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The map label for this gene is lrp [C]

Identifier: 156976156

GI number: 156976156

Start: 193427

End: 193912

Strand: Reverse

Name: lrp [C]

Synonym: VIBHAR_04927

Alternate gene names: 156976156

Gene position: 193912-193427 (Counterclockwise)

Preceding gene: 156976159

Following gene: 156976152

Centisome position: 8.8

GC content: 43.62

Gene sequence:

>486_bases
ATGACGTCAACGCCACCACTTTCCGTCGATAGTTTCGACCGAAAAATTCTCGACATTGTCCAGCATTCAAATAGAGCGAC
ATCAGACACTATTGCTGATCAGGTTGGGCTATCGCCAGCAGCGGTTCAGCGTCGATTAAAGCGCATGAGAGCTCAAGGGG
TAATACAAGCCGATATCTCTGTTGTTAACCCCAAGGCTGTAGGCCAAACCATGACTTTTGTTGTGCAAGTGACGTTGGAA
AGAGAAAGAGTCGACTTGATGCACAATTTTAAGAAAGAGATGACCGCAAATCGTTCGGTACAACAGTGTTACTATGTGAC
TGGAAGTTCAGACTTTATTCTTATTGTCACTGCGGCAGACATGGAAGGTTATGACAAATTTACACGAGAAGCGTTTTTCG
ACAATGCCAACATCAAAAGCTTTCAAACCAACGTAGTGATGGATAACGTGAAAGTGGGACTTACAATCCCAATTGATGAT
CAATGA

Upstream 100 bases:

>100_bases
CAAGACATTCGCTCATGAGTGAGGTCACAATTCGGAGCCAGAGCATGATTAGCTCACCATATGGCTTCCATCCATCACAG
GCAGAAAGGAATCGATCGTC

Downstream 100 bases:

>100_bases
CGAAAACAGAGAAAAGCTAGAAACGTTGTCAATGGTGGATATGAAAACGGCGCTTCCTTGCAAGCGCCGTTTAATGATTT
CACCCATCAGGTGGTTTGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTSTPPLSVDSFDRKILDIVQHSNRATSDTIADQVGLSPAAVQRRLKRMRAQGVIQADISVVNPKAVGQTMTFVVQVTLE
RERVDLMHNFKKEMTANRSVQQCYYVTGSSDFILIVTAADMEGYDKFTREAFFDNANIKSFQTNVVMDNVKVGLTIPIDD
Q

Sequences:

>Translated_161_residues
MTSTPPLSVDSFDRKILDIVQHSNRATSDTIADQVGLSPAAVQRRLKRMRAQGVIQADISVVNPKAVGQTMTFVVQVTLE
RERVDLMHNFKKEMTANRSVQQCYYVTGSSDFILIVTAADMEGYDKFTREAFFDNANIKSFQTNVVMDNVKVGLTIPIDD
Q
>Mature_160_residues
TSTPPLSVDSFDRKILDIVQHSNRATSDTIADQVGLSPAAVQRRLKRMRAQGVIQADISVVNPKAVGQTMTFVVQVTLER
ERVDLMHNFKKEMTANRSVQQCYYVTGSSDFILIVTAADMEGYDKFTREAFFDNANIKSFQTNVVMDNVKVGLTIPIDDQ

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=147, Percent_Identity=29.9319727891156, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=22.5165562913907, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 18021; Mature: 17890

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPPLSVDSFDRKILDIVQHSNRATSDTIADQVGLSPAAVQRRLKRMRAQGVIQADIS
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECEE
VVNPKAVGQTMTFVVQVTLERERVDLMHNFKKEMTANRSVQQCYYVTGSSDFILIVTAAD
EECCHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
MEGYDKFTREAFFDNANIKSFQTNVVMDNVKVGLTIPIDDQ
CCCHHHHHHHHHCCCCCCCEEEEEEEEECEEEEEEEECCCC
>Mature Secondary Structure 
TSTPPLSVDSFDRKILDIVQHSNRATSDTIADQVGLSPAAVQRRLKRMRAQGVIQADIS
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECEE
VVNPKAVGQTMTFVVQVTLERERVDLMHNFKKEMTANRSVQQCYYVTGSSDFILIVTAAD
EECCHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
MEGYDKFTREAFFDNANIKSFQTNVVMDNVKVGLTIPIDDQ
CCCHHHHHHHHHCCCCCCCEEEEEEEEECEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]