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The map label for this gene is 156938220

Identifier: 156938220

GI number: 156938220

Start: 1288262

End: 1289323

Strand: Direct

Name: 156938220

Synonym: Igni_1433

Alternate gene names: NA

Gene position: 1288262-1289323 (Clockwise)

Preceding gene: 156938218

Following gene: 156938225

Centisome position: 99.29

GC content: 56.31

Gene sequence:

>1062_bases
GTGGGCTTACAACGGCGCGGAAGATTGTTAAGAGCTGACGTAGTGTCGACGATATTAGAACGGTTGAGGAAGGCCGGTTA
TCACATAGTCGGCTCGCACAGCGCAGTAAAGAAGTGCCACTGGACTCACGTAGCCTTGACCGAGAGGAGGTTCTGTTATA
AGTGTAAGTTCTACGGCATCGCTTCCCATCGCTGTCTACAAATGACCCCGGCCGTCATATGGTGCTGGCTCCGCTGCTTG
CACTGCTGGAGGGCCGAGCCCGGAGACTTGGGCCTCCAGTGGGACGACACCAAGCTCCCCACAGTGGACGACCCGGCCTT
CATAGCTGAGAAGAGCATCGAGGAGCAGAGGAAGATAATCAGCGGCTACAAGGGCCATCCCAAGGTAGATCCGAAGATGT
TCGAAGAAGCGATGAACCCGAAACACGTAGCCATAAGCTTATCTGGAGAACCTACGCTATACCCGAGGCTCTCAGAACTC
ATCGAAGAGTATTACAAGAGGGGCATGACCACGTTCTTAGTAACCCACGGCGTGAGGCCCGACGCCTTGGCTGAGCTGGA
CCCGGAGCCCACGCAGCTATACCTAAGCTTGGAAGCTTGGGACGAGAAGAGCTTCAAGGAGTTCAACCGTCCGGTACTGC
CGGGTCTGTGGAGCGCGGTGCTTCAGAGCTTAGACATCTTGCCGAGCTTCTCCTCCCCAACAGTAATTAGAATAACCTTG
GTAAAGGGCTTTAATGACCACGAGAGGGCGTTAGAGGGCTTGGCCAAGCTGGTGGAGAGGGGCTACCCGACGTACGTGGA
AGTTAAGGCCTACATGAACGTGGGCTACTCTAGGTACAGGCTCACGAAGGAGAACATGCCCACCCACGCGGAGGTTAGGA
GCTTCGCGGAGAGGTTGGCAGAGAAAATAGGATACGACGTCGTCGACGAACAGAGGTCCAGCAGGGTTGTCCTCTTGTCT
AGAATCGGGAAGCCGATAAGGGTCGGCGAGGGCTGTCCCGGCGGGAAAGCCGGGGAGCTGCCGGAGGGTACAGAGTACGA
GCTCAGCGAGCGCGTGAAATGA

Upstream 100 bases:

>100_bases
CTTGACCGTCAACTTCGGGCCCATTAGGTATCCTTTAGCACAAATTATAAAGAGAACAGTAAGTACCGTTGAGCCTATTA
ACTAAAAAGTCCAGGGACGC

Downstream 100 bases:

>100_bases
TTTATTAGCTTCATAGAGTGCTCACCGAGGGCCCCGTGGCCTAGCCTGGACTAGGGCGCCGGCCTGCGGAGCCGGAGGTC
CCGGGTTCAAATCCCGGCGG

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGLQRRGRLLRADVVSTILERLRKAGYHIVGSHSAVKKCHWTHVALTERRFCYKCKFYGIASHRCLQMTPAVIWCWLRCL
HCWRAEPGDLGLQWDDTKLPTVDDPAFIAEKSIEEQRKIISGYKGHPKVDPKMFEEAMNPKHVAISLSGEPTLYPRLSEL
IEEYYKRGMTTFLVTHGVRPDALAELDPEPTQLYLSLEAWDEKSFKEFNRPVLPGLWSAVLQSLDILPSFSSPTVIRITL
VKGFNDHERALEGLAKLVERGYPTYVEVKAYMNVGYSRYRLTKENMPTHAEVRSFAERLAEKIGYDVVDEQRSSRVVLLS
RIGKPIRVGEGCPGGKAGELPEGTEYELSERVK

Sequences:

>Translated_353_residues
MGLQRRGRLLRADVVSTILERLRKAGYHIVGSHSAVKKCHWTHVALTERRFCYKCKFYGIASHRCLQMTPAVIWCWLRCL
HCWRAEPGDLGLQWDDTKLPTVDDPAFIAEKSIEEQRKIISGYKGHPKVDPKMFEEAMNPKHVAISLSGEPTLYPRLSEL
IEEYYKRGMTTFLVTHGVRPDALAELDPEPTQLYLSLEAWDEKSFKEFNRPVLPGLWSAVLQSLDILPSFSSPTVIRITL
VKGFNDHERALEGLAKLVERGYPTYVEVKAYMNVGYSRYRLTKENMPTHAEVRSFAERLAEKIGYDVVDEQRSSRVVLLS
RIGKPIRVGEGCPGGKAGELPEGTEYELSERVK
>Mature_352_residues
GLQRRGRLLRADVVSTILERLRKAGYHIVGSHSAVKKCHWTHVALTERRFCYKCKFYGIASHRCLQMTPAVIWCWLRCLH
CWRAEPGDLGLQWDDTKLPTVDDPAFIAEKSIEEQRKIISGYKGHPKVDPKMFEEAMNPKHVAISLSGEPTLYPRLSELI
EEYYKRGMTTFLVTHGVRPDALAELDPEPTQLYLSLEAWDEKSFKEFNRPVLPGLWSAVLQSLDILPSFSSPTVIRITLV
KGFNDHERALEGLAKLVERGYPTYVEVKAYMNVGYSRYRLTKENMPTHAEVRSFAERLAEKIGYDVVDEQRSSRVVLLSR
IGKPIRVGEGCPGGKAGELPEGTEYELSERVK

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=312, Percent_Identity=37.5, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI224282123, Length=264, Percent_Identity=35.2272727272727, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI224282125, Length=284, Percent_Identity=34.1549295774648, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6325049, Length=338, Percent_Identity=33.1360946745562, Blast_Score=185, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 40264; Mature: 40133

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLQRRGRLLRADVVSTILERLRKAGYHIVGSHSAVKKCHWTHVALTERRFCYKCKFYGI
CCCCHHCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCEEEEEEEECC
ASHRCLQMTPAVIWCWLRCLHCWRAEPGDLGLQWDDTKLPTVDDPAFIAEKSIEEQRKII
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
SGYKGHPKVDPKMFEEAMNPKHVAISLSGEPTLYPRLSELIEEYYKRGMTTFLVTHGVRP
CCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
DALAELDPEPTQLYLSLEAWDEKSFKEFNRPVLPGLWSAVLQSLDILPSFSSPTVIRITL
CHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
VKGFNDHERALEGLAKLVERGYPTYVEVKAYMNVGYSRYRLTKENMPTHAEVRSFAERLA
ECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHEEEECCCCCCHHHHHHHHHHHH
EKIGYDVVDEQRSSRVVLLSRIGKPIRVGEGCPGGKAGELPEGTEYELSERVK
HHCCCCHHHHCCCCCEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
GLQRRGRLLRADVVSTILERLRKAGYHIVGSHSAVKKCHWTHVALTERRFCYKCKFYGI
CCCHHCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCEEEEEEEECC
ASHRCLQMTPAVIWCWLRCLHCWRAEPGDLGLQWDDTKLPTVDDPAFIAEKSIEEQRKII
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
SGYKGHPKVDPKMFEEAMNPKHVAISLSGEPTLYPRLSELIEEYYKRGMTTFLVTHGVRP
CCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCC
DALAELDPEPTQLYLSLEAWDEKSFKEFNRPVLPGLWSAVLQSLDILPSFSSPTVIRITL
CHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
VKGFNDHERALEGLAKLVERGYPTYVEVKAYMNVGYSRYRLTKENMPTHAEVRSFAERLA
ECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHEEEECCCCCCHHHHHHHHHHHH
EKIGYDVVDEQRSSRVVLLSRIGKPIRVGEGCPGGKAGELPEGTEYELSERVK
HHCCCCHHHHCCCCCEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]