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The map label for this gene is dcuB [H]

Identifier: 156976906

GI number: 156976906

Start: 893689

End: 895020

Strand: Reverse

Name: dcuB [H]

Synonym: VIBHAR_05690

Alternate gene names: 156976906

Gene position: 895020-893689 (Counterclockwise)

Preceding gene: 156976908

Following gene: 156976904

Centisome position: 40.61

GC content: 48.05

Gene sequence:

>1332_bases
ATGTTGTATCTTGAGTTTCTATTTTTGCTCGTGATGCTGTATATCGGCTCACGGTATGGCGGCATTGGTCTTGGTGTCGT
TTCTGGTATTGGTCTGGTGATTGAGGTTTTCATCTTCAAGATGCCTCCAACGTCTCCGCCAGTGACCGTAATGCTGATCA
TCCTCGCGGTGGTCACTTGTGCCTCCATTCTTGAAGCCGCAGGTGGCTTAAAATACATGTTGCAGGTGGCAGAACGCGTA
CTACGTAAGAACCCCAAGCGCGTCACTCTTATTGCACCGTTCGTAACTTACTTTATGACCTTCCTACTTGGCACTGGTCA
CGCGGTTTACTCCATCATGCCAATCATTGGCGACGTTGCGCTGAAAAACGGCATTCGCCCTGAGCGCCCGATGGCTGCGG
CATCGGTTGCCTCTCAAATCGCCATTACAGCATCACCGATTTCGGCGGCAGTGGTTTACTACCTAGCGCAGCTTTCTGAC
ATTCAACACGAAATTACCTTGCTATCGATTCTTCTTGTCACAGTGCCTGCGACCTTGTTCGGTACATTGCTGATGTCTCT
TTACAGCTTGAAACGCGGCAAAGAGCTTGAAGACGATGAAGAGTATCAAGAGCGTCTGAAAGATCCGGTTTGGCGCGACA
AGATCTTAAACACAACGACAACCTCTTTGGATGAAGTACTGCCGTCTAGTGCTCGTAACTCTGTTCTGCTGTTCATCCTA
TCGATTCTTGTGATTGTCGTTATCGCGATGTGGCCAGAAGTCCGTACCATCGCTGAAGGCTCCAAGCCAATCAGTATGGC
AGTTGTGATTCAAATGATGATGCTCTGCTTCGGTGGTATCATTTTGCTAGCGACTAAGACCGATCCTCGCGACGTACCAA
ATGGCGTGGTGTTCAAATCAGGTATGGTTGCAGCGATTGCGATCTTCGGTATTGCATGGATGTCAGATACCTACTTTCAA
TACGCAATGCCTCAGTTTAAGTCAGGCATCGTAGAGATGGTAACCAACTACCCTTGGACATTCGCACTAGCACTATTCAT
TGTGTCTGTTGTGGTGAACTCTCAAGCAGCGACAGCTCGTATGATGTTACCAGTCGGTTTAGGTCTAGGTTTGGAGCCTG
CACTGCTTATCGGCTTGATGCCAGCGGTTTACGGCTACTTCTTTATTCCAAACTACCCTTCAGATATCGCGACTGTGAAC
TTCGATACCTCAGGTACTACTAAGATTGGCAAGTGGTACTTCAACCACTCATTCATGTCTGTGGGTTTAGTCGGCGTGAT
TGGTGCGTGTTGTTTGGGTTACTTGTTAGGGCAAATGATCATTCCGTCATAA

Upstream 100 bases:

>100_bases
CATTGCTGTTTCTTATAAAATGGAATGTGAACAAGGCTAAGTATTTTTTCCTTCAATACCGAAACAATAGAAGTCCCTGT
TTCTAATAAGGAAATTAAAC

Downstream 100 bases:

>100_bases
CCTATTCATCAGACAGCATATGGGGCGAGTCATTGTACGTTTGCGTACAGCCTGAAGTGACTCGCCCTTTCTTCTTTCTC
GAAGCTATACCGTGAGGAGA

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLYLEFLFLLVMLYIGSRYGGIGLGVVSGIGLVIEVFIFKMPPTSPPVTVMLIILAVVTCASILEAAGGLKYMLQVAERV
LRKNPKRVTLIAPFVTYFMTFLLGTGHAVYSIMPIIGDVALKNGIRPERPMAAASVASQIAITASPISAAVVYYLAQLSD
IQHEITLLSILLVTVPATLFGTLLMSLYSLKRGKELEDDEEYQERLKDPVWRDKILNTTTTSLDEVLPSSARNSVLLFIL
SILVIVVIAMWPEVRTIAEGSKPISMAVVIQMMMLCFGGIILLATKTDPRDVPNGVVFKSGMVAAIAIFGIAWMSDTYFQ
YAMPQFKSGIVEMVTNYPWTFALALFIVSVVVNSQAATARMMLPVGLGLGLEPALLIGLMPAVYGYFFIPNYPSDIATVN
FDTSGTTKIGKWYFNHSFMSVGLVGVIGACCLGYLLGQMIIPS

Sequences:

>Translated_443_residues
MLYLEFLFLLVMLYIGSRYGGIGLGVVSGIGLVIEVFIFKMPPTSPPVTVMLIILAVVTCASILEAAGGLKYMLQVAERV
LRKNPKRVTLIAPFVTYFMTFLLGTGHAVYSIMPIIGDVALKNGIRPERPMAAASVASQIAITASPISAAVVYYLAQLSD
IQHEITLLSILLVTVPATLFGTLLMSLYSLKRGKELEDDEEYQERLKDPVWRDKILNTTTTSLDEVLPSSARNSVLLFIL
SILVIVVIAMWPEVRTIAEGSKPISMAVVIQMMMLCFGGIILLATKTDPRDVPNGVVFKSGMVAAIAIFGIAWMSDTYFQ
YAMPQFKSGIVEMVTNYPWTFALALFIVSVVVNSQAATARMMLPVGLGLGLEPALLIGLMPAVYGYFFIPNYPSDIATVN
FDTSGTTKIGKWYFNHSFMSVGLVGVIGACCLGYLLGQMIIPS
>Mature_443_residues
MLYLEFLFLLVMLYIGSRYGGIGLGVVSGIGLVIEVFIFKMPPTSPPVTVMLIILAVVTCASILEAAGGLKYMLQVAERV
LRKNPKRVTLIAPFVTYFMTFLLGTGHAVYSIMPIIGDVALKNGIRPERPMAAASVASQIAITASPISAAVVYYLAQLSD
IQHEITLLSILLVTVPATLFGTLLMSLYSLKRGKELEDDEEYQERLKDPVWRDKILNTTTTSLDEVLPSSARNSVLLFIL
SILVIVVIAMWPEVRTIAEGSKPISMAVVIQMMMLCFGGIILLATKTDPRDVPNGVVFKSGMVAAIAIFGIAWMSDTYFQ
YAMPQFKSGIVEMVTNYPWTFALALFIVSVVVNSQAATARMMLPVGLGLGLEPALLIGLMPAVYGYFFIPNYPSDIATVN
FDTSGTTKIGKWYFNHSFMSVGLVGVIGACCLGYLLGQMIIPS

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=406, Percent_Identity=45.8128078817734, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1790580, Length=448, Percent_Identity=36.3839285714286, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 48192; Mature: 48192

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLEFLFLLVMLYIGSRYGGIGLGVVSGIGLVIEVFIFKMPPTSPPVTVMLIILAVVTC
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASILEAAGGLKYMLQVAERVLRKNPKRVTLIAPFVTYFMTFLLGTGHAVYSIMPIIGDVA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKNGIRPERPMAAASVASQIAITASPISAAVVYYLAQLSDIQHEITLLSILLVTVPATLF
HHCCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLLMSLYSLKRGKELEDDEEYQERLKDPVWRDKILNTTTTSLDEVLPSSARNSVLLFIL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHH
SILVIVVIAMWPEVRTIAEGSKPISMAVVIQMMMLCFGGIILLATKTDPRDVPNGVVFKS
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECC
GMVAAIAIFGIAWMSDTYFQYAMPQFKSGIVEMVTNYPWTFALALFIVSVVVNSQAATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHH
MMLPVGLGLGLEPALLIGLMPAVYGYFFIPNYPSDIATVNFDTSGTTKIGKWYFNHSFMS
HHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
VGLVGVIGACCLGYLLGQMIIPS
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYLEFLFLLVMLYIGSRYGGIGLGVVSGIGLVIEVFIFKMPPTSPPVTVMLIILAVVTC
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASILEAAGGLKYMLQVAERVLRKNPKRVTLIAPFVTYFMTFLLGTGHAVYSIMPIIGDVA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKNGIRPERPMAAASVASQIAITASPISAAVVYYLAQLSDIQHEITLLSILLVTVPATLF
HHCCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLLMSLYSLKRGKELEDDEEYQERLKDPVWRDKILNTTTTSLDEVLPSSARNSVLLFIL
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHH
SILVIVVIAMWPEVRTIAEGSKPISMAVVIQMMMLCFGGIILLATKTDPRDVPNGVVFKS
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECC
GMVAAIAIFGIAWMSDTYFQYAMPQFKSGIVEMVTNYPWTFALALFIVSVVVNSQAATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHH
MMLPVGLGLGLEPALLIGLMPAVYGYFFIPNYPSDIATVNFDTSGTTKIGKWYFNHSFMS
HHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
VGLVGVIGACCLGYLLGQMIIPS
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]