYNASDLFNLDTTFYYTDSRLAHKDHPRWGTSDGSIQTSGVK
IFNTSKLTGHTLVYGLDYKKDKSEFETNYDGKKNDEEKGTVYGLFVQDDWMLTETIILTAGARYDWYELTDNMEQDFDSS
GFSPNVGINYNPLEGLNLFASYAEAFRGQQIKELFVIDYRENDPNRKPEEARNLELGANYQYDDFFAGITFFDSTIKDVV
TNQGLRAPHN

Specific function: Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 54416; Mature: 54416

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTVSASTVFKLSPLTIALFVASQVTYANDDMEVMEVLGHTPEGIDITIDSDQLAKSQA
CEEEEECCEEEEECCCEEEEEEHHHEEECCCCHHHHHHHCCCCCCEEEEECCHHHHHHHH
QDLNDIFRKDAEISVGGSSGVSQKIYVRGLEDTMLNVSIDGAAQSGNLFHHQGRLSIEPE
HHHHHHHHCCCEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEECCCCCCCHH
LLKQVDVSAGAGRATDGPGALGGAIKFTTKDAHDLLTAGETYGAMLKGGYYTNNEGYKVS
HHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCHHHHHEECCEEECCCCEEEE
ASLYGEVADQLGLLASFGYVDGDNIEDGKGQEQPYTALEQQVAILKLSGQLNDEHYLSVS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCCCEEEEEE
YDYRNDDGRRLNRPHFQPSFKNAPLDQETDRSTFTLNHKYNASDLFNLDTTFYYTDSRLA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCEEEEEECCCCC
HKDHPRWGTSDGSIQTSGVKIFNTSKLTGHTLVYGLDYKKDKSEFETNYDGKKNDEEKGT
CCCCCCCCCCCCCEEECCEEEEECCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCC
VYGLFVQDDWMLTETIILTAGARYDWYELTDNMEQDFDSSGFSPNVGINYNPLEGLNLFA
EEEEEEECCCEEEEEEEEECCCCCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHH
SYAEAFRGQQIKELFVIDYRENDPNRKPEEARNLELGANYQYDDFFAGITFFDSTIKDVV
HHHHHHCCCCEEEEEEEEEECCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHH
TNQGLRAPHN
HCCCCCCCCC
>Mature Secondary Structure
MEVTVSASTVFKLSPLTIALFVASQVTYANDDMEVMEVLGHTPEGIDITIDSDQLAKSQA
CEEEEECCEEEEECCCEEEEEEHHHEEECCCCHHHHHHHCCCCCCEEEEECCHHHHHHHH
QDLNDIFRKDAEISVGGSSGVSQKIYVRGLEDTMLNVSIDGAAQSGNLFHHQGRLSIEPE
HHHHHHHHCCCEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCEEEECCCCCCCHH
LLKQVDVSAGAGRATDGPGALGGAIKFTTKDAHDLLTAGETYGAMLKGGYYTNNEGYKVS
HHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCHHHHHEECCEEECCCCEEEE
ASLYGEVADQLGLLASFGYVDGDNIEDGKGQEQPYTALEQQVAILKLSGQLNDEHYLSVS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCCCEEEEEE
YDYRNDDGRRLNRPHFQPSFKNAPLDQETDRSTFTLNHKYNASDLFNLDTTFYYTDSRLA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCEEEEEECCCCC
HKDHPRWGTSDGSIQTSGVKIFNTSKLTGHTLVYGLDYKKDKSEFETNYDGKKNDEEKGT
CCCCCCCCCCCCCEEECCEEEEECCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCC
VYGLFVQDDWMLTETIILTAGARYDWYELTDNMEQDFDSSGFSPNVGINYNPLEGLNLFA
EEEEEEECCCEEEEEEEEECCCCCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHH
SYAEAFRGQQIKELFVIDYRENDPNRKPEEARNLELGANYQYDDFFAGITFFDSTIKDVV
HHHHHHCCCCEEEEEEEEEECCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHH
TNQGLRAPHN
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA