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The map label for this gene is carA [H]

Identifier: 156938187

GI number: 156938187

Start: 1261740

End: 1262861

Strand: Reverse

Name: carA [H]

Synonym: Igni_1400

Alternate gene names: 156938187

Gene position: 1262861-1261740 (Counterclockwise)

Preceding gene: 156938191

Following gene: 156938186

Centisome position: 97.33

GC content: 53.3

Gene sequence:

>1122_bases
TTGAGATGTCGAGGGGATAAGGCGTTCTTAGTGCTAGAGGACCTAAGCATATTCGAGGGCTGCGCGTTCGGTGCCCGGGC
CGTTAGGGTCGGGGAGGTAGTCTTCACCACCACGATGAACGGCTACCCAGAAGCGCTCACGGACCCTTCCTACAAAGGTC
AAATACTGATTATGACTCACCCCATGGTCGGCAACTACGGCGTGCCCGACCCCAACATTATTGATCCAAAGAGCAACTTA
CCTCTCCACTATGAATCTAACGGTATAAAGGTAGAGGGCTTCGTAATAGCTAGGTTGACCAAACCCAACCACTGGGCGTC
GGTTAAGGATTTGGACGAGTGGTTCAAGGAAGAGGGCGTGCCGGGCATTCAAGGCGTGGACACTAGGATGTTGGTCAAAA
AGATAAGGGAAAAAGGAGTGATGATGGGCGCCATTACCACTACCGGAGACGTGGAAGATGCGATAAGGGCACTGGAAAGC
GCGCCGAGGTACGACGAGGTTGATTACGTCTCCTCAGTGCGCCCCCCTAAGGTGATGGAACACGGCTCGGGCGAGCCGGT
CGCGCTCTTGGATTGTGGAGTCAAATACGGAATCGTAAGGGAGCTCGCTTCTCGAGGCCTCAAGGTGATCAGAGTCCCTT
GCGGAGAAGGGCTAAAGATACTGGATGAAGTTAAAGGAGTTGTGCTCGCCAACGGCCCTGGAAACCCCACGATGGCGATG
GAGAAGTATAACTTACACAAGTTCGTAGAGGCCGCATACGAACTCGGACTGCCCATCCTAGCCATATGCTTAGGTCATCA
AATCCTAAACATGACCTTCGGAGGCCGGGTTTACAAAATGAAGTACGGTCATAGGGGGGTTAACAAGCCCGTCAAGGACT
CAGAGGGGAGGTGCTTCATAGTTAGCGAGAACCACGGATACGCGGTGGACCCGAAAACTATAGACAACGTAAAGTTTAGG
AAGTGGTTCGTGAACCCTGATGACAACACCCTCGAGGGGGTGATAAGCAAGGACCCGAAGAGGCCAGTTTTCAGCGTCCA
GTTCCACCCAGAATCCTCCCCGGGTCCTCACGACACCTTGTGGATTTTCGACAAGTTCGCCTCTGAGGTGAAGGCTCAAT
GA

Upstream 100 bases:

>100_bases
CCCGAGTGCATATATCGCTTATGCATGTTTAGACATGTGATTGAAGAAGCTTTAGTTATACTATATAAACCCCCTTTGAA
GCCTTCAGACGCGGGTCCTA

Downstream 100 bases:

>100_bases
ACGACTTGAGGAGCGTTTTGATTATAGGCTCCGGCGCAATCAAGATAGGCGAGGCGGCCGAGTTCGATTATAGCACGAGC
CAAGCGCTGAAGGCCCTCCG

Product: carbamoyl-phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRCRGDKAFLVLEDLSIFEGCAFGARAVRVGEVVFTTTMNGYPEALTDPSYKGQILIMTHPMVGNYGVPDPNIIDPKSNL
PLHYESNGIKVEGFVIARLTKPNHWASVKDLDEWFKEEGVPGIQGVDTRMLVKKIREKGVMMGAITTTGDVEDAIRALES
APRYDEVDYVSSVRPPKVMEHGSGEPVALLDCGVKYGIVRELASRGLKVIRVPCGEGLKILDEVKGVVLANGPGNPTMAM
EKYNLHKFVEAAYELGLPILAICLGHQILNMTFGGRVYKMKYGHRGVNKPVKDSEGRCFIVSENHGYAVDPKTIDNVKFR
KWFVNPDDNTLEGVISKDPKRPVFSVQFHPESSPGPHDTLWIFDKFASEVKAQ

Sequences:

>Translated_373_residues
MRCRGDKAFLVLEDLSIFEGCAFGARAVRVGEVVFTTTMNGYPEALTDPSYKGQILIMTHPMVGNYGVPDPNIIDPKSNL
PLHYESNGIKVEGFVIARLTKPNHWASVKDLDEWFKEEGVPGIQGVDTRMLVKKIREKGVMMGAITTTGDVEDAIRALES
APRYDEVDYVSSVRPPKVMEHGSGEPVALLDCGVKYGIVRELASRGLKVIRVPCGEGLKILDEVKGVVLANGPGNPTMAM
EKYNLHKFVEAAYELGLPILAICLGHQILNMTFGGRVYKMKYGHRGVNKPVKDSEGRCFIVSENHGYAVDPKTIDNVKFR
KWFVNPDDNTLEGVISKDPKRPVFSVQFHPESSPGPHDTLWIFDKFASEVKAQ
>Mature_373_residues
MRCRGDKAFLVLEDLSIFEGCAFGARAVRVGEVVFTTTMNGYPEALTDPSYKGQILIMTHPMVGNYGVPDPNIIDPKSNL
PLHYESNGIKVEGFVIARLTKPNHWASVKDLDEWFKEEGVPGIQGVDTRMLVKKIREKGVMMGAITTTGDVEDAIRALES
APRYDEVDYVSSVRPPKVMEHGSGEPVALLDCGVKYGIVRELASRGLKVIRVPCGEGLKILDEVKGVVLANGPGNPTMAM
EKYNLHKFVEAAYELGLPILAICLGHQILNMTFGGRVYKMKYGHRGVNKPVKDSEGRCFIVSENHGYAVDPKTIDNVKFR
KWFVNPDDNTLEGVISKDPKRPVFSVQFHPESSPGPHDTLWIFDKFASEVKAQ

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=368, Percent_Identity=41.5760869565217, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI21361331, Length=376, Percent_Identity=39.6276595744681, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI169790915, Length=376, Percent_Identity=39.6276595744681, Blast_Score=260, Evalue=1e-69,
Organism=Escherichia coli, GI1786215, Length=386, Percent_Identity=36.2694300518135, Blast_Score=211, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI193204318, Length=370, Percent_Identity=40, Blast_Score=270, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=39.6907216494845, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6322331, Length=402, Percent_Identity=36.81592039801, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI45555749, Length=381, Percent_Identity=38.8451443569554, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24642586, Length=381, Percent_Identity=38.8451443569554, Blast_Score=248, Evalue=5e-66,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41291; Mature: 41291

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCRGDKAFLVLEDLSIFEGCAFGARAVRVGEVVFTTTMNGYPEALTDPSYKGQILIMTH
CCCCCCEEEEEEECCHHHHHCCCCCCEEEECEEEEEEECCCCCCHHCCCCCCCEEEEEEC
PMVGNYGVPDPNIIDPKSNLPLHYESNGIKVEGFVIARLTKPNHWASVKDLDEWFKEEGV
CCCCCCCCCCCCEECCCCCCCEEECCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHCCC
PGIQGVDTRMLVKKIREKGVMMGAITTTGDVEDAIRALESAPRYDEVDYVSSVRPPKVME
CCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH
HGSGEPVALLDCGVKYGIVRELASRGLKVIRVPCGEGLKILDEVKGVVLANGPGNPTMAM
CCCCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHCCCEEEECCCCCCCEEE
EKYNLHKFVEAAYELGLPILAICLGHQILNMTFGGRVYKMKYGHRGVNKPVKDSEGRCFI
EHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCEEEE
VSENHGYAVDPKTIDNVKFRKWFVNPDDNTLEGVISKDPKRPVFSVQFHPESSPGPHDTL
EECCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCEE
WIFDKFASEVKAQ
EEHHHHHHHHCCC
>Mature Secondary Structure
MRCRGDKAFLVLEDLSIFEGCAFGARAVRVGEVVFTTTMNGYPEALTDPSYKGQILIMTH
CCCCCCEEEEEEECCHHHHHCCCCCCEEEECEEEEEEECCCCCCHHCCCCCCCEEEEEEC
PMVGNYGVPDPNIIDPKSNLPLHYESNGIKVEGFVIARLTKPNHWASVKDLDEWFKEEGV
CCCCCCCCCCCCEECCCCCCCEEECCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHCCC
PGIQGVDTRMLVKKIREKGVMMGAITTTGDVEDAIRALESAPRYDEVDYVSSVRPPKVME
CCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH
HGSGEPVALLDCGVKYGIVRELASRGLKVIRVPCGEGLKILDEVKGVVLANGPGNPTMAM
CCCCCCEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHCCCEEEECCCCCCCEEE
EKYNLHKFVEAAYELGLPILAICLGHQILNMTFGGRVYKMKYGHRGVNKPVKDSEGRCFI
EHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCEEEE
VSENHGYAVDPKTIDNVKFRKWFVNPDDNTLEGVISKDPKRPVFSVQFHPESSPGPHDTL
EECCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCEE
WIFDKFASEVKAQ
EEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA