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The map label for this gene is ribB [H]

Identifier: 156976538

GI number: 156976538

Start: 545001

End: 545657

Strand: Reverse

Name: ribB [H]

Synonym: VIBHAR_05311

Alternate gene names: 156976538

Gene position: 545657-545001 (Counterclockwise)

Preceding gene: 156976539

Following gene: 156976536

Centisome position: 24.76

GC content: 48.4

Gene sequence:

>657_bases
ATGAATCAGTCATCACTACTTGCCGAATTTGGCGACCCAATTACTCGCGTTGAAAACGCACTTATCGCACTTAAAGAAGG
CCGTGGCGTGCTTCTTCTCGACGATGAAGATCGTGAAAACGAAGGCGACATCATTTATTCCGTAGAACACCTGACTAATG
AGCAAATGGCTCTGATGATCCGCGAATGCAGCGGCATTGTTTGCCTGTGTCTGACCGATGCTCAAGCAGACAAATTGGAA
CTGCCACCAATGGTTGTGAACAACAACAGCGCAAACCAAACGGCCTTCACGGTTTCTATTGAAGCGAAACAAGGTGTAAC
CACTGGCGTTTCTGCCGCTGACCGCGTAACAACCATCAAAACAGCAGCAAACCCAAATACAAAACCAGATGACTTAGCTC
GTCCTGGTCACGTCTTCCCTCTACGCGCTCGTCCTGGTGGCGTAATGACTCGCCGTGGTCATACAGAAGGCACTATCGAT
TTGATGCAAATGGCAGGTTTACAGCCTGCTGGCGTGCTGTGTGAGGTGACAAACCCAGATGGCACCATGGCAAAAGCACC
AGAAATCGTTGCGTTTGGTCGTTTACACAACATGCCAGTACTGACCATCGAAGATATGGTGGCTTACCGCAATCAATTTG
ATTTAAAGCTTGCATAA

Upstream 100 bases:

>100_bases
GCGTGGGTTTGTGCCAACTTACCGTTGGCGGCTCAGCGCATGCATAAAATGTGACGATCCCTCATACCGCCCTGATTCTG
GTGATATTTAGGAGTTAACC

Downstream 100 bases:

>100_bases
TCGACACGTCGTCAATCTCGAAAAAAGCCGCTGAATTCAGCTAACTCCTATCACTTAACGTGTTTGGAGCGAACTGGATA
GCGAGTCTTACTCATACGAA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MNQSSLLAEFGDPITRVENALIALKEGRGVLLLDDEDRENEGDIIYSVEHLTNEQMALMIRECSGIVCLCLTDAQADKLE
LPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAADRVTTIKTAANPNTKPDDLARPGHVFPLRARPGGVMTRRGHTEGTID
LMQMAGLQPAGVLCEVTNPDGTMAKAPEIVAFGRLHNMPVLTIEDMVAYRNQFDLKLA

Sequences:

>Translated_218_residues
MNQSSLLAEFGDPITRVENALIALKEGRGVLLLDDEDRENEGDIIYSVEHLTNEQMALMIRECSGIVCLCLTDAQADKLE
LPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAADRVTTIKTAANPNTKPDDLARPGHVFPLRARPGGVMTRRGHTEGTID
LMQMAGLQPAGVLCEVTNPDGTMAKAPEIVAFGRLHNMPVLTIEDMVAYRNQFDLKLA
>Mature_218_residues
MNQSSLLAEFGDPITRVENALIALKEGRGVLLLDDEDRENEGDIIYSVEHLTNEQMALMIRECSGIVCLCLTDAQADKLE
LPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAADRVTTIKTAANPNTKPDDLARPGHVFPLRARPGGVMTRRGHTEGTID
LMQMAGLQPAGVLCEVTNPDGTMAKAPEIVAFGRLHNMPVLTIEDMVAYRNQFDLKLA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=216, Percent_Identity=64.8148148148148, Blast_Score=288, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=40.6862745098039, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23571; Mature: 23571

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSSLLAEFGDPITRVENALIALKEGRGVLLLDDEDRENEGDIIYSVEHLTNEQMALMI
CCCHHHHHHHCCHHHHHHHEEEEEECCCEEEEECCCCCCCCCCEEEEEHHCCCCHHHHEE
RECSGIVCLCLTDAQADKLELPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAADRVTTIK
ECCCCEEEEEEECCCCCCEECCCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEE
TAANPNTKPDDLARPGHVFPLRARPGGVMTRRGHTEGTIDLMQMAGLQPAGVLCEVTNPD
ECCCCCCCCHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCC
GTMAKAPEIVAFGRLHNMPVLTIEDMVAYRNQFDLKLA
CCCCCCCCEEEECCCCCCCEEEHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MNQSSLLAEFGDPITRVENALIALKEGRGVLLLDDEDRENEGDIIYSVEHLTNEQMALMI
CCCHHHHHHHCCHHHHHHHEEEEEECCCEEEEECCCCCCCCCCEEEEEHHCCCCHHHHEE
RECSGIVCLCLTDAQADKLELPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAADRVTTIK
ECCCCEEEEEEECCCCCCEECCCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEE
TAANPNTKPDDLARPGHVFPLRARPGGVMTRRGHTEGTIDLMQMAGLQPAGVLCEVTNPD
ECCCCCCCCHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCC
GTMAKAPEIVAFGRLHNMPVLTIEDMVAYRNQFDLKLA
CCCCCCCCEEEECCCCCCCEEEHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]