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The map label for this gene is pyrF [H]

Identifier: 156938145

GI number: 156938145

Start: 1212230

End: 1212865

Strand: Direct

Name: pyrF [H]

Synonym: Igni_1358

Alternate gene names: 156938145

Gene position: 1212230-1212865 (Clockwise)

Preceding gene: 156938143

Following gene: 156938146

Centisome position: 93.43

GC content: 54.87

Gene sequence:

>636_bases
TTGGCGCGTTTGCCCGTCGTGATATCCTTGGACCCCCCTAAGGATAAGGGGTGGGACTGGGCGCTGGGCATTGCAGAAGA
AATGAAGGACTTAGTCGTGGCGTTTAAGGTAGGCTGGCCCTTGTTGTTAGAAGGTAAGGAAAAGCTCGGCACGCTCAGAG
AGATGGCCCCAGTCGTCCTCGACCTAAAGCTCGCGGACATAAGTTTCACTATGATAAATATAATAAGGAGGCTCGAGTTC
GACGCAGTTATAGCACACGCCTTTGTAGGGAGGGAGAAAGCTCTTCGGGAGCTAAGGGAAGAGCTAAATAAGCAAGATAA
AGAACTTTACTTAGTAGTGGCGATGAGCCACAAGGGCGCCGACGAGCTGCTGAACAGGATGTGGAGGGAGAACGTCCTAA
TAGCTTACGAACTCGCTGACGGAATCGTAGCCCCGGCGACGAGGCCCGAATTGTTAGTTAAGATCCGTAAGGTGTGGCCC
CGAAAAGTCCTCAGCCCCGGAGTGGGGGTTCAAGGGGCAAGGCCTTGCAGCGCGGTTAAGCTCGGAGCGGACGCCGAGAT
AATAGGTCGCACGGTGACGCGCAACCCCTCACCCCGGGAGTACTTGTTGCGGCTATACTCCGGCTGTAAGGCGTGA

Upstream 100 bases:

>100_bases
GGGGGACGTTCAGACCCAAGGCCTCTAACTTCTTTAAGCTCTTTAGTCTCCTTCCATTCACCCTCAAAAGTCCCCCTCTC
CGAGGCTCGGGGGAAAAGTA

Downstream 100 bases:

>100_bases
AGATTTACTTTCACCCCCCTTATGGAGTTTCCCAAGTTTTTATTCTCGCAAGGAGAGCCGTGACATAGGGAGGAGAGTAC
AATGAGAGGGAAAGCGGTCC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MARLPVVISLDPPKDKGWDWALGIAEEMKDLVVAFKVGWPLLLEGKEKLGTLREMAPVVLDLKLADISFTMINIIRRLEF
DAVIAHAFVGREKALRELREELNKQDKELYLVVAMSHKGADELLNRMWRENVLIAYELADGIVAPATRPELLVKIRKVWP
RKVLSPGVGVQGARPCSAVKLGADAEIIGRTVTRNPSPREYLLRLYSGCKA

Sequences:

>Translated_211_residues
MARLPVVISLDPPKDKGWDWALGIAEEMKDLVVAFKVGWPLLLEGKEKLGTLREMAPVVLDLKLADISFTMINIIRRLEF
DAVIAHAFVGREKALRELREELNKQDKELYLVVAMSHKGADELLNRMWRENVLIAYELADGIVAPATRPELLVKIRKVWP
RKVLSPGVGVQGARPCSAVKLGADAEIIGRTVTRNPSPREYLLRLYSGCKA
>Mature_210_residues
ARLPVVISLDPPKDKGWDWALGIAEEMKDLVVAFKVGWPLLLEGKEKLGTLREMAPVVLDLKLADISFTMINIIRRLEFD
AVIAHAFVGREKALRELREELNKQDKELYLVVAMSHKGADELLNRMWRENVLIAYELADGIVAPATRPELLVKIRKVWPR
KVLSPGVGVQGARPCSAVKLGADAEIIGRTVTRNPSPREYLLRLYSGCKA

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23646; Mature: 23515

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLPVVISLDPPKDKGWDWALGIAEEMKDLVVAFKVGWPLLLEGKEKLGTLREMAPVVL
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHE
DLKLADISFTMINIIRRLEFDAVIAHAFVGREKALRELREELNKQDKELYLVVAMSHKGA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEEECCCCH
DELLNRMWRENVLIAYELADGIVAPATRPELLVKIRKVWPRKVLSPGVGVQGARPCSAVK
HHHHHHHHHCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
LGADAEIIGRTVTRNPSPREYLLRLYSGCKA
ECCCHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARLPVVISLDPPKDKGWDWALGIAEEMKDLVVAFKVGWPLLLEGKEKLGTLREMAPVVL
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHE
DLKLADISFTMINIIRRLEFDAVIAHAFVGREKALRELREELNKQDKELYLVVAMSHKGA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEEEECCCCH
DELLNRMWRENVLIAYELADGIVAPATRPELLVKIRKVWPRKVLSPGVGVQGARPCSAVK
HHHHHHHHHCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
LGADAEIIGRTVTRNPSPREYLLRLYSGCKA
ECCCHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]