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The map label for this gene is aspA [H]

Identifier: 156976800

GI number: 156976800

Start: 777740

End: 779518

Strand: Reverse

Name: aspA [H]

Synonym: VIBHAR_05576

Alternate gene names: 156976800

Gene position: 779518-777740 (Counterclockwise)

Preceding gene: 156976801

Following gene: 156976799

Centisome position: 35.37

GC content: 48.57

Gene sequence:

>1779_bases
ATGGAAACACGCATTAATCGCCTATTCGCTGCAATGTTAGCAGTAGGCCTTTCTCCTGCCGTCTCGGCTTATGATCCGCT
CTACTCAGAGCAATGGCACCTAGACAACACAGGCCAAACTGCATTTGCAGCAAATCCTGCCGTTACGGGTAATGACTTGA
ACACCAAACTAACACAAGCGATGGGCATTGCTGGTGTTGGTGTAAAAGTTGCCGTTATTGACTCTGGCGTACAGATCGAT
CACCCAGACCTTGCAGGTAACGTAGTCACAGGTAGTAGAAACTTCGTTGAAGACTCTTCATTCCCAGCCGATTACCCAGT
TGATACAAATGGCCACGGTACCGCTGTTGCTGGCCTAATCAGTGCGGTTGGTAATAACGGTGAAGGCGTTCGCGGCGTAG
CTTCTCGCTCTTCTCTAATGGGCTTTAACTGGCTCGCAAACCAAACGCTGGAAGGCTGGTTGATTTCTCACGGCATGGAC
GCTGCAACCAGCGATGTTCGCGTTTTCAACCAAAGTTATGGTTTTAGCCCAATCTACCCTATTCCATTCGACGAGAACGA
CCCGCAGTTCAAGCTCGAAATGGATGTAATGAAAGACGTCAGCGAGCGTAATGCTTGGGGTCGTGGTGCTGTCTTCGTTA
AATCTGCTGGTAATGGTTACCGCTACTTCAACACTGGCCGTTTCTTCGTGCTTCCTAGCGACTTCTTCGCAGGCGGTGGC
AACAAAGGCCTACCAATGCATAACGCAGCACAGTCTTACGACAATGCGAGTTACTATAACCTTGTAACCAGCGCACTTCG
TGCTGACGGAACTCGTGCAAGCTACTCATCCGTTGGTGCTAACGTGTGGGTCGCAGCACCAGCAGGTGAATACGGTCAAG
ACTTCCCAGCAATGGTCACGACAGACTTAGTAGGCTGTGAAGAAGGTCAAAACACCAGTGCAGATTTAGGTATTAACGGC
CTTCACGGCGGTACTGAGCAAGATCCGAACTGTAACTACACCAGCACAATGAATGGTACGTCTTCAGCGGCGCCAAACAC
CTCTGGTGCAATTGCGGCGATTATGTCAACCAACCATGCGCTGACCGCTCGTGATGTCCGTGCGTTACTAGCAGAAACAG
CAAGCGTAACCGACAAAGACCACTCAGGTGTTCAACTTGAGTTCGTTAATAGCCAAGGAGACTTGGTCAGCTACGAAGCG
ATTTCACCATGGCAGACAAACGCAGCTGGCGTTGACTTCCATACCTTCTATGGTTTTGGCGCAGTTAACCTAGATGAAGC
GATGAAACGTGCTCGTATGACAAACAATGTTCTACCTGCACAAGTTATTACACCTTGGGCAAGCAATGCGACGGAAGTGA
GTGTTCCAGACGCAAGCTTGGCGGGTGGTTCTTCAGCGATTGCTATTACCGATGACATTACTGTTGAGTCAGTACAAGTG
AAACTTACACTTGAACACTCGCGTCTACCAGATTTGGCAATTGAGCTGATTTCTCCATCAGGTACACGTTCAGTTCTGCA
AACACCGCGTAATGGTCTCGTTGGTCAATCTCTTGATCCAACAGTAGCGGGTTATGAAAACCAGTTGATGCTTTCTAACC
AATTCTACGGTGAAAACGCGAAAGGCGAATGGACACTACGAGCGATCGATACCAACGGCGATGAAGTGTTCTCATTCATT
GCATATTTCAATTCTTCAGCTATCTATGATGTACCGATGGCTAACAACGCAAAACCAGGTGTTATCAAAAACTGGTCTAT
GCGTATCTTCGGTCACTAA

Upstream 100 bases:

>100_bases
ACAGTTTTCGTTTCCATTCTAAGCCGCTAGCTTTGTTTAGACCTGTTTAAAGGAGTATCGAACAGGGACAAAAATTCCAA
ACAAAGACATGAGGTCACAA

Downstream 100 bases:

>100_bases
GGAGTCATTCACATGAAATTTATGACATTTTCTATTCTGGCTCTATCGACAATGGCAGCGGCTGTACAAGCAGAGCAACA
ATTGGCTCAGCAACCTACAC

Product: serine proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
METRINRLFAAMLAVGLSPAVSAYDPLYSEQWHLDNTGQTAFAANPAVTGNDLNTKLTQAMGIAGVGVKVAVIDSGVQID
HPDLAGNVVTGSRNFVEDSSFPADYPVDTNGHGTAVAGLISAVGNNGEGVRGVASRSSLMGFNWLANQTLEGWLISHGMD
AATSDVRVFNQSYGFSPIYPIPFDENDPQFKLEMDVMKDVSERNAWGRGAVFVKSAGNGYRYFNTGRFFVLPSDFFAGGG
NKGLPMHNAAQSYDNASYYNLVTSALRADGTRASYSSVGANVWVAAPAGEYGQDFPAMVTTDLVGCEEGQNTSADLGING
LHGGTEQDPNCNYTSTMNGTSSAAPNTSGAIAAIMSTNHALTARDVRALLAETASVTDKDHSGVQLEFVNSQGDLVSYEA
ISPWQTNAAGVDFHTFYGFGAVNLDEAMKRARMTNNVLPAQVITPWASNATEVSVPDASLAGGSSAIAITDDITVESVQV
KLTLEHSRLPDLAIELISPSGTRSVLQTPRNGLVGQSLDPTVAGYENQLMLSNQFYGENAKGEWTLRAIDTNGDEVFSFI
AYFNSSAIYDVPMANNAKPGVIKNWSMRIFGH

Sequences:

>Translated_592_residues
METRINRLFAAMLAVGLSPAVSAYDPLYSEQWHLDNTGQTAFAANPAVTGNDLNTKLTQAMGIAGVGVKVAVIDSGVQID
HPDLAGNVVTGSRNFVEDSSFPADYPVDTNGHGTAVAGLISAVGNNGEGVRGVASRSSLMGFNWLANQTLEGWLISHGMD
AATSDVRVFNQSYGFSPIYPIPFDENDPQFKLEMDVMKDVSERNAWGRGAVFVKSAGNGYRYFNTGRFFVLPSDFFAGGG
NKGLPMHNAAQSYDNASYYNLVTSALRADGTRASYSSVGANVWVAAPAGEYGQDFPAMVTTDLVGCEEGQNTSADLGING
LHGGTEQDPNCNYTSTMNGTSSAAPNTSGAIAAIMSTNHALTARDVRALLAETASVTDKDHSGVQLEFVNSQGDLVSYEA
ISPWQTNAAGVDFHTFYGFGAVNLDEAMKRARMTNNVLPAQVITPWASNATEVSVPDASLAGGSSAIAITDDITVESVQV
KLTLEHSRLPDLAIELISPSGTRSVLQTPRNGLVGQSLDPTVAGYENQLMLSNQFYGENAKGEWTLRAIDTNGDEVFSFI
AYFNSSAIYDVPMANNAKPGVIKNWSMRIFGH
>Mature_592_residues
METRINRLFAAMLAVGLSPAVSAYDPLYSEQWHLDNTGQTAFAANPAVTGNDLNTKLTQAMGIAGVGVKVAVIDSGVQID
HPDLAGNVVTGSRNFVEDSSFPADYPVDTNGHGTAVAGLISAVGNNGEGVRGVASRSSLMGFNWLANQTLEGWLISHGMD
AATSDVRVFNQSYGFSPIYPIPFDENDPQFKLEMDVMKDVSERNAWGRGAVFVKSAGNGYRYFNTGRFFVLPSDFFAGGG
NKGLPMHNAAQSYDNASYYNLVTSALRADGTRASYSSVGANVWVAAPAGEYGQDFPAMVTTDLVGCEEGQNTSADLGING
LHGGTEQDPNCNYTSTMNGTSSAAPNTSGAIAAIMSTNHALTARDVRALLAETASVTDKDHSGVQLEFVNSQGDLVSYEA
ISPWQTNAAGVDFHTFYGFGAVNLDEAMKRARMTNNVLPAQVITPWASNATEVSVPDASLAGGSSAIAITDDITVESVQV
KLTLEHSRLPDLAIELISPSGTRSVLQTPRNGLVGQSLDPTVAGYENQLMLSNQFYGENAKGEWTLRAIDTNGDEVFSFI
AYFNSSAIYDVPMANNAKPGVIKNWSMRIFGH

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI20336244, Length=587, Percent_Identity=24.3611584327087, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI76443679, Length=557, Percent_Identity=26.2118491921005, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI299523015, Length=594, Percent_Identity=23.9057239057239, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI20336180, Length=590, Percent_Identity=25.2542372881356, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4505577, Length=590, Percent_Identity=25.2542372881356, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI20336184, Length=590, Percent_Identity=25.2542372881356, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI20336182, Length=590, Percent_Identity=25.2542372881356, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI4505579, Length=549, Percent_Identity=24.7723132969035, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI20336246, Length=592, Percent_Identity=23.9864864864865, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI27894285, Length=547, Percent_Identity=25.2285191956124, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI20336190, Length=547, Percent_Identity=25.2285191956124, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI20336188, Length=547, Percent_Identity=25.2285191956124, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI295424143, Length=555, Percent_Identity=26.3063063063063, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI20336242, Length=557, Percent_Identity=26.2118491921005, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI20336248, Length=584, Percent_Identity=25, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI295424145, Length=241, Percent_Identity=28.6307053941909, Blast_Score=74, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71987206, Length=575, Percent_Identity=26.6086956521739, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71988321, Length=549, Percent_Identity=25.8652094717668, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71988301, Length=549, Percent_Identity=25.8652094717668, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988308, Length=547, Percent_Identity=25.5941499085923, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988312, Length=547, Percent_Identity=25.5941499085923, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988315, Length=549, Percent_Identity=25.8652094717668, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988297, Length=549, Percent_Identity=25.8652094717668, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25141268, Length=551, Percent_Identity=24.5009074410163, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71987215, Length=483, Percent_Identity=25.0517598343685, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71983555, Length=426, Percent_Identity=23.7089201877934, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324091, Length=569, Percent_Identity=23.5500878734622, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17136192, Length=543, Percent_Identity=25.0460405156538, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24642494, Length=582, Percent_Identity=25.085910652921, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642490, Length=582, Percent_Identity=25.085910652921, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45555723, Length=582, Percent_Identity=25.085910652921, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642492, Length=582, Percent_Identity=25.085910652921, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360987, Length=582, Percent_Identity=25.085910652921, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642488, Length=584, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642484, Length=584, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642486, Length=584, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24650058, Length=559, Percent_Identity=23.4347048300537, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24650060, Length=559, Percent_Identity=23.4347048300537, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45553513, Length=559, Percent_Identity=23.4347048300537, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45553515, Length=559, Percent_Identity=23.4347048300537, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17864552, Length=559, Percent_Identity=23.4347048300537, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24650056, Length=559, Percent_Identity=23.4347048300537, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 62912; Mature: 62912

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRINRLFAAMLAVGLSPAVSAYDPLYSEQWHLDNTGQTAFAANPAVTGNDLNTKLTQA
CCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHH
MGIAGVGVKVAVIDSGVQIDHPDLAGNVVTGSRNFVEDSSFPADYPVDTNGHGTAVAGLI
HCCCCCCEEEEEEECCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
SAVGNNGEGVRGVASRSSLMGFNWLANQTLEGWLISHGMDAATSDVRVFNQSYGFSPIYP
HHHCCCCCCCEEHHHHCHHCCCHHHHCCCCCCCCEECCCCCCCCHHEEEHHCCCCCCCCC
IPFDENDPQFKLEMDVMKDVSERNAWGRGAVFVKSAGNGYRYFNTGRFFVLPSDFFAGGG
CCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCEEEEECCHHHCCCC
NKGLPMHNAAQSYDNASYYNLVTSALRADGTRASYSSVGANVWVAAPAGEYGQDFPAMVT
CCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHH
TDLVGCEEGQNTSADLGINGLHGGTEQDPNCNYTSTMNGTSSAAPNTSGAIAAIMSTNHA
HHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCC
LTARDVRALLAETASVTDKDHSGVQLEFVNSQGDLVSYEAISPWQTNAAGVDFHTFYGFG
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEHHHHCCC
AVNLDEAMKRARMTNNVLPAQVITPWASNATEVSVPDASLAGGSSAIAITDDITVESVQV
CCCHHHHHHHHHHHCCCCCHHEECCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEEEE
KLTLEHSRLPDLAIELISPSGTRSVLQTPRNGLVGQSLDPTVAGYENQLMLSNQFYGENA
EEEECCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
KGEWTLRAIDTNGDEVFSFIAYFNSSAIYDVPMANNAKPGVIKNWSMRIFGH
CCCEEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCEEEECC
>Mature Secondary Structure
METRINRLFAAMLAVGLSPAVSAYDPLYSEQWHLDNTGQTAFAANPAVTGNDLNTKLTQA
CCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHH
MGIAGVGVKVAVIDSGVQIDHPDLAGNVVTGSRNFVEDSSFPADYPVDTNGHGTAVAGLI
HCCCCCCEEEEEEECCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
SAVGNNGEGVRGVASRSSLMGFNWLANQTLEGWLISHGMDAATSDVRVFNQSYGFSPIYP
HHHCCCCCCCEEHHHHCHHCCCHHHHCCCCCCCCEECCCCCCCCHHEEEHHCCCCCCCCC
IPFDENDPQFKLEMDVMKDVSERNAWGRGAVFVKSAGNGYRYFNTGRFFVLPSDFFAGGG
CCCCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCEEEEECCHHHCCCC
NKGLPMHNAAQSYDNASYYNLVTSALRADGTRASYSSVGANVWVAAPAGEYGQDFPAMVT
CCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHH
TDLVGCEEGQNTSADLGINGLHGGTEQDPNCNYTSTMNGTSSAAPNTSGAIAAIMSTNHA
HHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCC
LTARDVRALLAETASVTDKDHSGVQLEFVNSQGDLVSYEAISPWQTNAAGVDFHTFYGFG
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEHHHHCCC
AVNLDEAMKRARMTNNVLPAQVITPWASNATEVSVPDASLAGGSSAIAITDDITVESVQV
CCCHHHHHHHHHHHCCCCCHHEECCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEEEE
KLTLEHSRLPDLAIELISPSGTRSVLQTPRNGLVGQSLDPTVAGYENQLMLSNQFYGENA
EEEECCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
KGEWTLRAIDTNGDEVFSFIAYFNSSAIYDVPMANNAKPGVIKNWSMRIFGH
CCCEEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]