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The map label for this gene is aaeR [H]

Identifier: 156976496

GI number: 156976496

Start: 514579

End: 515445

Strand: Direct

Name: aaeR [H]

Synonym: VIBHAR_05269

Alternate gene names: 156976496

Gene position: 514579-515445 (Clockwise)

Preceding gene: 156976494

Following gene: 156976497

Centisome position: 23.35

GC content: 45.21

Gene sequence:

>867_bases
ATGAATAAGCTGCGGTTAATGTCTCTGTTCGTTCATATTGTGGAGTGTGGCTCAATCTCGAAAGCAGCAGAGAAGTTGGA
ACTCTCCAAGTCGGTGCTCAGCTCTGCTCTTAAGCAGCTCGAGCAAGAGCTAGATACGTGTTTACTCAAGCGTACGACGA
GGAGACAAACGTTGACCTCTGCGGGCGAACGCTTTTATAAACAATGTGCGCAGATGACAAAACAGGCGGAAGAGGCGTGG
TTAGAAGCGGCAGAGTTAAAGCAAGTCCCAATGGGAACTCTTACCGTTACCGCGCCAAATGCGTTGATGCGTTCTATAGT
ATTGCCTGCTTTAACGGAGGCTTTTGCACAGTACCCTGATGTGCATTTAAATTTAGTCAGCGACGATAAGCATGTTGATA
TTGTTCAGCAGGATATTGATCTTGCAGTGAGAGTTGGAGCGTCTGGTGATTCGAACATTAAACAACGTAAAGTAGGGCAG
TTTTGTGATGTATTATGTCGAGCTAAAGAGATGCATACTGATATTGAAAGTACTTTTTATATCGCTCAACACTGGCAGAT
AGAACCGATTGCCCATAACTTCACTCTGAATGGTCAAGATCACCTAGTGCAATACTCAGTAAAGCATCGTGCAAACACCG
TGTTCGATGTGGCGAGCCTTCTAGAAATGGGACTAGGCTTTGGGATTCTGCCAGATTTTATGCTGGCCTCGAATCCACTT
CTTGAACCTGTGCCTGATGCGAAAGCATCGAAAGCGAACCCGATTTACGTGTTGCATCCTTACCATGCACATGTGCCGAT
GTCGGTGACATTAGCGATAAAGGCAATTGAAGATCGTATCGAAGAAGTGATTTCATGTGAAAACTGA

Upstream 100 bases:

>100_bases
TTGGTGTTTGTTTATGTGGCAATCATAGGGTTAGAATTAAAACTGAAAAACAAACAAATAAGAAATAAGTGTTCTGTTAA
ATAGAACAATAAGGAAGGCG

Downstream 100 bases:

>100_bases
GGGTTAGAGCTGAATGAAAAACAGAGGTGATAGAAATTAAACCTGCTGCGTTTTTATTCAGGATCAACCTTCATCATTAT
TTCACTCCACGTTCTAACTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNKLRLMSLFVHIVECGSISKAAEKLELSKSVLSSALKQLEQELDTCLLKRTTRRQTLTSAGERFYKQCAQMTKQAEEAW
LEAAELKQVPMGTLTVTAPNALMRSIVLPALTEAFAQYPDVHLNLVSDDKHVDIVQQDIDLAVRVGASGDSNIKQRKVGQ
FCDVLCRAKEMHTDIESTFYIAQHWQIEPIAHNFTLNGQDHLVQYSVKHRANTVFDVASLLEMGLGFGILPDFMLASNPL
LEPVPDAKASKANPIYVLHPYHAHVPMSVTLAIKAIEDRIEEVISCEN

Sequences:

>Translated_288_residues
MNKLRLMSLFVHIVECGSISKAAEKLELSKSVLSSALKQLEQELDTCLLKRTTRRQTLTSAGERFYKQCAQMTKQAEEAW
LEAAELKQVPMGTLTVTAPNALMRSIVLPALTEAFAQYPDVHLNLVSDDKHVDIVQQDIDLAVRVGASGDSNIKQRKVGQ
FCDVLCRAKEMHTDIESTFYIAQHWQIEPIAHNFTLNGQDHLVQYSVKHRANTVFDVASLLEMGLGFGILPDFMLASNPL
LEPVPDAKASKANPIYVLHPYHAHVPMSVTLAIKAIEDRIEEVISCEN
>Mature_288_residues
MNKLRLMSLFVHIVECGSISKAAEKLELSKSVLSSALKQLEQELDTCLLKRTTRRQTLTSAGERFYKQCAQMTKQAEEAW
LEAAELKQVPMGTLTVTAPNALMRSIVLPALTEAFAQYPDVHLNLVSDDKHVDIVQQDIDLAVRVGASGDSNIKQRKVGQ
FCDVLCRAKEMHTDIESTFYIAQHWQIEPIAHNFTLNGQDHLVQYSVKHRANTVFDVASLLEMGLGFGILPDFMLASNPL
LEPVPDAKASKANPIYVLHPYHAHVPMSVTLAIKAIEDRIEEVISCEN

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=26.4214046822742, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=28.1786941580756, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87081978, Length=187, Percent_Identity=31.5508021390374, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693193, Length=166, Percent_Identity=31.9277108433735, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=33.0935251798561, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787589, Length=150, Percent_Identity=29.3333333333333, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789440, Length=139, Percent_Identity=30.2158273381295, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=32.6530612244898, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32121; Mature: 32121

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLRLMSLFVHIVECGSISKAAEKLELSKSVLSSALKQLEQELDTCLLKRTTRRQTLTS
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERFYKQCAQMTKQAEEAWLEAAELKQVPMGTLTVTAPNALMRSIVLPALTEAFAQYPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
VHLNLVSDDKHVDIVQQDIDLAVRVGASGDSNIKQRKVGQFCDVLCRAKEMHTDIESTFY
CEEEEECCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHEE
IAQHWQIEPIAHNFTLNGQDHLVQYSVKHRANTVFDVASLLEMGLGFGILPDFMLASNPL
EEECCEECEEECCEEECCCHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
LEPVPDAKASKANPIYVLHPYHAHVPMSVTLAIKAIEDRIEEVISCEN
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKLRLMSLFVHIVECGSISKAAEKLELSKSVLSSALKQLEQELDTCLLKRTTRRQTLTS
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERFYKQCAQMTKQAEEAWLEAAELKQVPMGTLTVTAPNALMRSIVLPALTEAFAQYPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
VHLNLVSDDKHVDIVQQDIDLAVRVGASGDSNIKQRKVGQFCDVLCRAKEMHTDIESTFY
CEEEEECCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHEE
IAQHWQIEPIAHNFTLNGQDHLVQYSVKHRANTVFDVASLLEMGLGFGILPDFMLASNPL
EEECCEECEEECCEEECCCHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
LEPVPDAKASKANPIYVLHPYHAHVPMSVTLAIKAIEDRIEEVISCEN
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]