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The map label for this gene is sdaB [H]

Identifier: 156976128

GI number: 156976128

Start: 167858

End: 169228

Strand: Reverse

Name: sdaB [H]

Synonym: VIBHAR_04899

Alternate gene names: 156976128

Gene position: 169228-167858 (Counterclockwise)

Preceding gene: 156976130

Following gene: 156976127

Centisome position: 7.68

GC content: 49.16

Gene sequence:

>1371_bases
ATGCTGTCGATTTTCGATATTTTTAAAGTCGGTGTCGGTCCATCCAGTTCCCACACCAATGGCCCAATGCTCGCAGGTTA
CCATTTCACTCAACTACTTAGCGACTCTATGGCGAAAGTGCACAAGGTGCAAGTTGACCTTTATGGTTCTTTATCGCTGA
CAGGCAAAGGTCACCATACTGACCGTGCTACCGTACTTGGTTTGATGGGCAACAAACCCGATACCATCAAGATGACCAGT
GCCAAGAGTGCACTGCAACATACCATTGAACATGGCACGCTCTCTGTCGCTGGCGTGCATGAGATCGTGTTTAGTTATGA
TCACGATATCGTCTTCCACAGCGACAACCTCCCATTGCATGAAAATGGCATGACCATTACGGCTTTTGATGCTGTTGGCG
ATCAAGTCGCGTTTGAGACTTATTACTCCATTGGCGGTGGCTTTATTGCAACCGCGGCCGAGCTGGAAAATGGCAGCAGC
GAAGCGGAAGTGCAAGTGTGTTACCCGTTCAAATCAGCCGATGAAATGCTAGAGAAAGCAGAACAAAACGGCTTGAGCTT
GGGCGGAATGATCCTGCAAAACGAACGCGCGTTTCGTGAGCAGGAAGAGATCGATCAAAAAGCTGAGCAGATCTGGAAAG
TGATGTCGCTGTGCATGCAACGAGGCTTTGATACCGAAGGCATTCTCGAAGGCGGGTTGAACGTAACTCGCCGAGCGCCA
AACCTACTCAAAAAACTCGAAGCCAATGCGGCAGTCGAGAACGATCCAATGGAGATCATGGATTGGATTAACCTGTTTGC
TTTCGCAGTGAGTGAAGAGAATGCTGCAGGTGGTCAAGTAGTGACGTCACCAACCAATGGTGCTGCCGGTGTTATTCCTG
CGGTACTGATGTACTACCACCGCTTCATCAAAGAGCTGGACAACAAACAGTTGAAGGACTTCTTAGCAGTCGCGGGGGCG
ATTGGTATTTTATACAAAACCAACGCTTCTATTTCCGGTGCAGAGGTAGGTTGCCAGGGTGAAGTCGGGGTTTCGTCTTC
GATGGCAGCAGCAGGCTTAACCGCACTGCGCGGTGGCAGTAATGAACAAATCTGTATTGCCGCAGAAATCGCCATGGAGC
ATTCGCTTGGCATGACTTGTGACCCAATTGGTGGTCTGGTTCAGGTGCCGTGTATCGAGCGAAACGCGATGGGCGCGATG
AAAGCCATTAACGCATCACGCATGGCACTGAAACGCACCAGCAAATGTCTTATTTCATTAGATAAAGTTATCGAGACCAT
GTACCAGACTGGTAAAGACATGAATAAAAAATACCGTGAAACATCACTTGGTGGTCTGGCAGTGATTCATATGGCGCCAC
CATGCGAATAG

Upstream 100 bases:

>100_bases
CAAAAAATTGCTTTGCCAATACCCTCTCAGGCATTAACATCTAATTAACAATGTCATTCTAGAGACCTGAATAAAGGTCC
GTAGAGAAAGGAAGTCAATT

Downstream 100 bases:

>100_bases
CATACTTTACATCAGCTATTGCTAATTAATAATTCTCATTGTTGGCGGGTAAAATTCCGCCAACGTCTTCTTTCTTACGC
CTAAATTACATCATCTCCTG

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH 2; L-serine deaminase 2; L-SD2 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLSIFDIFKVGVGPSSSHTNGPMLAGYHFTQLLSDSMAKVHKVQVDLYGSLSLTGKGHHTDRATVLGLMGNKPDTIKMTS
AKSALQHTIEHGTLSVAGVHEIVFSYDHDIVFHSDNLPLHENGMTITAFDAVGDQVAFETYYSIGGGFIATAAELENGSS
EAEVQVCYPFKSADEMLEKAEQNGLSLGGMILQNERAFREQEEIDQKAEQIWKVMSLCMQRGFDTEGILEGGLNVTRRAP
NLLKKLEANAAVENDPMEIMDWINLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLMYYHRFIKELDNKQLKDFLAVAGA
IGILYKTNASISGAEVGCQGEVGVSSSMAAAGLTALRGGSNEQICIAAEIAMEHSLGMTCDPIGGLVQVPCIERNAMGAM
KAINASRMALKRTSKCLISLDKVIETMYQTGKDMNKKYRETSLGGLAVIHMAPPCE

Sequences:

>Translated_456_residues
MLSIFDIFKVGVGPSSSHTNGPMLAGYHFTQLLSDSMAKVHKVQVDLYGSLSLTGKGHHTDRATVLGLMGNKPDTIKMTS
AKSALQHTIEHGTLSVAGVHEIVFSYDHDIVFHSDNLPLHENGMTITAFDAVGDQVAFETYYSIGGGFIATAAELENGSS
EAEVQVCYPFKSADEMLEKAEQNGLSLGGMILQNERAFREQEEIDQKAEQIWKVMSLCMQRGFDTEGILEGGLNVTRRAP
NLLKKLEANAAVENDPMEIMDWINLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLMYYHRFIKELDNKQLKDFLAVAGA
IGILYKTNASISGAEVGCQGEVGVSSSMAAAGLTALRGGSNEQICIAAEIAMEHSLGMTCDPIGGLVQVPCIERNAMGAM
KAINASRMALKRTSKCLISLDKVIETMYQTGKDMNKKYRETSLGGLAVIHMAPPCE
>Mature_456_residues
MLSIFDIFKVGVGPSSSHTNGPMLAGYHFTQLLSDSMAKVHKVQVDLYGSLSLTGKGHHTDRATVLGLMGNKPDTIKMTS
AKSALQHTIEHGTLSVAGVHEIVFSYDHDIVFHSDNLPLHENGMTITAFDAVGDQVAFETYYSIGGGFIATAAELENGSS
EAEVQVCYPFKSADEMLEKAEQNGLSLGGMILQNERAFREQEEIDQKAEQIWKVMSLCMQRGFDTEGILEGGLNVTRRAP
NLLKKLEANAAVENDPMEIMDWINLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLMYYHRFIKELDNKQLKDFLAVAGA
IGILYKTNASISGAEVGCQGEVGVSSSMAAAGLTALRGGSNEQICIAAEIAMEHSLGMTCDPIGGLVQVPCIERNAMGAM
KAINASRMALKRTSKCLISLDKVIETMYQTGKDMNKKYRETSLGGLAVIHMAPPCE

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=452, Percent_Identity=58.4070796460177, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1788116, Length=452, Percent_Identity=56.858407079646, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI48994925, Length=451, Percent_Identity=55.2106430155211, Blast_Score=500, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48994; Mature: 48994

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIFDIFKVGVGPSSSHTNGPMLAGYHFTQLLSDSMAKVHKVQVDLYGSLSLTGKGHHT
CCCHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCC
DRATVLGLMGNKPDTIKMTSAKSALQHTIEHGTLSVAGVHEIVFSYDHDIVFHSDNLPLH
CCCEEEEECCCCCCEEEECHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCEEEECCCCCEE
ENGMTITAFDAVGDQVAFETYYSIGGGFIATAAELENGSSEAEVQVCYPFKSADEMLEKA
CCCCEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHH
EQNGLSLGGMILQNERAFREQEEIDQKAEQIWKVMSLCMQRGFDTEGILEGGLNVTRRAP
HHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHH
NLLKKLEANAAVENDPMEIMDWINLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLMYYH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RFIKELDNKQLKDFLAVAGAIGILYKTNASISGAEVGCQGEVGVSSSMAAAGLTALRGGS
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
NEQICIAAEIAMEHSLGMTCDPIGGLVQVPCIERNAMGAMKAINASRMALKRTSKCLISL
CCCEEEEEEEHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKVIETMYQTGKDMNKKYRETSLGGLAVIHMAPPCE
HHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCC
>Mature Secondary Structure
MLSIFDIFKVGVGPSSSHTNGPMLAGYHFTQLLSDSMAKVHKVQVDLYGSLSLTGKGHHT
CCCHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCC
DRATVLGLMGNKPDTIKMTSAKSALQHTIEHGTLSVAGVHEIVFSYDHDIVFHSDNLPLH
CCCEEEEECCCCCCEEEECHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCEEEECCCCCEE
ENGMTITAFDAVGDQVAFETYYSIGGGFIATAAELENGSSEAEVQVCYPFKSADEMLEKA
CCCCEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHH
EQNGLSLGGMILQNERAFREQEEIDQKAEQIWKVMSLCMQRGFDTEGILEGGLNVTRRAP
HHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHH
NLLKKLEANAAVENDPMEIMDWINLFAFAVSEENAAGGQVVTSPTNGAAGVIPAVLMYYH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RFIKELDNKQLKDFLAVAGAIGILYKTNASISGAEVGCQGEVGVSSSMAAAGLTALRGGS
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
NEQICIAAEIAMEHSLGMTCDPIGGLVQVPCIERNAMGAMKAINASRMALKRTSKCLISL
CCCEEEEEEEHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DKVIETMYQTGKDMNKKYRETSLGGLAVIHMAPPCE
HHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8385012; 9278503 [H]