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The map label for this gene is kipI [H]

Identifier: 156977011

GI number: 156977011

Start: 983404

End: 984096

Strand: Direct

Name: kipI [H]

Synonym: VIBHAR_05796

Alternate gene names: 156977011

Gene position: 983404-984096 (Clockwise)

Preceding gene: 156977010

Following gene: 156977012

Centisome position: 44.62

GC content: 44.44

Gene sequence:

>693_bases
ATGAATCAAGGGCAGTTTTCTATCTCTCCCATTTCTGAATGCAGCATCTTAATTCGATTCGACGACACCATTACTGTCGA
ACATATTGGTGAATTAGCGCATCAGATTGTCGATAAGCTCAAACTTATTGTTATGAACGTGGTTCCTTCTTATCGAACCA
TATTGATCGATTACTTGCCCTTTAGAATTCAAGAATCCACGATTCTGCAGGATCTCAATCAAATCGTCAGCCGGTTTGAT
GTCCAGTCAATGGCCAACAAGCAACCGAACTATATTTCTATCCCCGTTTATTATTCGCAAGAAACCGCTCTAGATTTTGC
GCGCTTCGAACAAAACGGATTATCGATGAATCAACTCATTGAGTTACATACTAAACCAGTTTATACCGTTTCGGCGATTG
GGTTTGCCCCTGGGTTTGCTTTTCTCTCTGACGTTACCCAAAAGCTGCAAATGCCAAGGCATCAAACACCTCGAACCCAT
GTTCCTGCGGGCAGTGTTGCCATTGCTGACAGTAAAACCGCAGTCTATCCAGCAGACAGCCCTGGTGGGTGGAATATCAT
AGGCCGCACGCCAATTTCGCTATTCACTGATACCCCTCCCTTCATTCCATTTGAGGTGGGTGACAAGGTCACGTTTGGTT
CGATATCCAAGCAGGAATTTGTGAATTTAGGAGGCGTTTTATGCGCTTCGTAG

Upstream 100 bases:

>100_bases
TTCTTCTAGAAGCCGACACAATTTGTGTCCATGGGGATAACAACGAATCCATCGCTCTCGTTCAAAAGATTCGTCAAAGT
CTCTACACCGGAGGAAATTA

Downstream 100 bases:

>100_bases
GTTTATTGGTAGAAAAGCCAGGCCCGCTCTCTTTGATTCAAGATTTCGGTCGCTTCGGGTTAGCACACATCGGTATCACT
CAAAGTGGACCAGTCGATGA

Product: allophanate hydrolase, subunit 1

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNQGQFSISPISECSILIRFDDTITVEHIGELAHQIVDKLKLIVMNVVPSYRTILIDYLPFRIQESTILQDLNQIVSRFD
VQSMANKQPNYISIPVYYSQETALDFARFEQNGLSMNQLIELHTKPVYTVSAIGFAPGFAFLSDVTQKLQMPRHQTPRTH
VPAGSVAIADSKTAVYPADSPGGWNIIGRTPISLFTDTPPFIPFEVGDKVTFGSISKQEFVNLGGVLCAS

Sequences:

>Translated_230_residues
MNQGQFSISPISECSILIRFDDTITVEHIGELAHQIVDKLKLIVMNVVPSYRTILIDYLPFRIQESTILQDLNQIVSRFD
VQSMANKQPNYISIPVYYSQETALDFARFEQNGLSMNQLIELHTKPVYTVSAIGFAPGFAFLSDVTQKLQMPRHQTPRTH
VPAGSVAIADSKTAVYPADSPGGWNIIGRTPISLFTDTPPFIPFEVGDKVTFGSISKQEFVNLGGVLCAS
>Mature_230_residues
MNQGQFSISPISECSILIRFDDTITVEHIGELAHQIVDKLKLIVMNVVPSYRTILIDYLPFRIQESTILQDLNQIVSRFD
VQSMANKQPNYISIPVYYSQETALDFARFEQNGLSMNQLIELHTKPVYTVSAIGFAPGFAFLSDVTQKLQMPRHQTPRTH
VPAGSVAIADSKTAVYPADSPGGWNIIGRTPISLFTDTPPFIPFEVGDKVTFGSISKQEFVNLGGVLCAS

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=209, Percent_Identity=33.4928229665072, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 25511; Mature: 25511

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQGQFSISPISECSILIRFDDTITVEHIGELAHQIVDKLKLIVMNVVPSYRTILIDYLP
CCCCCEEECCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FRIQESTILQDLNQIVSRFDVQSMANKQPNYISIPVYYSQETALDFARFEQNGLSMNQLI
CEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCCCHHHHH
ELHTKPVYTVSAIGFAPGFAFLSDVTQKLQMPRHQTPRTHVPAGSVAIADSKTAVYPADS
HHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEECCCC
PGGWNIIGRTPISLFTDTPPFIPFEVGDKVTFGSISKQEFVNLGGVLCAS
CCCCEEEECCCEEEECCCCCCCEEECCCEEEECCCCHHHHHHCCCEEECC
>Mature Secondary Structure
MNQGQFSISPISECSILIRFDDTITVEHIGELAHQIVDKLKLIVMNVVPSYRTILIDYLP
CCCCCEEECCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FRIQESTILQDLNQIVSRFDVQSMANKQPNYISIPVYYSQETALDFARFEQNGLSMNQLI
CEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCCCHHHHH
ELHTKPVYTVSAIGFAPGFAFLSDVTQKLQMPRHQTPRTHVPAGSVAIADSKTAVYPADS
HHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEECCCC
PGGWNIIGRTPISLFTDTPPFIPFEVGDKVTFGSISKQEFVNLGGVLCAS
CCCCEEEECCCEEEECCCCCCCEEECCCEEEECCCCHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]