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The map label for this gene is gap [H]

Identifier: 156976567

GI number: 156976567

Start: 572466

End: 573899

Strand: Reverse

Name: gap [H]

Synonym: VIBHAR_05341

Alternate gene names: 156976567

Gene position: 573899-572466 (Counterclockwise)

Preceding gene: 156976568

Following gene: 156976566

Centisome position: 26.04

GC content: 46.79

Gene sequence:

>1434_bases
ATGAGTCCAGAGAAATATCTCCAAGACTGGCAAACTAGCCAAACGATTGCTGAATCTATTTCCCCTCTTATTGGTAAGTT
ATATCGTCAAAAAGGAATCGAAGTGGTTCTGTTTGGTAAAACGCTTATCAACGCAACAACCATCGACATTCTCAAAACTC
ACCGTATTGCAAGACGTTACACAGGAAGCCCTCTCTCTCTAGAACAAACGATGCCAATAATCCAAGCGCTTTGCGAAATG
AGCATCTCGTCTTGCCGTGTTGATGTTGGTCAGCTTGCTGGTATGTACTGGAAAGATCACGAAGACACAGCCGCACTTAG
CGACTTTTTACACACTGCACTTCAAGGTGCTCGTGACGCCGATTCTTCTCTAGCGGCTCGTGATGTGGTTCTTTATGGTT
TCGGTCGAATTGGTCGTCTACTTACTCGTCTGCTGATTGAAAAGAGTGGTCCGGGTTACCCGCTTCGTCTGCGTGCTATC
GTGGTACGTGGTGGCAAGAAAGGTGATCTTGAGAAGCGTGCAAGCTTGCTACGTCGTGACTCCGTTCATGGACAGTTCAA
CGGTAGTATCGTGATTGATGAAGAGCGCAAAGCGCTGATTGTAAACGGTAACTACATTCAAATTATTTACGCCAACAGCC
CGAGCGATGTGGACTACTCAGTTTACGGTATCAACAATGCGCTAGTTGTTGATAACACGGGCGTTTGGCGCGATGCCGAA
GGTCTTAGCCAACACGTAGCGTGTAACGGTGCAGAGAAAGTATTGCTTACTGCACCAGGTAAAGGCGACATCAAGAACGT
CGTATTTGGTGTGAATGAATCTGTGATTCAAGAAGATGACACCATCATCTCCGCAGCGAGCTGTACGACTAACGCTATCA
CTCCGGTACTTAAAGCACTTAACGACAAGTACGGCGTGCTTTCTGGACACATTGAGACTGTTCACTCTTACACGAATGAT
CAAAACTTGATCGACAACTTCCACTCAGGCGATCGCCGTGGTCGTAGTGCTTCATTGAACATGGTTCTGACATCAACAGG
CGCAGCGAAAGCGGTAGCAAAAGCACTGCCAGAACTTGCTGGTAAACTTACAGGCAACGCAATTCGCGTACCAACTCCGA
ACGTATCAATGGCTGTTACAAACCTTAACTTGGGTGAAGATGTAGACCGTGATTCGCTGAACGAATACCTACGTCAAATG
GCATTGAATTCGGAGCTTTCCGCGCAAATCGATTACACAGATTCGACAGAAATCGTATCAAGCGATCTAGTTGGCTCTCG
CCACGCTGGTGTGGTTGACGGTCAAGCAACCATCGCTCAAGACAAGCGTTGTGTACTGTACATCTGGTACGACAACGAAT
TTGGTTACAGCTGTCAAGTTGTACACTGTATGGAACAAATGATGGGTGTTCGTTACCAAACATTCCCTCGATAA

Upstream 100 bases:

>100_bases
TACAACTTAATTACAAACACCCTCACTTCACGCTCTACCGTTGAGGTACTAGCCGAAAAGTAAGGTCAGCCCCCCAAAAC
GTGAAAGGTCCAAAACAACA

Downstream 100 bases:

>100_bases
GGTGAACCTTGCTCCACAACGTTAACCACAATGTGTAACGAGCAACACCCCAGCATTTGTTTTAAATAATAAGCGCCTTG
CGCATTACTAATATACTTCC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSPEKYLQDWQTSQTIAESISPLIGKLYRQKGIEVVLFGKTLINATTIDILKTHRIARRYTGSPLSLEQTMPIIQALCEM
SISSCRVDVGQLAGMYWKDHEDTAALSDFLHTALQGARDADSSLAARDVVLYGFGRIGRLLTRLLIEKSGPGYPLRLRAI
VVRGGKKGDLEKRASLLRRDSVHGQFNGSIVIDEERKALIVNGNYIQIIYANSPSDVDYSVYGINNALVVDNTGVWRDAE
GLSQHVACNGAEKVLLTAPGKGDIKNVVFGVNESVIQEDDTIISAASCTTNAITPVLKALNDKYGVLSGHIETVHSYTND
QNLIDNFHSGDRRGRSASLNMVLTSTGAAKAVAKALPELAGKLTGNAIRVPTPNVSMAVTNLNLGEDVDRDSLNEYLRQM
ALNSELSAQIDYTDSTEIVSSDLVGSRHAGVVDGQATIAQDKRCVLYIWYDNEFGYSCQVVHCMEQMMGVRYQTFPR

Sequences:

>Translated_477_residues
MSPEKYLQDWQTSQTIAESISPLIGKLYRQKGIEVVLFGKTLINATTIDILKTHRIARRYTGSPLSLEQTMPIIQALCEM
SISSCRVDVGQLAGMYWKDHEDTAALSDFLHTALQGARDADSSLAARDVVLYGFGRIGRLLTRLLIEKSGPGYPLRLRAI
VVRGGKKGDLEKRASLLRRDSVHGQFNGSIVIDEERKALIVNGNYIQIIYANSPSDVDYSVYGINNALVVDNTGVWRDAE
GLSQHVACNGAEKVLLTAPGKGDIKNVVFGVNESVIQEDDTIISAASCTTNAITPVLKALNDKYGVLSGHIETVHSYTND
QNLIDNFHSGDRRGRSASLNMVLTSTGAAKAVAKALPELAGKLTGNAIRVPTPNVSMAVTNLNLGEDVDRDSLNEYLRQM
ALNSELSAQIDYTDSTEIVSSDLVGSRHAGVVDGQATIAQDKRCVLYIWYDNEFGYSCQVVHCMEQMMGVRYQTFPR
>Mature_476_residues
SPEKYLQDWQTSQTIAESISPLIGKLYRQKGIEVVLFGKTLINATTIDILKTHRIARRYTGSPLSLEQTMPIIQALCEMS
ISSCRVDVGQLAGMYWKDHEDTAALSDFLHTALQGARDADSSLAARDVVLYGFGRIGRLLTRLLIEKSGPGYPLRLRAIV
VRGGKKGDLEKRASLLRRDSVHGQFNGSIVIDEERKALIVNGNYIQIIYANSPSDVDYSVYGINNALVVDNTGVWRDAEG
LSQHVACNGAEKVLLTAPGKGDIKNVVFGVNESVIQEDDTIISAASCTTNAITPVLKALNDKYGVLSGHIETVHSYTNDQ
NLIDNFHSGDRRGRSASLNMVLTSTGAAKAVAKALPELAGKLTGNAIRVPTPNVSMAVTNLNLGEDVDRDSLNEYLRQMA
LNSELSAQIDYTDSTEIVSSDLVGSRHAGVVDGQATIAQDKRCVLYIWYDNEFGYSCQVVHCMEQMMGVRYQTFPR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=35.693215339233, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=39.0532544378698, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1788079, Length=341, Percent_Identity=36.3636363636364, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789295, Length=347, Percent_Identity=32.8530259365994, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17534679, Length=345, Percent_Identity=35.6521739130435, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17534677, Length=345, Percent_Identity=35.3623188405797, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=36.0119047619048, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=36.0119047619048, Blast_Score=181, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=36.8731563421829, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322468, Length=341, Percent_Identity=36.0703812316716, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6321631, Length=341, Percent_Identity=36.0703812316716, Blast_Score=196, Evalue=6e-51,
Organism=Drosophila melanogaster, GI17933600, Length=338, Percent_Identity=37.8698224852071, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI18110149, Length=338, Percent_Identity=37.8698224852071, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI85725000, Length=338, Percent_Identity=37.5739644970414, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI22023983, Length=338, Percent_Identity=37.5739644970414, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=37.9518072289157, Blast_Score=190, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 52193; Mature: 52062

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00071 GAPDH ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEKYLQDWQTSQTIAESISPLIGKLYRQKGIEVVLFGKTLINATTIDILKTHRIARRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
TGSPLSLEQTMPIIQALCEMSISSCRVDVGQLAGMYWKDHEDTAALSDFLHTALQGARDA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC
DSSLAARDVVLYGFGRIGRLLTRLLIEKSGPGYPLRLRAIVVRGGKKGDLEKRASLLRRD
CCHHHHHHHHEECHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHH
SVHGQFNGSIVIDEERKALIVNGNYIQIIYANSPSDVDYSVYGINNALVVDNTGVWRDAE
CCCCEECCEEEEECCCCEEEEECCEEEEEECCCCCCCCEEEEECCCEEEEECCCCCCCHH
GLSQHVACNGAEKVLLTAPGKGDIKNVVFGVNESVIQEDDTIISAASCTTNAITPVLKAL
HHHHHHCCCCCCEEEEECCCCCCCCCEEECCCHHHHCCCCCEEEECCCCHHHHHHHHHHH
NDKYGVLSGHIETVHSYTNDQNLIDNFHSGDRRGRSASLNMVLTSTGAAKAVAKALPELA
CCCCCEEECHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
GKLTGNAIRVPTPNVSMAVTNLNLGEDVDRDSLNEYLRQMALNSELSAQIDYTDSTEIVS
HHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
SDLVGSRHAGVVDGQATIAQDKRCVLYIWYDNEFGYSCQVVHCMEQMMGVRYQTFPR
HHCCCCCCCCEECCCCEEECCCEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SPEKYLQDWQTSQTIAESISPLIGKLYRQKGIEVVLFGKTLINATTIDILKTHRIARRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
TGSPLSLEQTMPIIQALCEMSISSCRVDVGQLAGMYWKDHEDTAALSDFLHTALQGARDA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC
DSSLAARDVVLYGFGRIGRLLTRLLIEKSGPGYPLRLRAIVVRGGKKGDLEKRASLLRRD
CCHHHHHHHHEECHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHH
SVHGQFNGSIVIDEERKALIVNGNYIQIIYANSPSDVDYSVYGINNALVVDNTGVWRDAE
CCCCEECCEEEEECCCCEEEEECCEEEEEECCCCCCCCEEEEECCCEEEEECCCCCCCHH
GLSQHVACNGAEKVLLTAPGKGDIKNVVFGVNESVIQEDDTIISAASCTTNAITPVLKAL
HHHHHHCCCCCCEEEEECCCCCCCCCEEECCCHHHHCCCCCEEEECCCCHHHHHHHHHHH
NDKYGVLSGHIETVHSYTNDQNLIDNFHSGDRRGRSASLNMVLTSTGAAKAVAKALPELA
CCCCCEEECHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
GKLTGNAIRVPTPNVSMAVTNLNLGEDVDRDSLNEYLRQMALNSELSAQIDYTDSTEIVS
HHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
SDLVGSRHAGVVDGQATIAQDKRCVLYIWYDNEFGYSCQVVHCMEQMMGVRYQTFPR
HHCCCCCCCCEECCCCEEECCCEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8508805; 10360571; 2401296; 7877172 [H]