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The map label for this gene is ltaE [H]

Identifier: 156976891

GI number: 156976891

Start: 877699

End: 878703

Strand: Reverse

Name: ltaE [H]

Synonym: VIBHAR_05668

Alternate gene names: 156976891

Gene position: 878703-877699 (Counterclockwise)

Preceding gene: 156976892

Following gene: 156976890

Centisome position: 39.87

GC content: 46.37

Gene sequence:

>1005_bases
ATGGACTTTCGATCAGATACTGTTACGCAACCTACCCAAGCCATGCGTGAAGCCATGTTTAACGCGCCTGTCGGAGACGA
TGTTTACGGTGACGACCCAAGCGTTAACGAGTTAGAACAATTTGCTGCTGAGCTCGCTGGGTTTGAAGCTGCGTTATTCA
CTTCATCTGGCACGCAGGCAAACCTACTTGGGTTAATGGCACATTGCGAACGCGGTGATGAATACCTGTGTGGCCAGCAA
GCACACAACTATAAATACGAAGCTGGTGGTGCTGCGGTACTGGGCTCTATTCAGCCTCAACCGATTGAAAACAACCCAGA
CGGCACTTTGCCATTTGATAAACTAGAAGCCGCGATTAAACCTGATGATGCGCACTTTGCACGTACTCGACTACTTAGCC
TAGAGAACACCATCAACGGTAAAGTGATTCCTCTCTCTTACCTTGCACAAGCACGTGAGTTCGTGAACAAGCACAATTTG
CAGATGCACCTAGATGGCGCTCGTGTATTCAACGCAGCCGTTGCACTTGATGTTCCGGTTAAAGAGATTGGTCAATACTT
TGATTCAATGACAATCTGTCTGTCGAAAGGGCTCGCTGCTCCTATTGGCTCATTATTACTGGGTAATAAAGAATACATCG
CTAAAGCGCGTCGCTTGAGAAAGATGGTCGGCGGAGGCATGCGTCAAGCGGGTATTCTTGCTGCAGCTGGTAAACTAGCC
CTTACCGAGCAAGTGGAACAACTAAAACAAGACCACATCAATGCAAAGACATTAGCGGAAGGTTTAGCGGAATTGCCTGG
TTTCTCTGTTAATCCAGAATTTGTTCAAACCAACATCGTTTTTGCCAAACTTGATCCACAAGTGGATATCGCTGGTATTG
CAGAAAAGATGAAAGAGCAAGGCATCACGATTACTCCAGGAAACCCAATCCGCTTCGTGACGCATAAAGATATTTCGGCA
CAAGACATCGATACTTTCCTATCTAGCCTTAAATCTATGCTTTAA

Upstream 100 bases:

>100_bases
AATTATTCAAGGCACCATCACTGATGCCAAAACCATCGCTTGCCTGAGCAAAGCTCGTCTTTGCGGTTATATTTAGGTCT
TTTTGACCGAGGAGAGAATT

Downstream 100 bases:

>100_bases
CTTGATTTTGATCATTGAGCTTCCCCTAAGGGGAAGCTTTATTCTATCTCGAAACCAATATTTTAAATTCGAGAACTATC
CATGCTTAGATACGTGCTTC

Product: L-allo-threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDFRSDTVTQPTQAMREAMFNAPVGDDVYGDDPSVNELEQFAAELAGFEAALFTSSGTQANLLGLMAHCERGDEYLCGQQ
AHNYKYEAGGAAVLGSIQPQPIENNPDGTLPFDKLEAAIKPDDAHFARTRLLSLENTINGKVIPLSYLAQAREFVNKHNL
QMHLDGARVFNAAVALDVPVKEIGQYFDSMTICLSKGLAAPIGSLLLGNKEYIAKARRLRKMVGGGMRQAGILAAAGKLA
LTEQVEQLKQDHINAKTLAEGLAELPGFSVNPEFVQTNIVFAKLDPQVDIAGIAEKMKEQGITITPGNPIRFVTHKDISA
QDIDTFLSSLKSML

Sequences:

>Translated_334_residues
MDFRSDTVTQPTQAMREAMFNAPVGDDVYGDDPSVNELEQFAAELAGFEAALFTSSGTQANLLGLMAHCERGDEYLCGQQ
AHNYKYEAGGAAVLGSIQPQPIENNPDGTLPFDKLEAAIKPDDAHFARTRLLSLENTINGKVIPLSYLAQAREFVNKHNL
QMHLDGARVFNAAVALDVPVKEIGQYFDSMTICLSKGLAAPIGSLLLGNKEYIAKARRLRKMVGGGMRQAGILAAAGKLA
LTEQVEQLKQDHINAKTLAEGLAELPGFSVNPEFVQTNIVFAKLDPQVDIAGIAEKMKEQGITITPGNPIRFVTHKDISA
QDIDTFLSSLKSML
>Mature_334_residues
MDFRSDTVTQPTQAMREAMFNAPVGDDVYGDDPSVNELEQFAAELAGFEAALFTSSGTQANLLGLMAHCERGDEYLCGQQ
AHNYKYEAGGAAVLGSIQPQPIENNPDGTLPFDKLEAAIKPDDAHFARTRLLSLENTINGKVIPLSYLAQAREFVNKHNL
QMHLDGARVFNAAVALDVPVKEIGQYFDSMTICLSKGLAAPIGSLLLGNKEYIAKARRLRKMVGGGMRQAGILAAAGKLA
LTEQVEQLKQDHINAKTLAEGLAELPGFSVNPEFVQTNIVFAKLDPQVDIAGIAEKMKEQGITITPGNPIRFVTHKDISA
QDIDTFLSSLKSML

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=334, Percent_Identity=56.8862275449102, Blast_Score=386, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI193206520, Length=353, Percent_Identity=38.8101983002833, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI193206522, Length=353, Percent_Identity=38.8101983002833, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI193206524, Length=353, Percent_Identity=38.8101983002833, Blast_Score=245, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6320789, Length=297, Percent_Identity=40.4040404040404, Blast_Score=208, Evalue=1e-54,
Organism=Drosophila melanogaster, GI21355439, Length=297, Percent_Identity=47.4747474747475, Blast_Score=263, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36161; Mature: 36161

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRSDTVTQPTQAMREAMFNAPVGDDVYGDDPSVNELEQFAAELAGFEAALFTSSGTQA
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEECCCCHH
NLLGLMAHCERGDEYLCGQQAHNYKYEAGGAAVLGSIQPQPIENNPDGTLPFDKLEAAIK
HHHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHCC
PDDAHFARTRLLSLENTINGKVIPLSYLAQAREFVNKHNLQMHLDGARVFNAAVALDVPV
CCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHEECCCH
KEIGQYFDSMTICLSKGLAAPIGSLLLGNKEYIAKARRLRKMVGGGMRQAGILAAAGKLA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHH
LTEQVEQLKQDHINAKTLAEGLAELPGFSVNPEFVQTNIVFAKLDPQVDIAGIAEKMKEQ
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHEEEEEEEEEECCCCCHHHHHHHHHHC
GITITPGNPIRFVTHKDISAQDIDTFLSSLKSML
CCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDFRSDTVTQPTQAMREAMFNAPVGDDVYGDDPSVNELEQFAAELAGFEAALFTSSGTQA
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEECCCCHH
NLLGLMAHCERGDEYLCGQQAHNYKYEAGGAAVLGSIQPQPIENNPDGTLPFDKLEAAIK
HHHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHCC
PDDAHFARTRLLSLENTINGKVIPLSYLAQAREFVNKHNLQMHLDGARVFNAAVALDVPV
CCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHEECCCH
KEIGQYFDSMTICLSKGLAAPIGSLLLGNKEYIAKARRLRKMVGGGMRQAGILAAAGKLA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHH
LTEQVEQLKQDHINAKTLAEGLAELPGFSVNPEFVQTNIVFAKLDPQVDIAGIAEKMKEQ
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHEEEEEEEEEECCCCCHHHHHHHHHHC
GITITPGNPIRFVTHKDISAQDIDTFLSSLKSML
CCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]