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The map label for this gene is codA [H]

Identifier: 156976546

GI number: 156976546

Start: 552226

End: 553503

Strand: Reverse

Name: codA [H]

Synonym: VIBHAR_05319

Alternate gene names: 156976546

Gene position: 553503-552226 (Counterclockwise)

Preceding gene: 156976547

Following gene: 156976544

Centisome position: 25.11

GC content: 47.18

Gene sequence:

>1278_bases
ATGACAACACTATTGATCAAGAACGCAACGCTTAAGGGACAGGAAGGTCTCCAGCAAATTTTGATTGAGGATGGTCAATT
CAAGCGTATTGAAGACAATAATGTAGAACTAAATTACACAGGTGATGTTCTTGATGCGGAGGGCGGCATGGCTGTCGCAC
CTTTCTGTGAGCCGCATATTCACCTAGACACTACCCAAACCGCCGGTGAGCCGAACTGGAACATCTCCGGTACACTTTTC
GAAGGCATCGAGCGTTGGGCTGAGCGCAAAGAGACGCTGTCGATTGAAGACGTGAAATCACGCGCTAAGCAAACTCTGAA
ATGGCAAATTGCAAACGGCTTACAACACGTTCGTACCCACGTTGACGTTTCTGACCCTACCCTTATTGCTCTAAAAGCAA
TGGTAGAAGTTCGTGAAGAAATGAAAGAGTGGGTAGACATTCAAATCGTTGCGTTTCCGCAAGAAGGCATTCTGTCTTAC
CCGAATGGTAAAGAGCTTCTAGAAGAGGCGGTTCAGCTGGGTGCTGACGTTATTGGTGCAATCCCTCACTTTGAATTCAC
TCGTGAGTACGGCATCGAGTCTCTGCACTACGTTTTCGAGCTGGCGCAAAAATACGACCGTTTGATCGACGTGCACTGTG
ATGAGATCGATGACGAGCAATCACGCTTTGTTGAAACGCTTGCAGCACTAGCGCATAAGTTCAACATGGGCCACAAGGTA
ACCGCAAGCCATACAACAGCGATGGGCTCTTACAATGGTGCGTACGCATCTCGCCTATTCCGTTTGCTGCGCATGTCTGG
TATCAACTTCGTTGCAAACCCATTGGTCAACATCCACCTTCAAGGCCGTTTTGATGATTATCCTAAACGCCGTGGTGTGA
CTCGCGTAAAAGAAATGCTGAATGCAAACATCAACGTATGTTTTGGTCACGATGATGTATTTGACCCTTGGTATCCACTA
GGTACTGCAAACATGCTACAAGTACTGCATATGGGTCTGCATGTGTGTCAGGTGATGGGTTACGATCAAATCAACAACTC
GCTTGATCTGATCAGCACGAATTCAGCACGCACACTGAACATTCAAGACAAGCACGGCATTGAAGCAGGTAAGCCAGGTA
GCTTATTGATTCTTCCTGCGGAAAATGGTTTTGATGCAGTTCGTCGTCAGGTGCCAGTTCGTTACTCTGTTCGTCACGGT
AAAGTGATTGCAGAAACGCAACCAGCGACAACACACATTCACCTTGGTGAACAAGAGCAAGTGACCTACAAACGCTAA

Upstream 100 bases:

>100_bases
ACCTGTAAACGCAGTACTGGGCGGCACAATCAGCTACCTGATTCTAAATCCTATTCTTAATAAAAAGACACTGGCACAAC
AGCCAGCGTAAGGAACCATC

Downstream 100 bases:

>100_bases
TCACTGAGCTTCAAGCACAAAAAAAGGGTCTGACTTACATCAGACCCTTTTTTTATTTTTTCAAGCGCTGCGTTAGCTGT
CTACGGCAACTAATGACATT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTTLLIKNATLKGQEGLQQILIEDGQFKRIEDNNVELNYTGDVLDAEGGMAVAPFCEPHIHLDTTQTAGEPNWNISGTLF
EGIERWAERKETLSIEDVKSRAKQTLKWQIANGLQHVRTHVDVSDPTLIALKAMVEVREEMKEWVDIQIVAFPQEGILSY
PNGKELLEEAVQLGADVIGAIPHFEFTREYGIESLHYVFELAQKYDRLIDVHCDEIDDEQSRFVETLAALAHKFNMGHKV
TASHTTAMGSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGVTRVKEMLNANINVCFGHDDVFDPWYPL
GTANMLQVLHMGLHVCQVMGYDQINNSLDLISTNSARTLNIQDKHGIEAGKPGSLLILPAENGFDAVRRQVPVRYSVRHG
KVIAETQPATTHIHLGEQEQVTYKR

Sequences:

>Translated_425_residues
MTTLLIKNATLKGQEGLQQILIEDGQFKRIEDNNVELNYTGDVLDAEGGMAVAPFCEPHIHLDTTQTAGEPNWNISGTLF
EGIERWAERKETLSIEDVKSRAKQTLKWQIANGLQHVRTHVDVSDPTLIALKAMVEVREEMKEWVDIQIVAFPQEGILSY
PNGKELLEEAVQLGADVIGAIPHFEFTREYGIESLHYVFELAQKYDRLIDVHCDEIDDEQSRFVETLAALAHKFNMGHKV
TASHTTAMGSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGVTRVKEMLNANINVCFGHDDVFDPWYPL
GTANMLQVLHMGLHVCQVMGYDQINNSLDLISTNSARTLNIQDKHGIEAGKPGSLLILPAENGFDAVRRQVPVRYSVRHG
KVIAETQPATTHIHLGEQEQVTYKR
>Mature_424_residues
TTLLIKNATLKGQEGLQQILIEDGQFKRIEDNNVELNYTGDVLDAEGGMAVAPFCEPHIHLDTTQTAGEPNWNISGTLFE
GIERWAERKETLSIEDVKSRAKQTLKWQIANGLQHVRTHVDVSDPTLIALKAMVEVREEMKEWVDIQIVAFPQEGILSYP
NGKELLEEAVQLGADVIGAIPHFEFTREYGIESLHYVFELAQKYDRLIDVHCDEIDDEQSRFVETLAALAHKFNMGHKVT
ASHTTAMGSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGVTRVKEMLNANINVCFGHDDVFDPWYPLG
TANMLQVLHMGLHVCQVMGYDQINNSLDLISTNSARTLNIQDKHGIEAGKPGSLLILPAENGFDAVRRQVPVRYSVRHGK
VIAETQPATTHIHLGEQEQVTYKR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=420, Percent_Identity=75.4761904761905, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=396, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47880; Mature: 47749

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLIKNATLKGQEGLQQILIEDGQFKRIEDNNVELNYTGDVLDAEGGMAVAPFCEPHI
CCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEEECCCEEECCCCEEECCCCCCCE
HLDTTQTAGEPNWNISGTLFEGIERWAERKETLSIEDVKSRAKQTLKWQIANGLQHVRTH
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVSDPTLIALKAMVEVREEMKEWVDIQIVAFPQEGILSYPNGKELLEEAVQLGADVIGA
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHC
IPHFEFTREYGIESLHYVFELAQKYDRLIDVHCDEIDDEQSRFVETLAALAHKFNMGHKV
CCCCHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
TASHTTAMGSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGVTRVKEML
ECCCCEECCCCCHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHCCHHHHHHHH
NANINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQVMGYDQINNSLDLISTNSARTLN
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCEEEEE
IQDKHGIEAGKPGSLLILPAENGFDAVRRQVPVRYSVRHGKVIAETQPATTHIHLGEQEQ
CCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCEEEEECCCCCC
VTYKR
CCCCC
>Mature Secondary Structure 
TTLLIKNATLKGQEGLQQILIEDGQFKRIEDNNVELNYTGDVLDAEGGMAVAPFCEPHI
CEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEEECCCEEECCCCEEECCCCCCCE
HLDTTQTAGEPNWNISGTLFEGIERWAERKETLSIEDVKSRAKQTLKWQIANGLQHVRTH
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVSDPTLIALKAMVEVREEMKEWVDIQIVAFPQEGILSYPNGKELLEEAVQLGADVIGA
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHC
IPHFEFTREYGIESLHYVFELAQKYDRLIDVHCDEIDDEQSRFVETLAALAHKFNMGHKV
CCCCHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
TASHTTAMGSYNGAYASRLFRLLRMSGINFVANPLVNIHLQGRFDDYPKRRGVTRVKEML
ECCCCEECCCCCHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHCCHHHHHHHH
NANINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQVMGYDQINNSLDLISTNSARTLN
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCCEEEEE
IQDKHGIEAGKPGSLLILPAENGFDAVRRQVPVRYSVRHGKVIAETQPATTHIHLGEQEQ
CCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCEEEEECCCCCC
VTYKR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]