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The map label for this gene is katA [H]

Identifier: 156976419

GI number: 156976419

Start: 447924

End: 449360

Strand: Reverse

Name: katA [H]

Synonym: VIBHAR_05192

Alternate gene names: 156976419

Gene position: 449360-447924 (Counterclockwise)

Preceding gene: 156976420

Following gene: 156976417

Centisome position: 20.39

GC content: 48.71

Gene sequence:

>1437_bases
ATGAGCAAGAAATTGACTACAGCAGCAGGTTGCCCTGTCGCACATAACCAAAACGTTATGACTGCAGGTCCTCGTGGCCC
TCAACTATTACAAGACGTTTGGTTCCTTGAAAAATTGGCACACTTTGACCGCGAAGTGATCCCTGAGCGTCGTATGCACG
CAAAAGGTTCTGGTGCTTACGGTACCTTCACAGTAACGCACGACATCACAAAGTACACTCGTGCTAAGATCTTCTCTGAC
ATAGGCAAAAAAACAGAACTATTCGCTCGCTTCACTACTGTAGCTGGTGAGCGCGGTGCAGCAGACGCAGAACGCGACAT
CCGTGGTTTCGCACTAAAATTCTACACTGAAGAAGGTAACTGGGACTTGGTTGGTAACAACACACCCGTATTCTTCCTAC
GTGACCCACTAAAATTCCCAGACCTAAACCACGCAGTAAAACGCGACCCTCGCACTAACATGCGTAGCTCTACCAACAAC
TGGGATTTCTGGACATCACTACCAGAAGCGTTCCACCAAGTGACTATCGTAATGAGTGACCGTGGTATCCCAGCGTCTTA
CCGTCATATGCATGGTTTTGGTAGCCACACATTCAGCTTCATCAACGCAGAAAACGAGCGTTACTGGGTGAAATTCCACT
TCAAAACTCAGCAAGGCATCAAAAACCTAACTGACCAAGAAGCAGAAGCAATCGTAGGTAAAGACCGCGAAAGCCATCAC
CGTGACCTTTACGAAGCGATTGAGCGTCAAGACTTCCCTAAATGGAAGATGTACGTACAGATCATGCCTGAGTTAGAAGC
GGATGAAGTCAACTTCAACCCATTCGACCTAACACGTGTATGGTCTCAAAAAGACTACCCACTGATCCCAGTTGGTGAGT
TCGAACTGAACCGTAACCCAGAAAACTTCTACGCAGAAGTTGAACAATCAGCGTTCAACCCAGCAGCAGTAGTACCTGGT
ATCGGCTTCTCTCCAGATAAGATGCTACAAGGTCGTCTGTTCGCTTACGGCGATGCTCAGCGTTACCGTCTAGGTGTGAA
CCATCATCAAATCCCAGTGAATGCACCTCGTTGCCCTGTTCACAGCTACCACCGCGATGGTGCAATGCGCGTTGATGGCA
ACTTTGGTTCAACACTAGGTTACGAGCCAAACTACAAACAAGAATGGGCAGAGCAACCAGATTACTCTGAGCCACCTCTA
CGCATCAACGGCAACGCTGATCACTACGATCACCGTGTAGACGAAGACTACTTCAGCCAAGCGGGTGACCTATTCCGTCT
GATGAGTGAAGAGCAACGTCAAACTCTGTTCGACAACACAGCTCGCGCAATGGACGGTGTGCCAGAGTTCATCCAACAGC
GCCACGTTCAACACGCATACCAAGCAGACGAAGCGTACGGCAAAGGTCTTGAGATTGCGCTAGGCTTAAACAAGTAA

Upstream 100 bases:

>100_bases
AACAGTTTTTTTCTTCTCAATTACAGCGTTATTCTCCTCGCATCACTTTCGGATTCATCCAAAAGACAAGATTTATTATC
ACTATTGCAAGGAAATTCAA

Downstream 100 bases:

>100_bases
GCGAACGCTGTAATCATCACACTGTGTGATTAAAAGACATAAAAAAGGAGGTGCCCAACAGCACCTCCTGATTTCAAATC
ACTAATCCTTAATCACTAGT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSKKLTTAAGCPVAHNQNVMTAGPRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITKYTRAKIFSD
IGKKTELFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSSTNN
WDFWTSLPEAFHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAENERYWVKFHFKTQQGIKNLTDQEAEAIVGKDRESHH
RDLYEAIERQDFPKWKMYVQIMPELEADEVNFNPFDLTRVWSQKDYPLIPVGEFELNRNPENFYAEVEQSAFNPAAVVPG
IGFSPDKMLQGRLFAYGDAQRYRLGVNHHQIPVNAPRCPVHSYHRDGAMRVDGNFGSTLGYEPNYKQEWAEQPDYSEPPL
RINGNADHYDHRVDEDYFSQAGDLFRLMSEEQRQTLFDNTARAMDGVPEFIQQRHVQHAYQADEAYGKGLEIALGLNK

Sequences:

>Translated_478_residues
MSKKLTTAAGCPVAHNQNVMTAGPRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITKYTRAKIFSD
IGKKTELFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSSTNN
WDFWTSLPEAFHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAENERYWVKFHFKTQQGIKNLTDQEAEAIVGKDRESHH
RDLYEAIERQDFPKWKMYVQIMPELEADEVNFNPFDLTRVWSQKDYPLIPVGEFELNRNPENFYAEVEQSAFNPAAVVPG
IGFSPDKMLQGRLFAYGDAQRYRLGVNHHQIPVNAPRCPVHSYHRDGAMRVDGNFGSTLGYEPNYKQEWAEQPDYSEPPL
RINGNADHYDHRVDEDYFSQAGDLFRLMSEEQRQTLFDNTARAMDGVPEFIQQRHVQHAYQADEAYGKGLEIALGLNK
>Mature_477_residues
SKKLTTAAGCPVAHNQNVMTAGPRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITKYTRAKIFSDI
GKKTELFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSSTNNW
DFWTSLPEAFHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAENERYWVKFHFKTQQGIKNLTDQEAEAIVGKDRESHHR
DLYEAIERQDFPKWKMYVQIMPELEADEVNFNPFDLTRVWSQKDYPLIPVGEFELNRNPENFYAEVEQSAFNPAAVVPGI
GFSPDKMLQGRLFAYGDAQRYRLGVNHHQIPVNAPRCPVHSYHRDGAMRVDGNFGSTLGYEPNYKQEWAEQPDYSEPPLR
INGNADHYDHRVDEDYFSQAGDLFRLMSEEQRQTLFDNTARAMDGVPEFIQQRHVQHAYQADEAYGKGLEIALGLNK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=471, Percent_Identity=50.7430997876858, Blast_Score=488, Evalue=1e-138,
Organism=Escherichia coli, GI48994891, Length=416, Percent_Identity=46.3942307692308, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25147792, Length=475, Percent_Identity=48.6315789473684, Blast_Score=466, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=48.6315789473684, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI71998444, Length=464, Percent_Identity=48.9224137931034, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320462, Length=486, Percent_Identity=45.679012345679, Blast_Score=390, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321525, Length=385, Percent_Identity=40.7792207792208, Blast_Score=293, Evalue=4e-80,
Organism=Drosophila melanogaster, GI17981717, Length=478, Percent_Identity=49.163179916318, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=478, Percent_Identity=46.234309623431, Blast_Score=446, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55008; Mature: 54877

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLTTAAGCPVAHNQNVMTAGPRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAY
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCE
GTFTVTHDITKYTRAKIFSDIGKKTELFARFTTVAGERGAADAERDIRGFALKFYTEEGN
EEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEEEEECCC
WDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSSTNNWDFWTSLPEAFHQVTIVMSD
EEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEC
RGIPASYRHMHGFGSHTFSFINAENERYWVKFHFKTQQGIKNLTDQEAEAIVGKDRESHH
CCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHH
RDLYEAIERQDFPKWKMYVQIMPELEADEVNFNPFDLTRVWSQKDYPLIPVGEFELNRNP
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCEEECCCC
ENFYAEVEQSAFNPAAVVPGIGFSPDKMLQGRLFAYGDAQRYRLGVNHHQIPVNAPRCPV
HHHHHHHHHHCCCCCEECCCCCCCHHHHHCCEEEEECCCHHEEECCCCCCCCCCCCCCCC
HSYHRDGAMRVDGNFGSTLGYEPNYKQEWAEQPDYSEPPLRINGNADHYDHRVDEDYFSQ
CCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHHHHH
AGDLFRLMSEEQRQTLFDNTARAMDGVPEFIQQRHVQHAYQADEAYGKGLEIALGLNK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SKKLTTAAGCPVAHNQNVMTAGPRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAY
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCE
GTFTVTHDITKYTRAKIFSDIGKKTELFARFTTVAGERGAADAERDIRGFALKFYTEEGN
EEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEEEEECCC
WDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSSTNNWDFWTSLPEAFHQVTIVMSD
EEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEC
RGIPASYRHMHGFGSHTFSFINAENERYWVKFHFKTQQGIKNLTDQEAEAIVGKDRESHH
CCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHH
RDLYEAIERQDFPKWKMYVQIMPELEADEVNFNPFDLTRVWSQKDYPLIPVGEFELNRNP
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCEEECCCC
ENFYAEVEQSAFNPAAVVPGIGFSPDKMLQGRLFAYGDAQRYRLGVNHHQIPVNAPRCPV
HHHHHHHHHHCCCCCEECCCCCCCHHHHHCCEEEEECCCHHEEECCCCCCCCCCCCCCCC
HSYHRDGAMRVDGNFGSTLGYEPNYKQEWAEQPDYSEPPLRINGNADHYDHRVDEDYFSQ
CCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHHHHH
AGDLFRLMSEEQRQTLFDNTARAMDGVPEFIQQRHVQHAYQADEAYGKGLEIALGLNK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9555890 [H]