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The map label for this gene is trpS [H]

Identifier: 156938088

GI number: 156938088

Start: 1156955

End: 1158094

Strand: Reverse

Name: trpS [H]

Synonym: Igni_1301

Alternate gene names: 156938088

Gene position: 1158094-1156955 (Counterclockwise)

Preceding gene: 156938090

Following gene: 156938085

Centisome position: 89.25

GC content: 54.47

Gene sequence:

>1140_bases
TTGAACGGGGACCTCCAGAAGAGCACCGATTATGACCGCTTGATCAAGGTGTTCGGCGTCACTCCCTTGTCAGAAGAGGT
CCTAAACAAACTCCCCGAGAGGCACAAACTGTTCGAAATAGGTTACTTCTTCGCCCACAGGGACTTCGACAAAGTCCTTG
AAGGCTGGGAGAGGGGAGAGGAGTTCGCCATCTTAACGGGGAGGGGGCCCTCCAACGTAATGCACTTGGGCCACATGCTG
CTCTTCGACTTCGTCGCTTGGATGCAGAAGACCTTCAAGGTTCCGGCTTACATACCGTTGAGCGACGACGAGAAGTACGT
GTTCTTGAAGGTAGATAGCTTGAGGGAGGCGGCGTTCTACGCCTATGACAACGCTCTCGACATCGCCGCTTTGGGATTCG
ACGAGAAGAAGACTTACTTCTTTATTTCCACAAAAACCCCAGAAATATACGAGATGTCCGTGGAGCTCAGCACGGAAGTC
ACTTTGAACGAGGTCAAGGCAGTATTCGGCTTCACCGACAGCGACAACCCCGGCAAGTATTTCTACTCCGTCGTCCAGTC
CGCGCACATACTCTTCCCGACCGTCAGAAAGGGGTACCGCTCCTTAGTCCCCATCGCCATCGACCAAGATCCCTACATAA
GGTTGAGCAGGGACATAGCGGAGAGGAAGAAGCTCCCCAAGCCCGCCGCGTTACACAGCAAGTACTTGCCGGGGCTGACC
GGGGAACCGATGAGCGCTAGCAAGCCCGAGACGGCGATATTCTTGGACGACCCACCTAAAGTGATAAAGGAGAAAATTTG
GAAGGCCTTGACGGGCGGCCAGCCCACGGTGAAGGAGCAGAGGGAGAAGGGAGGGGACCCGGAGAGGTGCGTGGTCTTCA
AGTGGTTGGAAGCCTTCGTCTTGGACCCCAAGGAGGCTGAGGAGTGGAAGGGGCGCTGTAGGAGGGGCGAAGTGCTTTGC
GGCGAGTGTAAGAAGAAGCTTTATGAGGGCATAGTGAGGATCCTCAAAGAGCACCACGAGAGGAAGTTGAAGTTAGCGGA
CAAGGCTGACAAGTTCTTCTTACACCCCGTGGACTGGGGAGAGGTGGACAAAGTAAAGGAGAAGACCAAGAGGCTCTTGG
AACAGTTCAATCTTTCTTGA

Upstream 100 bases:

>100_bases
GGACACCTCACCCCCGGAACTGGTACTAGTCGAGCTCTCTGGAGCTACGTCCTCGCTCGCCTAAAATAGTGTTGTGCCCC
TCCTGACCGGGGACAGCCCT

Downstream 100 bases:

>100_bases
GCCACTTCAGCAAGCCCGAGCCCTCGTCCGAGCCCTTCCGCCTCTTCTCGCCCTTCCCCTTCTTCGTGCCCTTCTCGTAC
TCTTTCTTGAGTTCCTTTAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNGDLQKSTDYDRLIKVFGVTPLSEEVLNKLPERHKLFEIGYFFAHRDFDKVLEGWERGEEFAILTGRGPSNVMHLGHML
LFDFVAWMQKTFKVPAYIPLSDDEKYVFLKVDSLREAAFYAYDNALDIAALGFDEKKTYFFISTKTPEIYEMSVELSTEV
TLNEVKAVFGFTDSDNPGKYFYSVVQSAHILFPTVRKGYRSLVPIAIDQDPYIRLSRDIAERKKLPKPAALHSKYLPGLT
GEPMSASKPETAIFLDDPPKVIKEKIWKALTGGQPTVKEQREKGGDPERCVVFKWLEAFVLDPKEAEEWKGRCRRGEVLC
GECKKKLYEGIVRILKEHHERKLKLADKADKFFLHPVDWGEVDKVKEKTKRLLEQFNLS

Sequences:

>Translated_379_residues
MNGDLQKSTDYDRLIKVFGVTPLSEEVLNKLPERHKLFEIGYFFAHRDFDKVLEGWERGEEFAILTGRGPSNVMHLGHML
LFDFVAWMQKTFKVPAYIPLSDDEKYVFLKVDSLREAAFYAYDNALDIAALGFDEKKTYFFISTKTPEIYEMSVELSTEV
TLNEVKAVFGFTDSDNPGKYFYSVVQSAHILFPTVRKGYRSLVPIAIDQDPYIRLSRDIAERKKLPKPAALHSKYLPGLT
GEPMSASKPETAIFLDDPPKVIKEKIWKALTGGQPTVKEQREKGGDPERCVVFKWLEAFVLDPKEAEEWKGRCRRGEVLC
GECKKKLYEGIVRILKEHHERKLKLADKADKFFLHPVDWGEVDKVKEKTKRLLEQFNLS
>Mature_379_residues
MNGDLQKSTDYDRLIKVFGVTPLSEEVLNKLPERHKLFEIGYFFAHRDFDKVLEGWERGEEFAILTGRGPSNVMHLGHML
LFDFVAWMQKTFKVPAYIPLSDDEKYVFLKVDSLREAAFYAYDNALDIAALGFDEKKTYFFISTKTPEIYEMSVELSTEV
TLNEVKAVFGFTDSDNPGKYFYSVVQSAHILFPTVRKGYRSLVPIAIDQDPYIRLSRDIAERKKLPKPAALHSKYLPGLT
GEPMSASKPETAIFLDDPPKVIKEKIWKALTGGQPTVKEQREKGGDPERCVVFKWLEAFVLDPKEAEEWKGRCRRGEVLC
GECKKKLYEGIVRILKEHHERKLKLADKADKFFLHPVDWGEVDKVKEKTKRLLEQFNLS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI47419916, Length=370, Percent_Identity=40.2702702702703, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI47419914, Length=370, Percent_Identity=40.2702702702703, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI47419920, Length=370, Percent_Identity=40.2702702702703, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI47419918, Length=370, Percent_Identity=40.2702702702703, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI239750058, Length=142, Percent_Identity=35.2112676056338, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI310120693, Length=142, Percent_Identity=35.2112676056338, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI239755558, Length=142, Percent_Identity=35.2112676056338, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72001474, Length=365, Percent_Identity=40, Blast_Score=234, Evalue=8e-62,
Organism=Saccharomyces cerevisiae, GI6324475, Length=387, Percent_Identity=40.8268733850129, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI17864462, Length=375, Percent_Identity=39.7333333333333, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24645295, Length=375, Percent_Identity=39.7333333333333, Blast_Score=242, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- InterPro:   IPR020653 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 43686; Mature: 43686

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGDLQKSTDYDRLIKVFGVTPLSEEVLNKLPERHKLFEIGYFFAHRDFDKVLEGWERGE
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCC
EFAILTGRGPSNVMHLGHMLLFDFVAWMQKTFKVPAYIPLSDDEKYVFLKVDSLREAAFY
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHH
AYDNALDIAALGFDEKKTYFFISTKTPEIYEMSVELSTEVTLNEVKAVFGFTDSDNPGKY
HCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCHHH
FYSVVQSAHILFPTVRKGYRSLVPIAIDQDPYIRLSRDIAERKKLPKPAALHSKYLPGLT
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHCCCCCHHHHHHCCCCCC
GEPMSASKPETAIFLDDPPKVIKEKIWKALTGGQPTVKEQREKGGDPERCVVFKWLEAFV
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
LDPKEAEEWKGRCRRGEVLCGECKKKLYEGIVRILKEHHERKLKLADKADKFFLHPVDWG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
EVDKVKEKTKRLLEQFNLS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGDLQKSTDYDRLIKVFGVTPLSEEVLNKLPERHKLFEIGYFFAHRDFDKVLEGWERGE
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCC
EFAILTGRGPSNVMHLGHMLLFDFVAWMQKTFKVPAYIPLSDDEKYVFLKVDSLREAAFY
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHH
AYDNALDIAALGFDEKKTYFFISTKTPEIYEMSVELSTEVTLNEVKAVFGFTDSDNPGKY
HCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCHHH
FYSVVQSAHILFPTVRKGYRSLVPIAIDQDPYIRLSRDIAERKKLPKPAALHSKYLPGLT
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEHHHHHHHHHCCCCCHHHHHHCCCCCC
GEPMSASKPETAIFLDDPPKVIKEKIWKALTGGQPTVKEQREKGGDPERCVVFKWLEAFV
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
LDPKEAEEWKGRCRRGEVLCGECKKKLYEGIVRILKEHHERKLKLADKADKFFLHPVDWG
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
EVDKVKEKTKRLLEQFNLS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA