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The map label for this gene is codB [H]

Identifier: 156976547

GI number: 156976547

Start: 553513

End: 554751

Strand: Reverse

Name: codB [H]

Synonym: VIBHAR_05320

Alternate gene names: 156976547

Gene position: 554751-553513 (Counterclockwise)

Preceding gene: 156976549

Following gene: 156976546

Centisome position: 25.17

GC content: 47.86

Gene sequence:

>1239_bases
ATGGCTGCGGACAATAACTACAGTCTTGGACCGGTTCCTAACACTGCCAGAAAAGGCGTGGCATCATTAACCATGGTTAT
GTTGGGGCTCACTTTCTTCTCCGCAAGCATGTGGACGGGCGGCTCGCTCGGTACCGGACTTTCTTTTGATGATTTCTTCC
TCGCTGTTCTCATTGGTAACCTAATCCTCGGCATCTACACTTCTTTTCTTGGTTACATCGGCGCTTCTACTGGTCTCTCT
ACTCACCTCCTTGCTCGTTTCTCTTTTGGCTCTAAAGGCTCTTGGCTTCCTTCCGCTCTTCTTGGCGGCACACAAGTTGG
TTGGTTTGGTGTTGGCGTGGCGATGTTTGCTATTCCAGTAAACAAAGCAACAGGCATCGATACAAACACGCTTATCATCA
TTTCTGGTCTATTAATGACTGCGACGGTTTACTTCGGTATCTCTGCGCTTATGGTGCTATCTGCGATTGCAGTACCAGCA
ATTGCGTTACTCGGCGGATACTCGGTAGTAGAAGCGGTAAACAGCTTGGGTGGTGTGGCTGAACTACAAAAAGTACAACC
AGTACAACCTATCGACTTTTCAGTAGCGCTAGCAATGGTGGTTGGCTCATTCATCAGTGCGGGTACGTTAACCGCAGACT
TTGTTCGATTCGGCAAGAAGCCAAAAGGCGCAGTGATGGTCACGATGGTGGCATTCTTTATCGGTAACTCGCTGATGTTC
ATCTTCGGCGCAGCTGGTGCGGCGGTAACTGGCCAATCAGACATTTCAGAAGTGATGATCGCTCAAGGTCTTCTAATCCC
AGCTATCATCGTGCTTGGTTTGAACATTTGGACAACCAACGACAATGCGCTTTACGCATCGGGCCTAGGTTTCTCAAACA
TCACTGGTTTGCCAAGCAAATACATCTCTATGGCGAACGGTTTAGTCGGTACATTGTGTGCACTATGGTTGTACAATAAC
TTTGTAGGCTGGTTAACTTTCCTATCGCTTGCAATTCCACCAATTGGCGGTGTAATCATTGCGGACTTCTTCATGAACCG
TAAACGTTACACAAATTTCGCAGCAGCAGAGTTCCAAACTGTTAACTGGGCTGGCATTATCGCAGTGGCGATTGGTGTTG
CAGCTGGTCACTTCCTTCCGGGAGTGGTACCTGTAAACGCAGTACTGGGCGGCACAATCAGCTACCTGATTCTAAATCCT
ATTCTTAATAAAAAGACACTGGCACAACAGCCAGCGTAA

Upstream 100 bases:

>100_bases
AAAACTCATTGACTATGAGAGTTACATCACCATAATACGCGCCGTTTGCCCAGAAATTGGGATCTACAATTTGTTTTAAT
TTTTCTTTGCGGAGGTAAAA

Downstream 100 bases:

>100_bases
GGAACCATCATGACAACACTATTGATCAAGAACGCAACGCTTAAGGGACAGGAAGGTCTCCAGCAAATTTTGATTGAGGA
TGGTCAATTCAAGCGTATTG

Product: cytosine permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAADNNYSLGPVPNTARKGVASLTMVMLGLTFFSASMWTGGSLGTGLSFDDFFLAVLIGNLILGIYTSFLGYIGASTGLS
THLLARFSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPVNKATGIDTNTLIIISGLLMTATVYFGISALMVLSAIAVPA
IALLGGYSVVEAVNSLGGVAELQKVQPVQPIDFSVALAMVVGSFISAGTLTADFVRFGKKPKGAVMVTMVAFFIGNSLMF
IFGAAGAAVTGQSDISEVMIAQGLLIPAIIVLGLNIWTTNDNALYASGLGFSNITGLPSKYISMANGLVGTLCALWLYNN
FVGWLTFLSLAIPPIGGVIIADFFMNRKRYTNFAAAEFQTVNWAGIIAVAIGVAAGHFLPGVVPVNAVLGGTISYLILNP
ILNKKTLAQQPA

Sequences:

>Translated_412_residues
MAADNNYSLGPVPNTARKGVASLTMVMLGLTFFSASMWTGGSLGTGLSFDDFFLAVLIGNLILGIYTSFLGYIGASTGLS
THLLARFSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPVNKATGIDTNTLIIISGLLMTATVYFGISALMVLSAIAVPA
IALLGGYSVVEAVNSLGGVAELQKVQPVQPIDFSVALAMVVGSFISAGTLTADFVRFGKKPKGAVMVTMVAFFIGNSLMF
IFGAAGAAVTGQSDISEVMIAQGLLIPAIIVLGLNIWTTNDNALYASGLGFSNITGLPSKYISMANGLVGTLCALWLYNN
FVGWLTFLSLAIPPIGGVIIADFFMNRKRYTNFAAAEFQTVNWAGIIAVAIGVAAGHFLPGVVPVNAVLGGTISYLILNP
ILNKKTLAQQPA
>Mature_411_residues
AADNNYSLGPVPNTARKGVASLTMVMLGLTFFSASMWTGGSLGTGLSFDDFFLAVLIGNLILGIYTSFLGYIGASTGLST
HLLARFSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPVNKATGIDTNTLIIISGLLMTATVYFGISALMVLSAIAVPAI
ALLGGYSVVEAVNSLGGVAELQKVQPVQPIDFSVALAMVVGSFISAGTLTADFVRFGKKPKGAVMVTMVAFFIGNSLMFI
FGAAGAAVTGQSDISEVMIAQGLLIPAIIVLGLNIWTTNDNALYASGLGFSNITGLPSKYISMANGLVGTLCALWLYNNF
VGWLTFLSLAIPPIGGVIIADFFMNRKRYTNFAAAEFQTVNWAGIIAVAIGVAAGHFLPGVVPVNAVLGGTISYLILNPI
LNKKTLAQQPA

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=408, Percent_Identity=77.9411764705882, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 42726; Mature: 42595

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
AADNNYSLGPVPNTARKGVASLTMVMLGLTFFSASMWTGGSLGTGLSFDDFFLAVLIGN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LILGIYTSFLGYIGASTGLSTHLLARFSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPV
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHEEC
NKATGIDTNTLIIISGLLMTATVYFGISALMVLSAIAVPAIALLGGYSVVEAVNSLGGVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
ELQKVQPVQPIDFSVALAMVVGSFISAGTLTADFVRFGKKPKGAVMVTMVAFFIGNSLMF
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
IFGAAGAAVTGQSDISEVMIAQGLLIPAIIVLGLNIWTTNDNALYASGLGFSNITGLPSK
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCCCCCCHH
YISMANGLVGTLCALWLYNNFVGWLTFLSLAIPPIGGVIIADFFMNRKRYTNFAAAEFQT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHEEE
VNWAGIIAVAIGVAAGHFLPGVVPVNAVLGGTISYLILNPILNKKTLAQQPA
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]