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The map label for this gene is lhr [C]

Identifier: 156938074

GI number: 156938074

Start: 1142065

End: 1144161

Strand: Reverse

Name: lhr [C]

Synonym: Igni_1287

Alternate gene names: 156938074

Gene position: 1144161-1142065 (Counterclockwise)

Preceding gene: 156938078

Following gene: 156938068

Centisome position: 88.18

GC content: 60.66

Gene sequence:

>2097_bases
TTGAGGGCCCAGAACCCCGAGGGAGCGAGGTTAGGGTTAAAGGAGTGGTTGGAGGAGAGGGGCATAAGGCGGCTGTTCCC
CGTCCAAGAGCTCGCCCTCCAGAAGGGACTGACTGAGTTCAAGAACTTGTTGGTCTCCGCTCCCACGGGCTCGGGCAAGA
CGCTCGTAGCCGAGATGGCTATAAAGAACGCCCTCGACAACGGCTACAAGGCCGTCTACCTAACCCCACTGCGGAGCTTG
GCCTTCGAAAAGTACGCCTCCTTGAAGAAAATATTCAAGGACTCGAAAGTGGCGCTGAGCGTCGGCGACTACCACGCCCC
CGAGGTGGGGGAGGCGGACGTCTTAGTGGCTACGTACGAGAGGATGGACTCCTTGCTGAGGCACAACTCTCCTTGGTTGA
AGGAAGTGGGGACTGTAGTGGTGGACGAGGTCCACTACGTGGGCGACGAGGAGAGGGGCCCGACGTTGGAGGTTGTAGTG
ACTAGGTTAAAGCTAATGGGAAAGCAGATAGTCGCGCTCTCGGCCACCGTGGGGAACCCGGAGGACTTGGCCTCTTGGTT
GGACGCGGAACTCGTCACCCACGACTGGAGGCCCGTGAAGCTGGAGGAAGGCGTAATGGACCCGTCCAGCTACGAGGTGT
TGTTCGAGGACAGAGTCGAGGAAGTGAAGGAGGTCTTGAGCGACCCGGGCTTGGACGCGGCCCTCCACTACATGAGGGAG
GGCCAAGCGCTCTACTTCGCTAGCACGAGGAAGAGGGCCGAGAACGCGGCAAAGAAGATATCGAAGTTGTTGAAACCCGA
TAAGGTTACCAAGGAGTGGGCAGAGAGGGTCAGGATTGAGGTAGAAGGGGAGCTCGGCGAGGTCTTGGCGAAGATGGTGG
AGAGGGGAGCCGCCTTCCACCACGCCGGGCTCACCAACGAGGCCCGACTGCTCGTGGAGGAGGCCTTCCGCTCCGGGGCG
ATCAAGTTCGTCGCCGCCACCCCCACGCTGGCCGCTGGGGTCAACTTGCCGGCCAGAGCGGTCGTGATCGAGAGGTACAC
GAGGTACACGGACGAGGGGGAGGCGCCGATCTCGGTCTCAGAGTACAAGCAGATGGCCGGGAGGGCGGGCAGGCCGGGCT
TGGACGTTAAGGGCACCTCAGTGTTAGTAGCTAGGCCGAAGGCCCCTCCGGAGGAGGTCTACGAGAGGTACGTCTTGGGC
CAGCCGGAGGACGTGCGGAGCGCCTTGACCAGCGCCCGAGCGTTGAGAAGATCTCTCTTAGGGCTGATAGCCTCCAAGGC
AGTTAACAGCGAGGCGGAGTTGGTGGAGTTCATAGAGGAGACCCTCTTCGGGGTTACAGAAGGGGCAGCAAACGCGATAG
ACGACGCGAGGAGGTCGCTGGAGTTCCTAAAGGGGGCTGGTTTGGTGGAAGGAGTCAAGGCTACGCCGTTGGGAACGGTA
GTCGCCAAACAGTACGTGGACCCACTAGGGGCAAAGGTAGTTCTGGGGGCCCTGAAGCGCCGCAAGGGCAAGACTACCGC
TTTGGGGTACTTGCACTTGGTCGCCGTCACCCCGGACATGCCCAAGAGGGGGCTGAGGAGCTCGGAGGTGAGGGAGCTCT
GGAGGGTGGCGGAGGAGAGGTTCGACGAGCTCTTGATAAGGGATGACGAGTACGTGAGCGAGTCGACGGCGTTGAGCGCG
TTGAAGGTCGCTCTAGCCCTGGAGAGCTGGGTGAAGGAGGAGCCGGAGGAGGTGATAGCGAAGAAGTACGGCTTCTACCC
GGGAGACCTCAGAGTGTTGAGCGACACGGCCGCGTGGCTGGTCCATGCATATTCTGAAATAGCTAAGTTCGTCGGTCTGT
ACAAACACTCCGAGGCGCTGGCGGAGCTGGAGCTCCGCTTGAAGTACGGCGTCTCCGAAGAGCTCGTCGAGTTAGTGCAG
ATACCCTACATAGGTAGGGTAAGGGCCAGGGCGCTTTGGAACGCCGGAATAAGGTCTAAAGAGGACTTCGTCAAGAGGGC
TGACCTAGCTGCGAGGGTGGTCGGTAAGGGGGTCGTTAAGCGGGCCTTAGAGGCGATGGGCTTGGGCTACGGGCTGGTCA
AGTGGGTTAAGCCTTGA

Upstream 100 bases:

>100_bases
GAGCCCTCCGGCGTCGACGGCTCTACCCTCACCCTCAAGTTCCTCTTGCCCTCACAAGGGCCGTCCGTAAGTGCCGGAGT
ATTCAGCATTACTTTAACGC

Downstream 100 bases:

>100_bases
CCGGCTCTGAGGTTATCCACGAGAACTTCTCCGAGCCCTCAACCGGGAGCTTCAGCAGCTCCACGTAACCGAAGGCGCTA
AGCGCGACAGCCTCCATTAA

Product: DEAD/DEAH box helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRAQNPEGARLGLKEWLEERGIRRLFPVQELALQKGLTEFKNLLVSAPTGSGKTLVAEMAIKNALDNGYKAVYLTPLRSL
AFEKYASLKKIFKDSKVALSVGDYHAPEVGEADVLVATYERMDSLLRHNSPWLKEVGTVVVDEVHYVGDEERGPTLEVVV
TRLKLMGKQIVALSATVGNPEDLASWLDAELVTHDWRPVKLEEGVMDPSSYEVLFEDRVEEVKEVLSDPGLDAALHYMRE
GQALYFASTRKRAENAAKKISKLLKPDKVTKEWAERVRIEVEGELGEVLAKMVERGAAFHHAGLTNEARLLVEEAFRSGA
IKFVAATPTLAAGVNLPARAVVIERYTRYTDEGEAPISVSEYKQMAGRAGRPGLDVKGTSVLVARPKAPPEEVYERYVLG
QPEDVRSALTSARALRRSLLGLIASKAVNSEAELVEFIEETLFGVTEGAANAIDDARRSLEFLKGAGLVEGVKATPLGTV
VAKQYVDPLGAKVVLGALKRRKGKTTALGYLHLVAVTPDMPKRGLRSSEVRELWRVAEERFDELLIRDDEYVSESTALSA
LKVALALESWVKEEPEEVIAKKYGFYPGDLRVLSDTAAWLVHAYSEIAKFVGLYKHSEALAELELRLKYGVSEELVELVQ
IPYIGRVRARALWNAGIRSKEDFVKRADLAARVVGKGVVKRALEAMGLGYGLVKWVKP

Sequences:

>Translated_698_residues
MRAQNPEGARLGLKEWLEERGIRRLFPVQELALQKGLTEFKNLLVSAPTGSGKTLVAEMAIKNALDNGYKAVYLTPLRSL
AFEKYASLKKIFKDSKVALSVGDYHAPEVGEADVLVATYERMDSLLRHNSPWLKEVGTVVVDEVHYVGDEERGPTLEVVV
TRLKLMGKQIVALSATVGNPEDLASWLDAELVTHDWRPVKLEEGVMDPSSYEVLFEDRVEEVKEVLSDPGLDAALHYMRE
GQALYFASTRKRAENAAKKISKLLKPDKVTKEWAERVRIEVEGELGEVLAKMVERGAAFHHAGLTNEARLLVEEAFRSGA
IKFVAATPTLAAGVNLPARAVVIERYTRYTDEGEAPISVSEYKQMAGRAGRPGLDVKGTSVLVARPKAPPEEVYERYVLG
QPEDVRSALTSARALRRSLLGLIASKAVNSEAELVEFIEETLFGVTEGAANAIDDARRSLEFLKGAGLVEGVKATPLGTV
VAKQYVDPLGAKVVLGALKRRKGKTTALGYLHLVAVTPDMPKRGLRSSEVRELWRVAEERFDELLIRDDEYVSESTALSA
LKVALALESWVKEEPEEVIAKKYGFYPGDLRVLSDTAAWLVHAYSEIAKFVGLYKHSEALAELELRLKYGVSEELVELVQ
IPYIGRVRARALWNAGIRSKEDFVKRADLAARVVGKGVVKRALEAMGLGYGLVKWVKP
>Mature_698_residues
MRAQNPEGARLGLKEWLEERGIRRLFPVQELALQKGLTEFKNLLVSAPTGSGKTLVAEMAIKNALDNGYKAVYLTPLRSL
AFEKYASLKKIFKDSKVALSVGDYHAPEVGEADVLVATYERMDSLLRHNSPWLKEVGTVVVDEVHYVGDEERGPTLEVVV
TRLKLMGKQIVALSATVGNPEDLASWLDAELVTHDWRPVKLEEGVMDPSSYEVLFEDRVEEVKEVLSDPGLDAALHYMRE
GQALYFASTRKRAENAAKKISKLLKPDKVTKEWAERVRIEVEGELGEVLAKMVERGAAFHHAGLTNEARLLVEEAFRSGA
IKFVAATPTLAAGVNLPARAVVIERYTRYTDEGEAPISVSEYKQMAGRAGRPGLDVKGTSVLVARPKAPPEEVYERYVLG
QPEDVRSALTSARALRRSLLGLIASKAVNSEAELVEFIEETLFGVTEGAANAIDDARRSLEFLKGAGLVEGVKATPLGTV
VAKQYVDPLGAKVVLGALKRRKGKTTALGYLHLVAVTPDMPKRGLRSSEVRELWRVAEERFDELLIRDDEYVSESTALSA
LKVALALESWVKEEPEEVIAKKYGFYPGDLRVLSDTAAWLVHAYSEIAKFVGLYKHSEALAELELRLKYGVSEELVELVQ
IPYIGRVRARALWNAGIRSKEDFVKRADLAARVVGKGVVKRALEAMGLGYGLVKWVKP

Specific function: Unknown

COG id: COG1204

COG function: function code R; Superfamily II helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI139394648, Length=764, Percent_Identity=28.6649214659686, Blast_Score=216, Evalue=7e-56,
Organism=Homo sapiens, GI110556640, Length=751, Percent_Identity=27.2969374167776, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI130484567, Length=416, Percent_Identity=32.2115384615385, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI76880486, Length=435, Percent_Identity=30.8045977011494, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI67782311, Length=431, Percent_Identity=29.0023201856148, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169218225, Length=641, Percent_Identity=24.1809672386895, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI40217847, Length=401, Percent_Identity=28.6783042394015, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI193211480, Length=438, Percent_Identity=28.310502283105, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI222831595, Length=111, Percent_Identity=39.6396396396396, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI149274648, Length=101, Percent_Identity=34.6534653465347, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787942, Length=398, Percent_Identity=25.8793969849246, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71995032, Length=706, Percent_Identity=27.7620396600567, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17537519, Length=431, Percent_Identity=29.6983758700696, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI86563272, Length=407, Percent_Identity=29.4840294840295, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17542826, Length=413, Percent_Identity=30.7506053268765, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17537127, Length=528, Percent_Identity=27.6515151515151, Blast_Score=139, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI133930973, Length=187, Percent_Identity=37.4331550802139, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995036, Length=418, Percent_Identity=28.2296650717703, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552356, Length=107, Percent_Identity=37.3831775700935, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI9755332, Length=382, Percent_Identity=31.9371727748691, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321710, Length=556, Percent_Identity=26.0791366906475, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321020, Length=417, Percent_Identity=29.2565947242206, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322411, Length=446, Percent_Identity=28.9237668161435, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323430, Length=189, Percent_Identity=33.8624338624339, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17933644, Length=742, Percent_Identity=28.7061994609164, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24660651, Length=478, Percent_Identity=31.7991631799163, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24647182, Length=432, Percent_Identity=30.5555555555556, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574898, Length=402, Percent_Identity=30.5970149253731, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17864608, Length=458, Percent_Identity=29.9126637554585, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17933658, Length=122, Percent_Identity=37.7049180327869, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR010995
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR022965 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 77067; Mature: 77067

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAQNPEGARLGLKEWLEERGIRRLFPVQELALQKGLTEFKNLLVSAPTGSGKTLVAEMA
CCCCCCCCCCCCHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
IKNALDNGYKAVYLTPLRSLAFEKYASLKKIFKDSKVALSVGDYHAPEVGEADVLVATYE
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHH
RMDSLLRHNSPWLKEVGTVVVDEVHYVGDEERGPTLEVVVTRLKLMGKQIVALSATVGNP
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCH
EDLASWLDAELVTHDWRPVKLEEGVMDPSSYEVLFEDRVEEVKEVLSDPGLDAALHYMRE
HHHHHHHHHHHHHCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GQALYFASTRKRAENAAKKISKLLKPDKVTKEWAERVRIEVEGELGEVLAKMVERGAAFH
CCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEECCCHHHHHHHHHHCCCHHH
HAGLTNEARLLVEEAFRSGAIKFVAATPTLAAGVNLPARAVVIERYTRYTDEGEAPISVS
HCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHH
EYKQMAGRAGRPGLDVKGTSVLVARPKAPPEEVYERYVLGQPEDVRSALTSARALRRSLL
HHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GLIASKAVNSEAELVEFIEETLFGVTEGAANAIDDARRSLEFLKGAGLVEGVKATPLGTV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VAKQYVDPLGAKVVLGALKRRKGKTTALGYLHLVAVTPDMPKRGLRSSEVRELWRVAEER
HHHHHHCCCHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
FDELLIRDDEYVSESTALSALKVALALESWVKEEPEEVIAKKYGFYPGDLRVLSDTAAWL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VHAYSEIAKFVGLYKHSEALAELELRLKYGVSEELVELVQIPYIGRVRARALWNAGIRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
EDFVKRADLAARVVGKGVVKRALEAMGLGYGLVKWVKP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MRAQNPEGARLGLKEWLEERGIRRLFPVQELALQKGLTEFKNLLVSAPTGSGKTLVAEMA
CCCCCCCCCCCCHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
IKNALDNGYKAVYLTPLRSLAFEKYASLKKIFKDSKVALSVGDYHAPEVGEADVLVATYE
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHH
RMDSLLRHNSPWLKEVGTVVVDEVHYVGDEERGPTLEVVVTRLKLMGKQIVALSATVGNP
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCH
EDLASWLDAELVTHDWRPVKLEEGVMDPSSYEVLFEDRVEEVKEVLSDPGLDAALHYMRE
HHHHHHHHHHHHHCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GQALYFASTRKRAENAAKKISKLLKPDKVTKEWAERVRIEVEGELGEVLAKMVERGAAFH
CCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEECCCHHHHHHHHHHCCCHHH
HAGLTNEARLLVEEAFRSGAIKFVAATPTLAAGVNLPARAVVIERYTRYTDEGEAPISVS
HCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHH
EYKQMAGRAGRPGLDVKGTSVLVARPKAPPEEVYERYVLGQPEDVRSALTSARALRRSLL
HHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GLIASKAVNSEAELVEFIEETLFGVTEGAANAIDDARRSLEFLKGAGLVEGVKATPLGTV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VAKQYVDPLGAKVVLGALKRRKGKTTALGYLHLVAVTPDMPKRGLRSSEVRELWRVAEER
HHHHHHCCCHHHHHHHHHHHCCCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
FDELLIRDDEYVSESTALSALKVALALESWVKEEPEEVIAKKYGFYPGDLRVLSDTAAWL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VHAYSEIAKFVGLYKHSEALAELELRLKYGVSEELVELVQIPYIGRVRARALWNAGIRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
EDFVKRADLAARVVGKGVVKRALEAMGLGYGLVKWVKP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA