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The map label for this gene is yhcK [H]

Identifier: 156976625

GI number: 156976625

Start: 621976

End: 623418

Strand: Direct

Name: yhcK [H]

Synonym: VIBHAR_05399

Alternate gene names: 156976625

Gene position: 621976-623418 (Clockwise)

Preceding gene: 156976623

Following gene: 156976626

Centisome position: 28.22

GC content: 45.18

Gene sequence:

>1443_bases
ATGACTCTCATACGTTATAGTACTTATGTTTGGAAAAACACCACGTTTAGCATTGCTCTATTAATAGTGGGCGTGCTGCA
TAGTGCTGTGACGTATGGTCAAGAGACCCAGAAAGAGACTCTCGTTATCGCTAATTCAAAAGCGTGGAAGCCTTTCTCTT
ATCTCACACCAGATGGTGAGCCTAAAGGCATCTTAATTGATTTTTGGCGTGAGTATGCCGTTAGAAATGATGTTCATGTT
CAGTTTCTTCTGCTTGATTGGGAAGACTCTTTGCTCGCAGTGAAAGAAGGTAGAGCAGACATTCATGCTGGGCTCATATT
TTCAGAAGAGCGCAACCAGTACCTGAACTTTGGCACAGTGATCATGCCTATTGATACCCAACTATACGTGAACAGCGACC
TTTTGGGCATCGATGTTGATTCGGTGTTGGCTGGGGAGTCTGCGATGGAGGTGGGGTTAGTTAAAGGGGGATATGAAGAG
ACTTTCGTTCGTAAGCGTTATCCCAATGCCGCAATAAAACGGTTTGCGAATAGTGATGCATTATTAAAAGCCGTTACCGA
CAAAAAGATATTCCTGTTTGTGGTCGATACTCAAGTGTCTAATTTCTATATGGCGACGACATCAGATGCAGTGACGTTCT
TGCCTGCATTACACCTTTATAGCAAAAGCTTGAGAATCGCGACGGGAGAGGCGAGCTCAGAGTCGATCGAAGCCATCTCC
AAGAAATTTGAAACGGTGTTGGAAGCAGACAAAGATCGAATTTTAAGTCGTTGGATCCACGTTAAAACGGTTTATCCCGC
CTATTTGGCGCCCCTTGCTGTGTTTGCTCTTATTATGGCGGCTATGTTCCATATCTTTTCACTCAAACGCACGGTGGCGC
TGCGCGCGCGGCAACTCACTATGGCGAATCAACAGCTTTTTGAGCTCACCCTGACTGACCCTCTCACTAAGCTTTATAAT
CGACGTCACTTGATTGAGCGTTTAGCGACGTTAAGTAACGTAAGGCGAAACTTGACCGTGATGGTGTTTGATATTGATGA
CTTCAAATCCATCAATGACCAATTCGGGCATGTGGTTGGCGATCAAGCCATTATCGCCGTTGCGAATACGGCGAGAACCG
TGATCGATGAAAGAATGACGTTGGCACGCATTGGTGGTGAAGAGTTCGCTTTGGTGACAGCTTCGCTTTCTGCTGAAGAA
GCTGAAGTACTCGCTCGTACAATTTGCACCCAAGTGCATTGCTCACCGGTGACTTTGGATGGACAAACGATTAGCGTGAG
TATCAGTTTAGGGTGCGCGTATTATCCAAAATTTGATGAACAACCAAGCCTGCAAGATGCAGATCAACTTATGTACCGTG
GCAAGGCAAATGGGAAAAATCGTGCAGTGTTCCAAATCATTAACAGAAACAAAGTTGAGCCATTACTTCTTAAAGCTCAG
TGA

Upstream 100 bases:

>100_bases
TATCAATAAGAGTCTCTTCCCATATCTAAAAGCTCTGCTGTATCTTTAGTTCGATTTAAGTCTTAGATAACTCTTTCGGA
CAGGGTGGCGAGAAGTAGGA

Downstream 100 bases:

>100_bases
AACTTTGAGCGAGCTCTCGCTGACCTCTATTCTCTTCTTGCTATACTGATCTGAACTCTCTGTTTTTATTGTTATTTCTG
ATGCTAATCGTGTCGGGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTLIRYSTYVWKNTTFSIALLIVGVLHSAVTYGQETQKETLVIANSKAWKPFSYLTPDGEPKGILIDFWREYAVRNDVHV
QFLLLDWEDSLLAVKEGRADIHAGLIFSEERNQYLNFGTVIMPIDTQLYVNSDLLGIDVDSVLAGESAMEVGLVKGGYEE
TFVRKRYPNAAIKRFANSDALLKAVTDKKIFLFVVDTQVSNFYMATTSDAVTFLPALHLYSKSLRIATGEASSESIEAIS
KKFETVLEADKDRILSRWIHVKTVYPAYLAPLAVFALIMAAMFHIFSLKRTVALRARQLTMANQQLFELTLTDPLTKLYN
RRHLIERLATLSNVRRNLTVMVFDIDDFKSINDQFGHVVGDQAIIAVANTARTVIDERMTLARIGGEEFALVTASLSAEE
AEVLARTICTQVHCSPVTLDGQTISVSISLGCAYYPKFDEQPSLQDADQLMYRGKANGKNRAVFQIINRNKVEPLLLKAQ

Sequences:

>Translated_480_residues
MTLIRYSTYVWKNTTFSIALLIVGVLHSAVTYGQETQKETLVIANSKAWKPFSYLTPDGEPKGILIDFWREYAVRNDVHV
QFLLLDWEDSLLAVKEGRADIHAGLIFSEERNQYLNFGTVIMPIDTQLYVNSDLLGIDVDSVLAGESAMEVGLVKGGYEE
TFVRKRYPNAAIKRFANSDALLKAVTDKKIFLFVVDTQVSNFYMATTSDAVTFLPALHLYSKSLRIATGEASSESIEAIS
KKFETVLEADKDRILSRWIHVKTVYPAYLAPLAVFALIMAAMFHIFSLKRTVALRARQLTMANQQLFELTLTDPLTKLYN
RRHLIERLATLSNVRRNLTVMVFDIDDFKSINDQFGHVVGDQAIIAVANTARTVIDERMTLARIGGEEFALVTASLSAEE
AEVLARTICTQVHCSPVTLDGQTISVSISLGCAYYPKFDEQPSLQDADQLMYRGKANGKNRAVFQIINRNKVEPLLLKAQ
>Mature_479_residues
TLIRYSTYVWKNTTFSIALLIVGVLHSAVTYGQETQKETLVIANSKAWKPFSYLTPDGEPKGILIDFWREYAVRNDVHVQ
FLLLDWEDSLLAVKEGRADIHAGLIFSEERNQYLNFGTVIMPIDTQLYVNSDLLGIDVDSVLAGESAMEVGLVKGGYEET
FVRKRYPNAAIKRFANSDALLKAVTDKKIFLFVVDTQVSNFYMATTSDAVTFLPALHLYSKSLRIATGEASSESIEAISK
KFETVLEADKDRILSRWIHVKTVYPAYLAPLAVFALIMAAMFHIFSLKRTVALRARQLTMANQQLFELTLTDPLTKLYNR
RHLIERLATLSNVRRNLTVMVFDIDDFKSINDQFGHVVGDQAIIAVANTARTVIDERMTLARIGGEEFALVTASLSAEEA
EVLARTICTQVHCSPVTLDGQTISVSISLGCAYYPKFDEQPSLQDADQLMYRGKANGKNRAVFQIINRNKVEPLLLKAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787802, Length=184, Percent_Identity=34.2391304347826, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=33.7142857142857, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787262, Length=215, Percent_Identity=28.3720930232558, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=166, Percent_Identity=34.3373493975904, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788956, Length=188, Percent_Identity=34.0425531914894, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=110, Percent_Identity=40, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787541, Length=164, Percent_Identity=29.8780487804878, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=166, Percent_Identity=28.3132530120482, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081881, Length=212, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788381, Length=155, Percent_Identity=28.3870967741935, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 53846; Mature: 53714

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIRYSTYVWKNTTFSIALLIVGVLHSAVTYGQETQKETLVIANSKAWKPFSYLTPDGE
CEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PKGILIDFWREYAVRNDVHVQFLLLDWEDSLLAVKEGRADIHAGLIFSEERNQYLNFGTV
CCEEEHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEECCCEE
IMPIDTQLYVNSDLLGIDVDSVLAGESAMEVGLVKGGYEETFVRKRYPNAAIKRFANSDA
EEEECCEEEECCCEEECCHHHHHCCCCHHEEEEECCCHHHHHHHHCCCCHHHHHHCCCCH
LLKAVTDKKIFLFVVDTQVSNFYMATTSDAVTFLPALHLYSKSLRIATGEASSESIEAIS
HEEEECCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
KKFETVLEADKDRILSRWIHVKTVYPAYLAPLAVFALIMAAMFHIFSLKRTVALRARQLT
HHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MANQQLFELTLTDPLTKLYNRRHLIERLATLSNVRRNLTVMVFDIDDFKSINDQFGHVVG
HCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCC
DQAIIAVANTARTVIDERMTLARIGGEEFALVTASLSAEEAEVLARTICTQVHCSPVTLD
CCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEC
GQTISVSISLGCAYYPKFDEQPSLQDADQLMYRGKANGKNRAVFQIINRNKVEPLLLKAQ
CCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECC
>Mature Secondary Structure 
TLIRYSTYVWKNTTFSIALLIVGVLHSAVTYGQETQKETLVIANSKAWKPFSYLTPDGE
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PKGILIDFWREYAVRNDVHVQFLLLDWEDSLLAVKEGRADIHAGLIFSEERNQYLNFGTV
CCEEEHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEECCCEE
IMPIDTQLYVNSDLLGIDVDSVLAGESAMEVGLVKGGYEETFVRKRYPNAAIKRFANSDA
EEEECCEEEECCCEEECCHHHHHCCCCHHEEEEECCCHHHHHHHHCCCCHHHHHHCCCCH
LLKAVTDKKIFLFVVDTQVSNFYMATTSDAVTFLPALHLYSKSLRIATGEASSESIEAIS
HEEEECCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
KKFETVLEADKDRILSRWIHVKTVYPAYLAPLAVFALIMAAMFHIFSLKRTVALRARQLT
HHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MANQQLFELTLTDPLTKLYNRRHLIERLATLSNVRRNLTVMVFDIDDFKSINDQFGHVVG
HCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCC
DQAIIAVANTARTVIDERMTLARIGGEEFALVTASLSAEEAEVLARTICTQVHCSPVTLD
CCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEC
GQTISVSISLGCAYYPKFDEQPSLQDADQLMYRGKANGKNRAVFQIINRNKVEPLLLKAQ
CCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]