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The map label for this gene is yieH [H]

Identifier: 156977152

GI number: 156977152

Start: 1123286

End: 1123999

Strand: Reverse

Name: yieH [H]

Synonym: VIBHAR_05938

Alternate gene names: 156977152

Gene position: 1123999-1123286 (Counterclockwise)

Preceding gene: 156977153

Following gene: 156977151

Centisome position: 51.0

GC content: 45.52

Gene sequence:

>714_bases
TTGTTCAACGAATGGTTTGAGATATTTGTTGGCGGGGGAAGGCGTATGGCTATCAACAATATTAAGTGCGTCATATTCGA
TTGTGACGGTACGCTGGTCGACAGCGAAAGCCTGTGTTGCCATGCATTGGTTAATGTGTTTGAGCAATACGGCGTAGAGA
TGAGTTTTGAAGAGTGTGTTGCACATTTCAAAGGTGGCAAGTTGGCCGATATCCTGCGTGATGCCAAAGCGTTCATGAAC
GTTAATGTGTCTATTGATGTTCTTGAACCACAATACCGTGAGGAGCTACAGAAGCTGTTTGTCCGCCACCTAAAACCAAT
GGATGGCGCAAAGCGTCTTATTCAATTCTTGGATTCACACAACATCGAGTATTGTGTGGCTTCTAATGGACCGAAAGACA
AGATCGAATACTCGCTTGAGCTAACAGGGCTGCTAGATGCGTTTAAAGGAAAAGTCTTTTCTGCTTTCGACGCGAATAGT
TGGAAGCCAGAGCCTGATTTGATCATGTATAGCGCGATGAATATGGGTTTTCTGCCAAGCGATTGTTTGTATATTGATGA
CACCCCAAAGGGCGTTGAGGCTGGATTAAACGCAGGTGTGAAAACGGTGCAGCTTTACAACGGCGCGCCAATCAACCGAG
TGGGAGACGAGCGCGTTATCCGAATTCATCATCTTGACGAACTAAAAGAGCAGCTCTTAGGCTGCTCAATTTAA

Upstream 100 bases:

>100_bases
TCTACGAAATGCCAAGTCTGTCGTTTAAACATTTCAAAACTTACCTATTATGTTGATACATATTTAGTACAAATAAATAA
GTTAATAAGAACAACGTTAA

Downstream 100 bases:

>100_bases
TGACAAACGTTACTCAAGCTATGGATATGTTTGAATTTGGCTTGTAGCAACGGAGTTTGGTGTAAGCATTGGATGGAAGA
GAAGTTTTTCGTATGGAACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MFNEWFEIFVGGGRRMAINNIKCVIFDCDGTLVDSESLCCHALVNVFEQYGVEMSFEECVAHFKGGKLADILRDAKAFMN
VNVSIDVLEPQYREELQKLFVRHLKPMDGAKRLIQFLDSHNIEYCVASNGPKDKIEYSLELTGLLDAFKGKVFSAFDANS
WKPEPDLIMYSAMNMGFLPSDCLYIDDTPKGVEAGLNAGVKTVQLYNGAPINRVGDERVIRIHHLDELKEQLLGCSI

Sequences:

>Translated_237_residues
MFNEWFEIFVGGGRRMAINNIKCVIFDCDGTLVDSESLCCHALVNVFEQYGVEMSFEECVAHFKGGKLADILRDAKAFMN
VNVSIDVLEPQYREELQKLFVRHLKPMDGAKRLIQFLDSHNIEYCVASNGPKDKIEYSLELTGLLDAFKGKVFSAFDANS
WKPEPDLIMYSAMNMGFLPSDCLYIDDTPKGVEAGLNAGVKTVQLYNGAPINRVGDERVIRIHHLDELKEQLLGCSI
>Mature_237_residues
MFNEWFEIFVGGGRRMAINNIKCVIFDCDGTLVDSESLCCHALVNVFEQYGVEMSFEECVAHFKGGKLADILRDAKAFMN
VNVSIDVLEPQYREELQKLFVRHLKPMDGAKRLIQFLDSHNIEYCVASNGPKDKIEYSLELTGLLDAFKGKVFSAFDANS
WKPEPDLIMYSAMNMGFLPSDCLYIDDTPKGVEAGLNAGVKTVQLYNGAPINRVGDERVIRIHHLDELKEQLLGCSI

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=214, Percent_Identity=34.1121495327103, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87082080, Length=209, Percent_Identity=26.7942583732057, Blast_Score=63, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137324, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550911, Length=233, Percent_Identity=25.7510729613734, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 26669; Mature: 26669

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEWFEIFVGGGRRMAINNIKCVIFDCDGTLVDSESLCCHALVNVFEQYGVEMSFEECV
CCCCEEEEEECCCCEEEECCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHH
AHFKGGKLADILRDAKAFMNVNVSIDVLEPQYREELQKLFVRHLKPMDGAKRLIQFLDSH
HHHCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
NIEYCVASNGPKDKIEYSLELTGLLDAFKGKVFSAFDANSWKPEPDLIMYSAMNMGFLPS
CCEEEEECCCCCCCEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCCCCCC
DCLYIDDTPKGVEAGLNAGVKTVQLYNGAPINRVGDERVIRIHHLDELKEQLLGCSI
CCEEECCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHCCCC
>Mature Secondary Structure
MFNEWFEIFVGGGRRMAINNIKCVIFDCDGTLVDSESLCCHALVNVFEQYGVEMSFEECV
CCCCEEEEEECCCCEEEECCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHH
AHFKGGKLADILRDAKAFMNVNVSIDVLEPQYREELQKLFVRHLKPMDGAKRLIQFLDSH
HHHCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
NIEYCVASNGPKDKIEYSLELTGLLDAFKGKVFSAFDANSWKPEPDLIMYSAMNMGFLPS
CCEEEEECCCCCCCEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCCCCCC
DCLYIDDTPKGVEAGLNAGVKTVQLYNGAPINRVGDERVIRIHHLDELKEQLLGCSI
CCEEECCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]