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The map label for this gene is cysW [H]

Identifier: 156938127

GI number: 156938127

Start: 1192898

End: 1193638

Strand: Reverse

Name: cysW [H]

Synonym: Igni_1340

Alternate gene names: 156938127

Gene position: 1193638-1192898 (Counterclockwise)

Preceding gene: 156938128

Following gene: 156938126

Centisome position: 91.99

GC content: 51.55

Gene sequence:

>741_bases
ATGAAGGCGGTGGCGATAGCTTTGGCCCTCTTGGGGACTTTGATAATGTTGTCCCCCTTCGCGGTGGTGCCTCCAACTAA
GGTCTTGGAGGAGATGGGGGACAGGGAGGTCTTGTTCGCCGTTTGGCTAAGCTTGGCAACCTCTTTGGTTTCCACCGCTT
TAGTATTGAGCCTAGCGCTCCCTACGGCCTACTCCTTGTCGCGCGGCTTCGCGGGGAGCGGTTTGGTAGAGGCCTTGTTA
AGCGCCCCCAACGCCCTGCCTCCGGTCGCAGTGGGCGCTCTCCTACTGATCTTCTTCTCCCGTACGCCCATAGGTCAGCT
GGTGGACAGCGTAATCCCCATAGTGTTCAGTGTGCCAGGGATAATAATTGCACAAGCCTCTGTCACCTTCCCGCTCGCCT
TAAAGCCGTTGAGGTCCGCCATGAGGGGCTTACACGAAGACGTCTTGCTTATGGCGAGGACGTTAGGTTGCACCAACTTT
TGCTTATTTAAGAAAATTATATTGCCCTCTATTTCAAATACACTAAAATCTTCTTCGGTCTTGGTCTTTACGAGGTCTTT
GGCAGAGTTCGGAGCGACAGTAACCTTGGCCGGCTCAATAAGATTTAAGACGGAAACGCTTCCAATAGCTATATACCTCA
ATATGAGTTCAGGAAACTTAGAAAAGATGATAGCTCTAATAACGTTGGCCTCCTTTCTCGGCTTCGCTTTACTGTCGCTC
TCCAAGAGGTGGGAGAGTTGA

Upstream 100 bases:

>100_bases
AAAAACTTGGGTTTGGCAAAGTTGTTTGTAAAGTTCATCACATCTAAGGAAGCCCTCGAGAAGTGCCGAGAGTACGGCTA
CTCGCCGCCGAGGTGAGAGG

Downstream 100 bases:

>100_bases
TCGTCGCAAGGGACGTTACGATAAGGTACGGAAGGGTCGTGTTGTTCAAAGACTTGAGCTTGCGTGCGGAGGGGGTAACG
CTCCTCGTGGGGCCCAACGG

Product: binding-protein-dependent transporters inner membrane component

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKAVAIALALLGTLIMLSPFAVVPPTKVLEEMGDREVLFAVWLSLATSLVSTALVLSLALPTAYSLSRGFAGSGLVEALL
SAPNALPPVAVGALLLIFFSRTPIGQLVDSVIPIVFSVPGIIIAQASVTFPLALKPLRSAMRGLHEDVLLMARTLGCTNF
CLFKKIILPSISNTLKSSSVLVFTRSLAEFGATVTLAGSIRFKTETLPIAIYLNMSSGNLEKMIALITLASFLGFALLSL
SKRWES

Sequences:

>Translated_246_residues
MKAVAIALALLGTLIMLSPFAVVPPTKVLEEMGDREVLFAVWLSLATSLVSTALVLSLALPTAYSLSRGFAGSGLVEALL
SAPNALPPVAVGALLLIFFSRTPIGQLVDSVIPIVFSVPGIIIAQASVTFPLALKPLRSAMRGLHEDVLLMARTLGCTNF
CLFKKIILPSISNTLKSSSVLVFTRSLAEFGATVTLAGSIRFKTETLPIAIYLNMSSGNLEKMIALITLASFLGFALLSL
SKRWES
>Mature_246_residues
MKAVAIALALLGTLIMLSPFAVVPPTKVLEEMGDREVLFAVWLSLATSLVSTALVLSLALPTAYSLSRGFAGSGLVEALL
SAPNALPPVAVGALLLIFFSRTPIGQLVDSVIPIVFSVPGIIIAQASVTFPLALKPLRSAMRGLHEDVLLMARTLGCTNF
CLFKKIILPSISNTLKSSSVLVFTRSLAEFGATVTLAGSIRFKTETLPIAIYLNMSSGNLEKMIALITLASFLGFALLSL
SKRWES

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=218, Percent_Identity=33.0275229357798, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788764, Length=194, Percent_Identity=30.4123711340206, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786980, Length=177, Percent_Identity=38.4180790960452, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26049; Mature: 26049

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVAIALALLGTLIMLSPFAVVPPTKVLEEMGDREVLFAVWLSLATSLVSTALVLSLAL
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PTAYSLSRGFAGSGLVEALLSAPNALPPVAVGALLLIFFSRTPIGQLVDSVIPIVFSVPG
HHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
IIIAQASVTFPLALKPLRSAMRGLHEDVLLMARTLGCTNFCLFKKIILPSISNTLKSSSV
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
LVFTRSLAEFGATVTLAGSIRFKTETLPIAIYLNMSSGNLEKMIALITLASFLGFALLSL
HHHHHHHHHHCCEEEEEEEEEEEECEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SKRWES
HHHCCC
>Mature Secondary Structure
MKAVAIALALLGTLIMLSPFAVVPPTKVLEEMGDREVLFAVWLSLATSLVSTALVLSLAL
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PTAYSLSRGFAGSGLVEALLSAPNALPPVAVGALLLIFFSRTPIGQLVDSVIPIVFSVPG
HHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
IIIAQASVTFPLALKPLRSAMRGLHEDVLLMARTLGCTNFCLFKKIILPSISNTLKSSSV
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
LVFTRSLAEFGATVTLAGSIRFKTETLPIAIYLNMSSGNLEKMIALITLASFLGFALLSL
HHHHHHHHHHCCEEEEEEEEEEEECEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SKRWES
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]