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The map label for this gene is gpwA [H]

Identifier: 156976536

GI number: 156976536

Start: 542902

End: 543447

Strand: Reverse

Name: gpwA [H]

Synonym: VIBHAR_05309

Alternate gene names: 156976536

Gene position: 543447-542902 (Counterclockwise)

Preceding gene: 156976538

Following gene: 156976535

Centisome position: 24.66

GC content: 46.15

Gene sequence:

>546_bases
ATGAAGGGAATCACTCGCAACGCACTTATCGCAACACTACTCTCCACCAGCTCTATGATTTTTGCATCGAGCTGTCCAGA
TATCTTGCAAGGAAAACAAAGACTTCTCAATTCAACGGAAGAAATAGCGCTGTGTGATGCCTTCAAAGGCAAGACACTGC
TGGTTGTGAACACGGCGAGTCAGTGTGGCTTTACTCCCCAATTCGAGCAGTTGGAACAACTACACCAAACCTATAAAGAT
CAAAACTTTGCCGTTGTGGGATTTCCTAGTAACGACTTTCGCCAAGACCGCGGCAGCGAAGAGAAGACTGCGAAAATCTG
TTACCTCGACTATGGTGTCACCTTCCCTATGATGGCGCGAACCTCTGTTCTTGGTGAGAACGCAAACCCAGTATTTGCCG
AGATAACCAACCAGGCGGGCGTTACACCAAAATGGAATTTCTACAAGTTCCTCATCAACAAAGACGGCAAAGTTGTTGCG
ACCTTTCCAAGTTCAACTTCCCCGACAAGTACTACGCTTACTAACATGATTGAACAGCAACTATAA

Upstream 100 bases:

>100_bases
TGCTTAACTGATCGGAGTTAGCTGAATTCAGCGGCTTTTTTGATCGATTTGATTCCTTTTCTAGTAGTTATACTTAATAA
AAACAAAAGGAATCAACATC

Downstream 100 bases:

>100_bases
GGAAAGCGGCCATGGCGACTACACGTACGACAATGCTGCAATTGGGCTATTTAGGACTGCTGCCATTTATGTTCAGCTTG
GTTCTCATCGGCACGGAAAG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKGITRNALIATLLSTSSMIFASSCPDILQGKQRLLNSTEEIALCDAFKGKTLLVVNTASQCGFTPQFEQLEQLHQTYKD
QNFAVVGFPSNDFRQDRGSEEKTAKICYLDYGVTFPMMARTSVLGENANPVFAEITNQAGVTPKWNFYKFLINKDGKVVA
TFPSSTSPTSTTLTNMIEQQL

Sequences:

>Translated_181_residues
MKGITRNALIATLLSTSSMIFASSCPDILQGKQRLLNSTEEIALCDAFKGKTLLVVNTASQCGFTPQFEQLEQLHQTYKD
QNFAVVGFPSNDFRQDRGSEEKTAKICYLDYGVTFPMMARTSVLGENANPVFAEITNQAGVTPKWNFYKFLINKDGKVVA
TFPSSTSPTSTTLTNMIEQQL
>Mature_181_residues
MKGITRNALIATLLSTSSMIFASSCPDILQGKQRLLNSTEEIALCDAFKGKTLLVVNTASQCGFTPQFEQLEQLHQTYKD
QNFAVVGFPSNDFRQDRGSEEKTAKICYLDYGVTFPMMARTSVLGENANPVFAEITNQAGVTPKWNFYKFLINKDGKVVA
TFPSSTSPTSTTLTNMIEQQL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=136, Percent_Identity=34.5588235294118, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI192455698, Length=117, Percent_Identity=36.7521367521368, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI75709200, Length=131, Percent_Identity=34.3511450381679, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI90903240, Length=131, Percent_Identity=34.3511450381679, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=34.9397590361446, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506887, Length=137, Percent_Identity=34.3065693430657, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535473, Length=127, Percent_Identity=32.2834645669291, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993584, Length=129, Percent_Identity=29.4573643410853, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=144, Percent_Identity=46.5277777777778, Blast_Score=134, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6319721, Length=131, Percent_Identity=48.0916030534351, Blast_Score=133, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322826, Length=142, Percent_Identity=35.9154929577465, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24656772, Length=133, Percent_Identity=35.3383458646617, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24656767, Length=133, Percent_Identity=35.3383458646617, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24656777, Length=133, Percent_Identity=35.3383458646617, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI85726443, Length=136, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20012; Mature: 20012

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGITRNALIATLLSTSSMIFASSCPDILQGKQRLLNSTEEIALCDAFKGKTLLVVNTAS
CCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHEEEEECCCCCEEEEEECHH
QCGFTPQFEQLEQLHQTYKDQNFAVVGFPSNDFRQDRGSEEKTAKICYLDYGVTFPMMAR
HCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCEEEEEEEECCCCCHHHHH
TSVLGENANPVFAEITNQAGVTPKWNFYKFLINKDGKVVATFPSSTSPTSTTLTNMIEQQ
HHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHC
L
C
>Mature Secondary Structure
MKGITRNALIATLLSTSSMIFASSCPDILQGKQRLLNSTEEIALCDAFKGKTLLVVNTAS
CCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHEEEEECCCCCEEEEEECHH
QCGFTPQFEQLEQLHQTYKDQNFAVVGFPSNDFRQDRGSEEKTAKICYLDYGVTFPMMAR
HCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCEEEEEEEECCCCCHHHHH
TSVLGENANPVFAEITNQAGVTPKWNFYKFLINKDGKVVATFPSSTSPTSTTLTNMIEQQ
HHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA