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The map label for this gene is ribD [H]

Identifier: 156977316

GI number: 156977316

Start: 1265102

End: 1265707

Strand: Reverse

Name: ribD [H]

Synonym: VIBHAR_06102

Alternate gene names: 156977316

Gene position: 1265707-1265102 (Counterclockwise)

Preceding gene: 156977317

Following gene: 156977311

Centisome position: 57.43

GC content: 46.86

Gene sequence:

>606_bases
GTGGTAATCAACGGGGCAACTTCGGTTCGCCCCGTTTTATTTTTAGTGAAAATCATAAAGGGATTGATTTGTTTGGAAAG
GCCAAACGTAAGAGCTATGCAAGCACTCTTATATGGCGAGGAAAGCATGCTGGCGTTAGAATCCATCACCCAAATTTTGA
ATAACGAGTATCAGATCCAAATGAGCCAACAATTTATGCTTCGTGCGTTGGAAGTGTCACTCAACGCGCTGCCTGCTTGT
CAACCAAACCCACCTGTTGGTTGCGTGCTGGTCAAAGACGGTGAAATCGTATCAGAGGGGCATACACAGGCGATTGGTGG
TAATCATGCAGAAGTTGAAGCTCTCAAGGCTTACAAGGGCGATCTAAGTGACGTAACCGCGTATGTAACACTAGAGCCGT
GTTCGTTTGTTGGACGTACACCTGCTTGCGCTAAAACCCTAGTGACTTGCGGCATCAAAAAAGTGGTGGTTGCCATGTTA
GATCCTGACCCGCGTAACGCTGGTCGTGGTATTGATATCCTAAAAGAAGGTGGCGTAGAAGTTGAAATTGGTTTGTGCGG
TGAAGAGGCGAGTGCGTTCCTGTCGCCTTACTTAGGAAAGTCATAA

Upstream 100 bases:

>100_bases
ACAGGCACACATGGAGTTGAACAAAGCATTGGCACAACTTCGTGCAGTAGAACTAACGATGAGAATTCGTTAGTCACTTT
TTCGGAATGCGGTCTGAAGA

Downstream 100 bases:

>100_bases
CCTTACGTTGGTTAGGTTTCTCTAAAGCCTCGAAATCCCGAAGAGCGACATGGATATCATGCCGCTCTCAGAAGTAGCTC
GTCTAATTTATTATTGACCA

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MVINGATSVRPVLFLVKIIKGLICLERPNVRAMQALLYGEESMLALESITQILNNEYQIQMSQQFMLRALEVSLNALPAC
QPNPPVGCVLVKDGEIVSEGHTQAIGGNHAEVEALKAYKGDLSDVTAYVTLEPCSFVGRTPACAKTLVTCGIKKVVVAML
DPDPRNAGRGIDILKEGGVEVEIGLCGEEASAFLSPYLGKS

Sequences:

>Translated_201_residues
MVINGATSVRPVLFLVKIIKGLICLERPNVRAMQALLYGEESMLALESITQILNNEYQIQMSQQFMLRALEVSLNALPAC
QPNPPVGCVLVKDGEIVSEGHTQAIGGNHAEVEALKAYKGDLSDVTAYVTLEPCSFVGRTPACAKTLVTCGIKKVVVAML
DPDPRNAGRGIDILKEGGVEVEIGLCGEEASAFLSPYLGKS
>Mature_201_residues
MVINGATSVRPVLFLVKIIKGLICLERPNVRAMQALLYGEESMLALESITQILNNEYQIQMSQQFMLRALEVSLNALPAC
QPNPPVGCVLVKDGEIVSEGHTQAIGGNHAEVEALKAYKGDLSDVTAYVTLEPCSFVGRTPACAKTLVTCGIKKVVVAML
DPDPRNAGRGIDILKEGGVEVEIGLCGEEASAFLSPYLGKS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=136, Percent_Identity=46.3235294117647, Blast_Score=126, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 21473; Mature: 21473

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINGATSVRPVLFLVKIIKGLICLERPNVRAMQALLYGEESMLALESITQILNNEYQIQ
CEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
MSQQFMLRALEVSLNALPACQPNPPVGCVLVKDGEIVSEGHTQAIGGNHAEVEALKAYKG
EHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHCC
DLSDVTAYVTLEPCSFVGRTPACAKTLVTCGIKKVVVAMLDPDPRNAGRGIDILKEGGVE
CCCCEEEEEEECCHHHCCCCHHHHHHHHHHCHHHHEEEEECCCCCCCCCCCEEEECCCCE
VEIGLCGEEASAFLSPYLGKS
EEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure
MVINGATSVRPVLFLVKIIKGLICLERPNVRAMQALLYGEESMLALESITQILNNEYQIQ
CEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
MSQQFMLRALEVSLNALPACQPNPPVGCVLVKDGEIVSEGHTQAIGGNHAEVEALKAYKG
EHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCHHHHHHHHHCC
DLSDVTAYVTLEPCSFVGRTPACAKTLVTCGIKKVVVAMLDPDPRNAGRGIDILKEGGVE
CCCCEEEEEEECCHHHCCCCHHHHHHHHHHCHHHHEEEEECCCCCCCCCCCEEEECCCCE
VEIGLCGEEASAFLSPYLGKS
EEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]