Click here to switch to the map view.

The map label for this gene is mntH

Identifier: 156979428

GI number: 156979428

Start: 1160242

End: 1161594

Strand: Reverse

Name: mntH

Synonym: SAHV_1097

Alternate gene names: 156979428

Gene position: 1161594-1160242 (Counterclockwise)

Preceding gene: 156979429

Following gene: 156979414

Centisome position: 40.33

GC content: 32.22

Gene sequence:

>1353_bases
ATGAATAATAAACGACATTCAACAAATGAACAATTAAGTTTAGACGAAATAAACAATACAATTAAATTCGATCATCGCAG
TTCAAATAAACAGAAATTTTTATCATTTCTTGGACCTGGGTTATTAGTCGCTGTTGGTTACATGGATCCCGGAAACTGGA
TAACATCAATGCAAGGTGGCGCCCAATATGGCTATACTTTGCTATTCGTAATTCTTATTTCAAGTTTATCAGCAATGTTA
CTTCAAAGCATGACAGTGAGATTAGGAATAGCAACAGGTATGGACTTAGCTCAAATGACACGACATTATTTATCAAGACC
TATTGCTATAATCTTTTGGATCATTGCAGAACTAGCAATTATCGCTACAGATATTGCTGAGGTTATTGGTAGTGCTATTG
CTCTTAATCTCCTATTTAACATACCTTTAATCGTCGGTGCACTAATAACTGTACTTGATGTATTTTTACTACTATTTATA
ATGAAATATGGTTTTAGAAAAATTGAAGCTATTGTTGGTACATTTATTTTCACAGTGTTATTCATCTTTATATTTGAAGT
CTATATTTCATCACCACAGTTGAATGCTGTGTTAAATGGATTTATACCACATAGTGAAATCATTACAAATAACGGCATTC
TCTATATTGCATTAGGTATTATTGGCGCTACAATTATGCCTCATAATTTGTACTTACATTCATCAATTGTACAATCTAGA
ACATACTCAAGACATAACAATGAAGAAAAGGCGCAAGCGATTAAATTTGCTACGATAGATTCGAACATTCAGTTATCAAT
CGCATTTGTAGTCAATTGCTTATTATTAGTGTTAGGAGCATCACTATTTTTCAACTCGAACGCTGACGATTTAGGTGGTT
TCTATGATTTATATCACGCCTTAAAAACTGAACCTGTACTAGGTGCAACAATGGGTGCAATCATGAGTACATTATTTGCA
GTTGCATTATTAGCGTCAGGTCAAAATTCAACGATTACTGGTACTTTAGCAGGACAAATTGTAATGGAAGGATTTTTAAG
ATTACACATACCAAATTGGTTAAGACGTTTAATTACACGTTCCCTTGCTGTCATTCCTGTTATCGTATGCTTAATCATTT
TTAAAGGTAATGCAGCTAAAATTGAGCAACTACTTGTATTCTCTCAAGTATTTTTAAGTATTGCTCTGCCATTCTGTTTA
ATACCATTACAATTAGCTACTAGTAATAAAGACTTGATGGGACCTTTCTATAATAAAACATGGGTTAATATCATTTCATG
GACACTTATTATTATTCTAAGTATTTTAAATGTCTATTTAATCGTTCAAACATTCCAAGAACTACAAAGTTAA

Upstream 100 bases:

>100_bases
ATAATAATTCATACTTTTAAAAAAATTAAAATAAATTTAGGTTGACCTAAACATTTTATTAGGTTATTATATTGTCCATA
AGAAGTAGAGGTGAGTCAAA

Downstream 100 bases:

>100_bases
AAATAAAACCATTAAAATGTTGGTTGTATCTAATAATTAACAACTTAACATTTTAATGGTTTTTTTGCTATGAACATATT
AATGATAAATATACTCATCG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTFIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS

Sequences:

>Translated_450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTFIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
>Mature_450_residues
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAML
LQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
MKYGFRKIEAIVGTFIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFA
VALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCL
IPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS

Specific function: H(+)-stimulated, highly selective, manganese uptake system

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family

Homologues:

Organism=Homo sapiens, GI109255241, Length=439, Percent_Identity=35.5353075170843, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI295293167, Length=463, Percent_Identity=37.3650107991361, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI295293175, Length=463, Percent_Identity=37.3650107991361, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI295293173, Length=463, Percent_Identity=37.3650107991361, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI10835169, Length=463, Percent_Identity=37.3650107991361, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI295293178, Length=463, Percent_Identity=36.9330453563715, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI295293171, Length=463, Percent_Identity=37.3650107991361, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI295293169, Length=463, Percent_Identity=37.3650107991361, Blast_Score=248, Evalue=7e-66,
Organism=Escherichia coli, GI1788736, Length=423, Percent_Identity=35.2245862884161, Blast_Score=260, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17569473, Length=410, Percent_Identity=38.780487804878, Blast_Score=261, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI193210616, Length=461, Percent_Identity=35.7917570498915, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71999499, Length=469, Percent_Identity=34.1151385927505, Blast_Score=251, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI71993856, Length=249, Percent_Identity=36.144578313253, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324450, Length=425, Percent_Identity=38.1176470588235, Blast_Score=259, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6323062, Length=404, Percent_Identity=42.0792079207921, Blast_Score=259, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6321841, Length=420, Percent_Identity=36.9047619047619, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24648607, Length=471, Percent_Identity=36.3057324840764, Blast_Score=277, Evalue=9e-75,
Organism=Drosophila melanogaster, GI281362176, Length=471, Percent_Identity=36.3057324840764, Blast_Score=277, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24648609, Length=471, Percent_Identity=36.3057324840764, Blast_Score=277, Evalue=9e-75,
Organism=Drosophila melanogaster, GI45553443, Length=440, Percent_Identity=37.2727272727273, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTH_STAA1 (A7X111)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441687.1
- STRING:   A7X111
- EnsemblBacteria:   EBSTAT00000004453
- GeneID:   5560900
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1097
- eggNOG:   COG1914
- GeneTree:   EBGT00050000023664
- HOGENOM:   HBG312498
- OMA:   NWITSVV
- ProtClustDB:   PRK00701
- BioCyc:   SAUR418127:SAHV_1097-MONOMER
- HAMAP:   MF_00221
- InterPro:   IPR023056
- InterPro:   IPR001046
- PANTHER:   PTHR11706
- PRINTS:   PR00447
- TIGRFAMs:   TIGR01197

Pfam domain/function: PF01566 Nramp

EC number: NA

Molecular weight: Translated: 49759; Mature: 49759

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e75a6a0)-; HASH(0x1e5ca094)-; HASH(0x1c1f2c34)-; HASH(0x1c1f0ea4)-; HASH(0x1de674d4)-; HASH(0x1e5de280)-; HASH(0x1e4e2c00)-; HASH(0x1e15dcd8)-; HASH(0x1e592664)-; HASH(0x1e20e684)-; HASH(0x1c5d281c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGG
CCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCHHEEEECCCCCCHHHCCCCC
AQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
IATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTFIFTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
HHHHHHHHHCCCHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHH
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHA
HHHHCCCHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITR
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WVNIISWTLIIILSILNVYLIVQTFQELQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGG
CCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHHHHCCCHHEEEECCCCCCHHHCCCCC
AQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
IATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTFIFTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSR
HHHHHHHHHCCCHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHH
TYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHA
HHHHCCCHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITR
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WVNIISWTLIIILSILNVYLIVQTFQELQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA