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The map label for this gene is 156976611

Identifier: 156976611

GI number: 156976611

Start: 611903

End: 612409

Strand: Reverse

Name: 156976611

Synonym: VIBHAR_05385

Alternate gene names: NA

Gene position: 612409-611903 (Counterclockwise)

Preceding gene: 156976613

Following gene: 156976608

Centisome position: 27.79

GC content: 44.97

Gene sequence:

>507_bases
ATGCGTTATCATGCAGACAATTCAAAGCTTTCGACCGAGAGGATGAGTATGATTTCTAAATGGGAGAAACGGTTCTACCA
GATGGCTGAACTTGTTGCGTCATGGAGTAAAGATCCATCCACACAAGTTGGCGCGGTAATCACCAAAAATAACCGCATTG
TTTCTGTTGGCTTCAACGGCTACCCACACGGCGTATCTGACAGCGTTGATACAGATGAACGCGAACTGAAATATCTAAAA
ACGCTTCACGCAGAAGAGAACGCCATTTTGTTTTCGAAGCGTGACTTAGATGGTTGTGATATTTGGGTAACCCACTTCCC
TTGCCCGAACTGTGCAGCAAAAATCATTCAAACAGGGATTGCACGTGTAAGCTGCCCTGAACAATCTGAAGATTTCTTAT
CTCGCTGGGGCGACAAGATTAAAGTGAGCCAAGACATGTTCGACCAAGCGGGTGTTGAAGTAAACTGGCTACCAATCAAC
GAGATCGAAGAGAAAAGCGTTCGTTAA

Upstream 100 bases:

>100_bases
GTGAAAACATACCGATAAATTAGACAATAATTCATCAGCTTCACGTAAAAATCGACACTTCATAATTACCGTGAGTGTTT
TGACTATTTTTTTAAACTGA

Downstream 100 bases:

>100_bases
GACGTTACTCAGCTTTTGTGTAAATGTTCAGACAATCTAAACGTTTGCCAAAACCAACCAAAAAGCCCAGACAGTCGTCT
GGGCTTTTGTTTTTCTCTGT

Product: deoxycytidylate deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRYHADNSKLSTERMSMISKWEKRFYQMAELVASWSKDPSTQVGAVITKNNRIVSVGFNGYPHGVSDSVDTDERELKYLK
TLHAEENAILFSKRDLDGCDIWVTHFPCPNCAAKIIQTGIARVSCPEQSEDFLSRWGDKIKVSQDMFDQAGVEVNWLPIN
EIEEKSVR

Sequences:

>Translated_168_residues
MRYHADNSKLSTERMSMISKWEKRFYQMAELVASWSKDPSTQVGAVITKNNRIVSVGFNGYPHGVSDSVDTDERELKYLK
TLHAEENAILFSKRDLDGCDIWVTHFPCPNCAAKIIQTGIARVSCPEQSEDFLSRWGDKIKVSQDMFDQAGVEVNWLPIN
EIEEKSVR
>Mature_168_residues
MRYHADNSKLSTERMSMISKWEKRFYQMAELVASWSKDPSTQVGAVITKNNRIVSVGFNGYPHGVSDSVDTDERELKYLK
TLHAEENAILFSKRDLDGCDIWVTHFPCPNCAAKIIQTGIARVSCPEQSEDFLSRWGDKIKVSQDMFDQAGVEVNWLPIN
EIEEKSVR

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742821, Length=156, Percent_Identity=38.4615384615385, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI61742819, Length=156, Percent_Identity=38.4615384615385, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557019, Length=138, Percent_Identity=41.304347826087, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321938, Length=117, Percent_Identity=35.8974358974359, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667298, Length=149, Percent_Identity=39.5973154362416, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24667302, Length=149, Percent_Identity=39.5973154362416, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 19190; Mature: 19190

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYHADNSKLSTERMSMISKWEKRFYQMAELVASWSKDPSTQVGAVITKNNRIVSVGFNG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEECCCC
YPHGVSDSVDTDERELKYLKTLHAEENAILFSKRDLDGCDIWVTHFPCPNCAAKIIQTGI
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHH
ARVSCPEQSEDFLSRWGDKIKVSQDMFDQAGVEVNWLPINEIEEKSVR
HHCCCCCCHHHHHHHCCCEEEECHHHHHHCCCEEEEEECCCHHHCCCC
>Mature Secondary Structure
MRYHADNSKLSTERMSMISKWEKRFYQMAELVASWSKDPSTQVGAVITKNNRIVSVGFNG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEECCCC
YPHGVSDSVDTDERELKYLKTLHAEENAILFSKRDLDGCDIWVTHFPCPNCAAKIIQTGI
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHH
ARVSCPEQSEDFLSRWGDKIKVSQDMFDQAGVEVNWLPINEIEEKSVR
HHCCCCCCHHHHHHHCCCEEEECHHHHHHCCCEEEEEECCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]